Relationship between biomarkers of inflammation, oxidative stress and endothelial/microcirculatory function in successful aging versus healthy youth: a transversal study

Table 2 Inflammatory and oxidative stress biomarkers

	Young Controls (n = 24)	Healthy Elderly (n = 11)
sVCAM (ng/ml)	19.3 [16.7-21.9]	29,7 [25-35]*	0.017
sICAM-1 (ng/ml)	9.8 [9.3-11.2]	11.5 [9.7-13.6]	0.057
sE-SELECTIN (ng/ml)	2.2 [1.1-3.1]	2.6 [2.4-3.4]*	0.042
Oxidized – LDL (mU/l)	35449 [31138-41238]	43909 [42154-47075]*	0.015
IL-1 beta (pg/ml)	0.4 [0.2-0.7]	0.3 [0.1-0.6]	0.515
IL-6 HS (pg/ml)	2.2 [1.5-5.4]	2.2 [1.1-2.9]	0.879
TNF-alpha (pg/ml)	1.8 [1.5-3.3]	1.8 [1.38-2.40]	1.000
hS C-reactive protein, mg/dl (mg/dl)	0.30 [0.07-0.59]	0.44 [0.23-0.63]	0.584

sVCAM= soluble Vascular Cell Adhesion Molecule; sICAM= soluble Intercellular Adhesion Molecule; sE-SELECTIN = soluble endothelial selectin; IL-1 beta = Interleukin-1 beta; IL-6 HS = Interleukin-6 High Sensitivity; TNF-alpha = Tumor Necrosis Factor–alpha. *p < 0.05 related to Young Controls.

ISSN: 1471-2318