- Meeting abstract
- Open Access
Radical surgical treatment of duodeno-pancreatic neoplasms in elderly patients: our experience
BMC Geriatrics volume 9, Article number: A63 (2009)
Aim of the study
To evaluate the results of surgical treatment of duodeno-pancreatic neoplasms in elderly patients, in terms of mortality, morbidity and survival.
Materials and methods
From 01/01/1994 to 01/10/2008 48 patients aged more than 65 years old, 29 males (60.42%), 19 females (39.58%) mean age 67 years old (range 65–81), underwent radical surgery for duodeno-pancreatic neoplasms.
24 patients (50.00%) were affected by pancreatic head carcinoma, 5 (10.42%) by distal common bile duct cancer, 11 (22.92%) by ampullary cancer, 4 (8.32%) by duodenal carcinoma, 1 (2.08%) by infiltrating right colon carcinoma, 2 (4.16%) by distal pancreatic cancer, 1 by focal pancreatitis.
44 patients (91.67%) underwent pancreaticoduodenectomy (37 standard, 7 extended, with Wirsung gastric anastomosis in 19 cases, Wirsung-jejunal anastomosis in 34, and Wirsung closure in 1); 3 patients (6.25%) underwent total pancreaticoduodenectomy, 1 patient distal pancreatectomy. 2 patients were also treated with IORT. Perioperative mortality was 4.16%, morbidity was 10.42% (2 cases of peritoneal bleeding, 3 gastrointestinal bleeding, 2 portal thrombosis, 1 pancreatic fistula). 3 years survivorship was 22% (N0:18%, N1:2%); 5 years survivorship was 16% (N0:14%, N1:2%). Causes of death were liver metastasis (29.17%), local recurrence (10.42%), cardiovascular and cerebrovascular events (4.16%).
Radical surgery for duodeno-pancreatic tumors could be a good option in elderly patients; despite comorbidities, in our experience we observed good results in terms of survival and morbidity, similar to what observed in younger patients.