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Changes of serum calcium levels after thyroid surgery in the elderly


The reasons of transient hypocalcemia in the elderly, frequent after thyroid surgery, were investigated.

Materials and methods

Serum total calcium and phosphoremia were determined in all patients who underwent thyroidectomy before and after surgery. Beside these, total protein, albumin and parathormone levels were also determined. The daily changes in serum calcemia and protein levels were measured in these patients.


Transient, mild but significant decrease of serum calcium levels was observed after surgery in up to a fifth of patients, while severe hypocalcemia was shown in about 5% of patients. The reduction of calcemia was more evident in elderly patients, with a concomitant reduction of albuminemia. In severe hypocalcemia, in addition to these two findings, decrease of parathormone levels was shown.


We discuss the reasons for these findings, which are more frequently observed in elderly patients and the possible clinical implications to advise them to undergo total thyroidectomy.

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Correspondence to G Patrizi.

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This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Patrizi, G., Federici, S., Fazi, M. et al. Changes of serum calcium levels after thyroid surgery in the elderly. BMC Geriatr 11 (Suppl 1), A41 (2011).

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  • Public Health
  • Calcium
  • Albumin
  • Protein Level
  • Elderly Patient