In dependent variables | Unadjusted regression coefficients | Adjusted regression coefficients | ||
---|---|---|---|---|
Coeff. (95% CI) | p-value | Coeff. (95% CI) | p-value | |
Effect of main variables 1 | ||||
Time | 0.19 (0.15; 0.24) | <0.001 | 0.20 (0.16; 0.25) | <0.001 |
Time* time | -0.001 (-0.001; -0.0005) | <0.001 | -0.001 (-0.002; -0.001) | <0.001 |
CDR sum of boxes | 0.72 (0.65; 0.79) | <0.001 | 0.61 (0.53; 0.69) | <0.001 |
Time* CDR sum of boxes | -0.004 (-0.007; -0.001) | 0.007 | -0.004 (-0.007; -0.001) | 0.013 |
Effect of additional variables at baseline 2 | ||||
Length of stay | 0.002 (0.001; 0.002) | <0.001 | 0.001 (0.001; 0.001) | <0.001 |
Socio –demographic information | ||||
Age (years) | -0.02 (-0.06; 0.02) | 0.312 | -0.05 (-0.09; -0.01) | 0.007 |
Women | -0.33 (-1.03; 0.38) | 0.362 | -0.62 (-1.25; 0.01) | 0.054 |
Single | -0.80 (-1.58; -0.03) | 0.042 | -0.72 (-1.41; -0.03) | 0.041 |
Ten years of education or less | 0.46 (-0.25; 1.17) | 0.206 | 0.48 (-0.12; 1.07) | 0.117 |
Somatic health difficulties | ||||
Co-morbidity index | 0.21 (-0.04; 0.46) | 0.100 | 0.32 (0.11; 0.53) | 0.003 |
No severe vision impairment | 1.65 (0.77; 2.53) | <0.001 | 0.93 (0.19; 1.67) | 0.014 |
No severe hearing impairment | -0.79 (-1.70; 0.13) | 0.091 | -0.12 (-0.90; 0.66) | 0.765 |
Degree of neuropsychiatric problems | ||||
Agitation sub-syndrome | 0.08 (0.04; 0.12) | <0.001 | 0.01 (-0.0; 0.04) | 0.546 |
Psychosis sub- syndrome | 0.04 (-0.02; 0.10) | 0.150 | ||
Affective sub-syndrome | 0.02 (-0.04; 0.07) | 0.602 | ||
Apathy | 0.35 (0.27; 0.43) | <0.001 | 0.10 (0.03; 0.18) | 0.007 |
Use of psychotropic medication | ||||
Antipsychotics | 0.72 (0.01; 1.42) | 0.046 | -0.08 (-0.69; 0.53) | 0.802 |
Antidepressants | -0.56 (-1.19; 0.07) | 0.081 | -0.33 (-0.86; 0.20) | 0.225 |
Anxiolytics | -0.28 (-1.01; 0.44) | 0.443 | -0.70 (-1.31; -0.10) | 0.024 |
Sedatives | -0.65 (-1.36; 0.05) | 0.070 | -0.12 (-0.70; 0.47) | 0.701 |
Cognitive enhancers | -3.23 (-4.09; -2.36) | <0.001 | -1.81 (-2.58; -1.05) | <0.001 |