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Table 2 Predictors of UTIa antibiotic prescriptions among those ≥ 75 yearsb

From: Antibiotic use in the care home setting: a retrospective cohort study analysing routine data

  All ≥ 75 years ≥75 years without a catheter ≥ 75 years with a catheter
  Unadjusted odds ratio Adjusted odds ratioc Adjusted odds ratioc Adjusted odds ratioc
Care home resident 2.66 (2.51–2.82; p < 0.001) 2.12 (1.99–2.26; p < 0.001) 2.19 (2.05–2.34; p < 0.001) 1.40 (1.08–1.82; p = 0.012)
Female 2.57 (2.45–2.69; p < 0.001) 2.85 (2.72–2.99; p < 0.001) 2.95 (2.80–3.09; p < 0.001) 1.46 (1.16–1.84; p = 0.001)
Age 1.03 (1.03–1.04; p < 0.001) 1.01 (1.00–1.01; p = 0.003) 1.01 (1.00–1.01; p = 0.004) 0.99 (0.98–1.01; p = 0.574)
Urinary catheter 8.08 (7.31–8.93; p < 0.001) 11.3 (10.1–12.6; p < 0.001) N/A N/A
Comorbidity     
 • None 1.00 1.00 1.00 1.00
 • One 1.65 (1.53–1.79; p < 0.001) 1.67 (1.54–1.81; p < 0.001) 1.71 (1.58–1.86; p < 0.001) 0.86 (0.56–1.31; p = 0.475)
 • Two 2.12 (1.97–2.28; p < 0.001) 2.04 (1.89–2.20; p < 0.001) 2.10 (1.94–2.27; p < 0.001) 0.96 (0.65–1.42; p = 0.832)
 • Three or more 2.82 (2.64–3.02; p < 0.001) 2.61 (2.44–2.80; p < 0.001) 2.71 (2.53–2.91; p < 0.001) 1.00 (0.71–1.42; p = 0.989)
  1. aTrimethoprim and nitrofurantoin, the dominant antibiotics used for urinary tract infection in the UK and rarely used for alternative conditions
  2. bAll ≥75 years not prescribed long term prophylaxis against recurrent UTI, both in care homes and not in care homes (N = 101,373)
  3. cCare home resident status adjusted for gender, age, presence of urinary catheter and number of comorbidity according to Quality and Outcomes Framework, OR (95 % CI; p-value)