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Table 4 Effect size and study power analysis of memory performance, global cognitive function and mood in trials of memory strategy training in mild cognitive impairment (MCI)

From: Cognitive and memory training in adults at risk of dementia: A Systematic Review

Citation

Design

Outcome measure

Effect size and 95% confidence Interval

ES > .5 or < -.5

Power of study

> 1 whole number change in test score

Could Type II errors explain lack of significance?

Rapp et al 2002

RCT

Word List immediate T1

.33 (-.58, 1.23)

No

.16

Yes

Yes

  

Word list immediate T2

-1.18 (-2.24, -.11)

Yes

.71

No

 
  

Word list delay T1

.88 (-.07, 1.82)

Yes

.57

Yes

 
  

Word list delay T2

-.36 (-1.36, .64)

No

.16

Yes

 
  

Paragraph immediateT1

-.03 (-.93, .87)

No

.05

Yes

 
  

Paragraph immediate T2

-.54 (- 1.54, .47)

Yes

.26

Yes

 
  

Paragraph delay T1

.38 (-.53, 1.29)

No

.19

Yes

 
  

Paragraph delay T2

-.14 (-1.13, .85)

No

.08

Yes

 
  

Profile of mood states

No data

    

Belleville et al 2006

NRCT

Word list immediate

.78 (-.06,1.63)

Yes

.75

No

Yes

  

Word list delay

.62 (-.22, 1.45)

Yes

.42

Yes

 
  

Text immediate

.09 (-.73, .91)

No

.07

Yes

 
  

Text delay

-.42 (-1.25, .41)

No

.25

No

 
  

Scale of wellbeing

.21 (-.41, .83)

No

.13

Yes

 

Wenisch et al 2007

UCT

Story recall immediate

-.71 (-1.54, -.11)

Yes

Single

Yes

Yes

  

Story recall delay

.09 (-.71, .89)

No

group

No

 

Troyer et al 2008

RCT

Word list T1

.23 (-.82, .35)

No

.18

No

No

  

Word list T2

-.02 (-.58, .62)

No

.06

No

 
  1. ES: Effect size. Relative ES for RCTs and NRCT, and ES for single intervention group in UCT were calculated by authors of this review as described in the methods analysis
  2. Power analysis calculated by the authors of this review as described in the methods analysis
  3. *Significance of effect size contrast from authors' ES analysis
  4. NRCT: Non-randomised controlled trial
  5. UCT: Uncontrolled trial
  6. T1: Immediate
  7. T2: At follow-up
  8. C1: Control Cholinesterase inhibitor
  9. C2: Control
  10. ADAS-Cog: Alzheimer Disease Assessment Scale-Cognitive
  11. NPI: Neuropsychiatry Inventory
  12. MMSE: Mini Mental Status Examination
  13. CVLT: California Verbal Learning Test
  14. RBMT: Rivermead Behavioural Memory Test