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Table 3 Cognitive performance at the two waves of data collection (Wave 1 and Wave 2) for each telomere cohort

From: Cognitive performance and leukocyte telomere length in two narrow age-range cohorts: a population study

Cognitive Test

Age Cohort

nat Wave1

Wave 1 Mean ± SD aor Median [IQR]b

nat Wave 2

Wave 2 Mean ± SD aor Median [IQR]b

P-valuec

Immediate recalld

40+

350

8.21 ± 2.18a

351

8.33 ± 2.24a

0.694

 

40+ Men

155

7.69 ± 1.97a

155

7.74 ± 2.05a

0.612

 

40+ Women

195

8.63 ± 2.26a

196

8.80 ± 2.27a

0.665

 

60+

295

7.51 ± 2.13a

293

7.16 ± 1.99a

0.049*

 

60+ Men

158

7.11 ± 2.05a

157

6.86 ± 1.86a

0.307

 

60+ Women

137

7.96 ± 2.14a

136

7.51 ± 2. 08a

0.102

SDMTe

40+

349

61.30 ± 8.79a

350

60.94 ± 8.59a

0.966

 

40+ Men

155

60.70 ± 8.65a

155

60.45 ± 8.67a

0.442

 

40+ Women

194

61.78 ± 8.89a

195

61.32 ± 8.54a

0.416

 

60+

294

51.40 ± 8.00a

293

50.58 ± 8.23a

0.058

 

60+ Men

158

51.42 ± 7.65a

156

50.93 ± 7.71a

0.059

 

60+ Women

136

51.38 ± 8.41a

137

50.19 ± 8.79a

0.292

Simple RT

40+

342

0.224 [0.206-0.245]b

342

0.226 [0.210-0.250]b

0.833

 

40+ Men

150

0.216 [0.200-0.234]b

150

0.223 [0.207-0.243]b

0.553

 

40+ Women

192

0.228 [0.211-0.257]b

192

0.232 [0.213-0.260]b

0.390

 

60+

285

0.238 [0.218-0.267]

285

0.252 [0.228-0.290]b

0..498

 

60+ Men

150

0.234 [0.213-0.254]b

154

0.243 [0.223-0.285]b

0.354

 

60+ Women

135

0.252 [0.221-0.281]b

131

0.260 [0.235-0.302]b

0.117

Choice RT

40+

338

0.283 [0.266-0.306]b

341

0.288 [0.263-0.310]b

0.700

 

40+ Men

150

0.278 [0.262-0.300]b

149

0.278 [0.259-0.302]b

0.784

 

40+ Women

188

0.287 [0.269-0.312]b

192

0.295 [0.265-0.316]b

0.615

 

60+

283

0.314 [0.291-0.334]b

285

0.318 [0.288-0.349]b

0.068

 

60+ Men

149

0.315 [0.289-0.330]b

154

0.317 [0.283-0.345]b

0.989

 

60+ Women

134

0.313 [0.292-0.338]b

131

0.318 [0.294-0.354]b

0.029*

  1. IQR = interquartile range; SD = standard deviation; Immediate recall is from the California Verbal Learning Test; SDMT = Symbol Digit Modalities Test; RT = reaction time; Descriptive statistics are given using the raw data. * p < 0.05
  2. a Mean ± standard deviation
  3. b Median [interquartile range]
  4. c Covariates were Wave1 performance on the relevant cognitive test, age, Spot-the-Word, systolic blood pressure, physical activity, alcohol consumption and where appropriate sex
  5. d For the immediate recall descriptives, outliers (z-scores > +3.29 or < -3.29) were omitted
  6. e For the SDMT descriptives, outliers (z-scores > +3.29 or < -3.29) were omitted