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Table 3 Multivariate analysis exploring the mediators of contrast sensitivity and moderate-to-vigorous physical activity in age-related macular degeneration

From: Physical activity restriction in age-related eye disease: a cross-sectional study exploring fear of falling as a potential mediator

Variable Interval Model 0: Model 1: Model 2: Model 3:
Univariate Modelsa Multivariate Models Model 1+ FoF Model 1+ Driving
Log CS, binocular 0.1 Log units worse 0.86 (0.80, 0.91) 0.89 (0.83, 0.95) 1.02 (0.95, 1.10) 0.93 (0.86, 0.99)
FoFb Person measure score 1.56 (1.41, 1.73) -- 1.70 (1.51, 1.93) --
Limited driving vs Driving without limitation 0.71 (0.45, 1.10) -- -- 0.92 (0.56, 1.52)
Not driving vs Driving without limitation 0.37 (0.22, 0.61) -- -- 0.40 (0.22, 0.74)
Age 5 y older 1.07 (0.90, 1.28) 1.58 (1.28, 1.96) 1.18 (0.95, 1.46) 1.69 (1.38, 2.08)
Female vs Male 0.40 (0.27, 0.59) 0.33 (0.22, 0.50) 1.25 (0.81, 1.93) 0.33 (0.22, 0.49)
AA vs Non-AA 0.12 (0.02, 0.58) 0.41 (0.07, 2.46) 0.30 (0.05, 1.84) 0.45 (0.08, 2.49)
Education 4 y less 2.4 (1.6, 3.6) 2.18 (1.45, 3.26) 3.94 (2.57, 6.02) 2.44 (1.61, 3.69)
Comorbidity 1 more Illness 0.85 (0.87, 0.96) 0.73 (0.64, 0.83) 0.81 (0.71, 0.93) 0.79 (0.70, 0.90)
  1. MVPA = moderate-to-vigorous physical activity; CS = contrast sensitivity; y = years; FoF = fear of falling; vs = versus; AA = African-American
  2. Values in bold indicate p < 0.05
  3. aMVPA is the dependent variable in each model. Model 0 contains bivariate models of each covariate with MVPA. Model 1 contains CS, Age, Sex, Race, Education, and Comorbidity as independent variables. Model 2 adds FoF as a possible mediator between CS and MVPA
  4. bPerson measure scores are derived from Rasch analytic model. Higher scores indicate greater ability, or less fear of falling