| Tertiles of NT-proBNP* |  | Adjusted B (95% CI) |  | ||
---|---|---|---|---|---|---|
 | 1 (n= 26) | 2 (n= 27) | 3 (n= 27) | Pfor trend | Model 1**, adjusted R2= 0.19 Model 2£, adjusted R2= 0.35 | P |
LV dimensions and systolic function | ||||||
LV EDD (mm) | 42 (39 - 51) | 47 (43 - 54) | 51 (45 - 56) | 0.003 | -0.042 (-0.088 - 0.005) | 0.081 |
LV ESD (mm) | 27 (22 - 31) | 28 (27 - 33) | 32 (29 - 37) | 0.002 | 0.034 (-0.030 - 0.099) | 0.29 |
LV Ejection fraction (%) | 69 (60 - 79) | 67 (61 - 72) | 67 (53 - 74) | 0.24 | 0.006 (-0.017 - 0.030) | 0.59 |
LV Mass index (g/m2) | Â | Â | Â | Â | Â | Â |
   Men | 213 (182 - 287) | 236 (177 - 260) | 268 (209 - 372) | 0.068 | 0.003 (0.000 - 0.005) | 0.045 |
   Women | 160 (142 - 190) | 212 (169 - 242) | 213 (160 - 260) | 0.008 |  |  |
Left ventricular diastolic function | ||||||
   E/A | 0.61 (0.51 - 0.70) | 0.72 (0.61 - 0.78) | 0.70 (0.56 - 1.1) | 0.016 | 0.45 (0.026 - 0.87) | 0.038 |
   Left atrial volume (ml) | 30.1 (22.1 - 40.0) | 43.6 (25.6 - 55.3) | 50.3 (33.8 - 73.6) | 0.002 | 0.001 (-0.003 - 0.004) | 0.67 |
Significant heart valvular disease | ||||||
   Mitral regurgitation ≥ moderate | 4 (11%) | 18 (47%) | 16 (42%) | 0.003 | -0.046 (-0.14 - 0.045)$ | 0.32 |
   Aortic regurgitation ≥ moderate | 3 (13%) | 8 (35%) | 12 (52%) | 0.014 | 0.11 (0.002 - 0.21)$ | 0.046 |
   Any aortic stenosis | 7 (50%) | 3 (21%) | 4 (29%) | 0.25 | -0.008 (-0.022 - 0.005)$ | 0.23 |
   Estimated PAP (mmHg) | 33 (26 - 36) | 33 (29 - 37) | 37 (33 - 40) | 0.015 | 0.008 (-0.020 - 0.035)£ | 0.56 |