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Table 3 Response to clinical scenarios

From: Cancer physicians’ attitude towards treatment of the elderly cancer patient in a developed Asian country

Scenario 1: Stage IV Diffuse Large B-cell Non-Hodgkin’s Lymphoma (n = 55)

Treatment options for the older patient

Number

Percentage

R-CHOP1 × 6 + Intrathecal Methotrexate

26

47%

R-CVP2 × 6

21

38%

CHOP3 × 6

4

7%

Palliative radiotherapy

3

6%

Best Supportive Care

1

2%

Treatment options for the younger patient

Number

Percentage

RCHOP × 6 + Intrathecal Methotrexate

45

82%

R-CVP × 6

7

13%

CHOP × 6

3

5%

Palliative radiotherapy

0

0%

Best Supportive Care

0

0%

Factors affecting treatment decision

  

Performance Status

47

85%

Cancer type

37

67%

Cancer stage

20

36%

Patient decision

16

29%

Co-morbidities

15

27%

Age

14

25%

Scenario 2: Stage IIB, Node positive, Hormone receptor positive Breast cancer (n = 53)

Treatment options for the older patient

Number

Percentage

Aromatase inhibitor × 5 years

34

64%

Tamoxifen × 5 years

8

15%

AC4 × 4 → T5 × 12, then endocrine treatment

5

9%

CMF6 × 6, then endocrine treatment

1

2%

FAC7 × 6, then endocrine treatment

1

2%

Others

4

8%

Treatment options for younger patient

Number

Percentage

AC × 4 → T × 12, then endocrine treatment

44

83%

FAC × 6, then endocrine treatment

5

9%

CMF × 6, then endocrine treatment

2

4%

Others

2

4%

Aromatase inhibitor × 5 years

0

0%

Tamoxifen × 5 years

0

0%

Factors affecting treatment decision

Number

Percentage

Cancer Stage

38

72%

Cancer Type

32

60%

Performance Status

25

47%

Age

24

45%

Patient decision

16

30%

Co-morbidities

9

17%

  1. 1R-CHOP: Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone; 2R-CVP: Rituximab, Cyclophosphamide, Vincristine and Prednisolone; 3CHOP: Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone; 4 AC: Doxorubicin and Cyclophosphamide; 5 T: Paclitaxel; 6CMF: Cyclophosphamide, Methotrexate and 5 Fluorouracil; 7FAC: 5 Flurouracil, Doxorubicin and Cyclophosphamide.
  2. Two and four surveys each were incomplete for scenario 1 and scenario 2. Four participants who were haematologists were not familiar with treatment of breast cancer and opted not to fill in the section of the survey pertaining to the case scenario for breast cancer. Similarly, two oncologists opted not to fill in the lymphoma case scenario as they had limited experience treating patients with lymphoma.