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Table 4 Accuracy of phalangeal RA in predicting osteoporosis

From: Calcaneal quantitative ultrasound and Phalangeal radiographic absorptiometry alone or in combination in a triage approach for assessment of osteoporosis: a study of older women with a high prevalence of falls

Phalangeal RA (n = 245)

Youden1

UK-NOS triage approach 90% certainty level

UK-NOS triage approach 95% certainty level

RA T-score Upper/lower cutoff

-2.22

-0.65/–2.95

0.28/–3.32

Sensitivity (95% CI)

67.6 (57.9–76.3)

90.7 (83.6–95.5)

95.4 (89.5–98.5)

Specificity (95% CI)

78.1 (70.2–84.7)

90.5 (84.3–94.9)

95.6 (90.7–98.4)

PPV (95% CI)

70.9 (61.1–79.4)

75.0 (61.1–86)

82.9 (66.4–93.4)

NPV (95% CI)

75.4 (67.4–82.2)

81.1 (68–90.6)

77.3 (54.6–92.2)

False negative n (%)

35 (14.3)

10 (4.1)

5 (2.0)

False positive n (%)

30 (12.2)

13 (5.3)

6 (2.5)

DXA scans avoided n (%)

NA

105 (42.9)

57 (23.3)

  1. Accuracy of phalangeal RA in predicting osteoporosis applying the optimal cutoff and UK-NOS triage approach at 90% and 95% certainty levels. 1the optimal cutoff calculated according the Youden index [30]. Abbreviations: RA Radiographic Absorptiometry, UK-NOS United Kingdom National Osteoporosis Society, PPV Positive Predictive Value, NPV Negative Predictive Value, DXA Dual Energy X-ray Absorptiometry, CI Confidence Interval, NA not available.