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Table 4 Logistic regression model: factors predicting gastrointestinal bleeding within 120 days of incident bisphosphonate use

From: The association between serious upper gastrointestinal bleeding and incident bisphosphonate use: a population-based nested cohort study

Variable Adjusted odds ratio (95% CI) p -Value
Constant 0.002 0.000
Age (y)
 ≤ 80 1 (reference)  
 > 80 2.03 (1.40, 2.94) 0.000
Sex
 Female 1 (reference)  
 Male 1.69 (1.05, 2.72) 0.030
Past history of gastric ulcer disease
 No 1 (reference)  
 Yes 1.90 (1.21, 3.01) 0.006
Past history of serious GI bleeding
 No 1 (reference)  
 Yes 2.28 (1.29, 4.03) 0.005
NSAIDs (oral)
 No concurrent use 1 (reference)  
 Concurrent use 0.41 (0.21, 0.80) 0.008
Proton pump inhibitor drugs (oral)
 No concurrent use 1 (reference)  
 Concurrent use 2.04 (1.35, 3.07) 0.001
  1. CI = confidence interval; GI = gastrointestinal; NSAID = Non-steroidal anti-inflammatory drug; UGIB = upper gastrointestinal bleed.