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Quality of life in octogenarians with non small cell lung cancer: the strategic role of video assisted thoracic surgery

Background

The aim of the present study was to assess the surgical approach in octogenarians comparing the benefits of video-assisted thoracic surgery (VATS) with the open thoracotomy and analysing early and long term quality of life (QOL) changes.

Materials and methods

We reviewed 42 consecutive octogenarians (mean age 82.3±1.4 years) with a preoperative FEV1 of 1.5 L or less who had undergone pulmonary resection for stage I non-small cell lung cancer (NSCLC). Patients were divided into two groups according to surgical approach (VATS group n=22; thoracotomy group n=20) and their postoperative complications and prognoses were evaluated. Quality of life was assessed using Medical Outcome Study Short-Form 36-item Health Survey (SF-36) just before surgery and at 6 and 12 months postoperatively.

Results

Morbidity rate and postoperative hospital stay were significantly different between VATS and thoracotomy group (p=0.01; p=0.0003, respectively). A worse decrease in thoracotomy vs VATS group was demonstrated in five domains at 6 months, and in all domains at 12 months of SF-36 questionnaire. The thoracotomy group presented a significant reduction in the dyspnoea index, FEV1 and DLCO at both 6 and 12 months.

Conclusions

In octogenarians with NSCLC and compromised pulmonary function the long-term survival justifies the operative treatment, and minimally invasive surgical approach enables surgeons to extend pulmonary resection in these high-risk patients if selected appropriately.

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Correspondence to N D Vicidomini.

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This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Vicidomini, N.D., Guggino, G. & Monaco, G. Quality of life in octogenarians with non small cell lung cancer: the strategic role of video assisted thoracic surgery. BMC Geriatr 11, A65 (2011). https://doi.org/10.1186/1471-2318-11-S1-A65

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Keywords

  • Cell Lung Cancer
  • Small Cell Lung Cancer
  • Postoperative Hospital Stay
  • Pulmonary Resection
  • Open Thoracotomy