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Physical functioning, physical health and activity

This section covers activities of daily living, frailty, fractures, falls, exercise, posture, gait, hip complications, complications with general bodily functions, e.g. gastroenterological, urological.

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  1. Tai Chi exercise has been reported to enhance physical and mental health in the older adults; however, the mechanism remains elusive.

    Authors: Lili Li, Jingjing Wang, Shaoying Guo, Yangqi Xing, Xiongwen Ke, Yinghao Chen, Yuan He, Shun Wang, Jiayu Wang, Xinwu Cui, Zhihua Wang and Lixu Tang

    Citation: BMC Geriatrics 2021 21:293

    Content type: Research article

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  2. Disturbed sleep places older adults at higher risk for frailty, morbidity, and even mortality. Yet, nursing home routines frequently disturb residents’ sleep through use of noise, light, or efforts to reduce i...

    Authors: A. Lynn Snow, Julia Loup, Robert O. Morgan, Kathy Richards, Patricia A. Parmelee, Rosa R. Baier, Ellen McCreedy, Barbara Frank, Cathie Brady, Liam Fry, Megan McCullough and Christine W. Hartmann

    Citation: BMC Geriatrics 2021 21:281

    Content type: Study protocol

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  3. The risk of progressive declines in skeletal muscle mass and strength, termed sarcopenia, increases with age, physical inactivity and poor diet. The purpose of this study was to explore and compare association...

    Authors: Ewelina Akehurst, David Scott, Juan Peña Rodriguez, Carol Alonso Gonzalez, Jasmaine Murphy, Helen McCarthy, Sandor Dorgo and Alan Hayes

    Citation: BMC Geriatrics 2021 21:276

    Content type: Research article

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  4. Physical fitness is a key component of independent living and healthy ageing. For the measurement of physical fitness in older adults, the Senior Fitness Test is a commonly used tool. The objective of this stu...

    Authors: Birte Marie Albrecht, Imke Stalling and Karin Bammann

    Citation: BMC Geriatrics 2021 21:273

    Content type: Research article

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  5. The Clinical Frailty Scale, which provides a common language about frailty, was recently updated to version 2.0 to cater for its increased use in areas of medicine usually involved in the care and treatment of...

    Authors: Anders Fournaise, Søren Kabell Nissen, Jørgen T. Lauridsen, Jesper Ryg, Christian H. Nickel, Claire Gudex, Mikkel Brabrand, Lone Musaeus Poulsen and Karen Andersen-Ranberg

    Citation: BMC Geriatrics 2021 21:269

    Content type: Correspondence

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  6. There is on one hand sufficient evidence showing strong association between resilience and self-rated successful aging. On the other hand, strength training could contribute the cultivation of resilience among...

    Authors: Pak-Kwong Chung, Chun-Qing Zhang, Yanan Zhao, Ming Yu Claudia Wong and Chun Hu

    Citation: BMC Geriatrics 2021 21:250

    Content type: Study protocol

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  7. For the diagnosis of Sarcopenia, European Working Group on Sarcopenia in Older People (EWGSOP) revised the algorisms in 2019, where they added computed tomography (CT) as an assessment tool not only for quanti...

    Authors: Hiroki Oba, Yasumoto Matsui, Hidenori Arai, Tsuyoshi Watanabe, Hiroki Iida, Takafumi Mizuno, Satoshi Yamashita, Shinya Ishizuka, Yasuo Suzuki, Hideki Hiraiwa and Shiro Imagama

    Citation: BMC Geriatrics 2021 21:239

    Content type: Research article

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  8. Frailty and low handgrip strength (HGS) are associated with adverse outcomes after hip fracture (HF) surgery. We aimed to compare the predictive role of frailty and HGS for adverse outcome in HF patients.

    Authors: Jung-Yeon Choi, Jin-Kak Kim, Kwang-il Kim, Young-Kyun Lee, Kyung-Hoi Koo and Cheol-Ho Kim

    Citation: BMC Geriatrics 2021 21:234

    Content type: Research article

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  9. This study aims to analyze the distribution of serum uric acid (SUA) level based on more than 1000 centenarians and to explore the association with three common diseases including hypertension, diabetes and dy...

    Authors: Fuyin Kou, Shanshan Yang, Shengshu Wang, Miao Liu and Yao He

    Citation: BMC Geriatrics 2021 21:231

    Content type: Research article

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  10. The proportion of older adults is increasing rapidly, and the majority are female. In 2050, the number of persons aged 60 years and over is estimated to reach 2.1 billion worldwide, constituting one-third of t...

    Authors: Hilda Kristin Svensson, Jon Karlsson, Therese Rydberg Sterner, Felicia Ahlner, Ingmar Skoog and Hanna Falk Erhag

    Citation: BMC Geriatrics 2021 21:229

    Content type: Research article

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  12. Falls are one of the major causes of mortality and morbidity in older adults. However, despite adoption of prevention strategies, the number of falls in older adults has not declined. The aim of this study was...

    Authors: Jing Wen Goh, Devinder Kaur Ajit Singh, Normala Mesbah, Anis Afifa Mohd Hanafi and Adlyn Farhana Azwan

    Citation: BMC Geriatrics 2021 21:226

    Content type: Research article

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  13. The incidence of hip fractures are expected to increase in the following years. Hip fracture patients have in addition to their fracture often complex medical problems, which constitute a substantial burden on...

    Authors: Shams Dakhil, Pernille Thingstad, Frede Frihagen, Lars Gunnar Johnsen, Stian Lydersen, Eva Skovlund, Torgeir Bruun Wyller, Olav Sletvold, Ingvild Saltvedt and Leiv Otto Watne

    Citation: BMC Geriatrics 2021 21:208

    Content type: Research article

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  14. The use of technical solutions and conventional mobility supporting aids can support the independence of people into old age in their own homes. However, we found relatively few empirical investigations on the...

    Authors: Deborah Elisabeth Jachan, Ursula Müller-Werdan, Nils Axel Lahmann and Sandra Strube-Lahmann

    Citation: BMC Geriatrics 2021 21:205

    Content type: Research article

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  15. Although previous studies have explored the effect of chronic conditions on physical disability, little is known about the levels and rates of change in physical disability after a chronic condition diagnosis ...

    Authors: Chieh-Ying Chou, Ching-Ju Chiu, Chia-Ming Chang, Chih-Hsing Wu, Feng-Hwa Lu, Jin-Shang Wu and Yi-Ching Yang

    Citation: BMC Geriatrics 2021 21:201

    Content type: Research article

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  16. Interaction of physical activity and overall immune profile is very complex and depends on the intensity, duration and frequency of undertaken physical activity, the exposure to cytomegalovirus (CMV) infection...

    Authors: Anna Tylutka, Barbara Morawin, Artur Gramacki and Agnieszka Zembron-Lacny

    Citation: BMC Geriatrics 2021 21:200

    Content type: Research article

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  17. A healthy lifestyle may prevent disability for older adults. But research to date is limited to a single lifestyle behavior and ignore sex difference in the lifestyle-disability association. This study aimed a...

    Authors: Zaixing Shi, Jianlin Lin, Jian Xiao and Ya Fang

    Citation: BMC Geriatrics 2021 21:188

    Content type: Research article

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  18. Exercise training is crucial for maintaining physical and mental health in aging populations. However, as people participate in structured exercise training, they tend to behaviorally compensate by decreasing ...

    Authors: Tomas Vetrovsky, Dan Omcirk, Jan Malecek, Petr Stastny, Michal Steffl and James J. Tufano

    Citation: BMC Geriatrics 2021 21:179

    Content type: Research article

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  19. Osteoarthritis (OA) is a commonly known prevalent joint disease, with limited therapeutic methods. This study aimed to investigate the functions of miRNA-132 (miR-132) in the modulation of PTEN/PI3K/AKT signal...

    Authors: Wei Zhang, Chengfang Hu, Chi Zhang, Congfeng Luo, Biao Zhong and Xiaowei Yu

    Citation: BMC Geriatrics 2021 21:175

    Content type: Research article

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  20. Iran’s population is aging. Disability is a major public health problem for older adults, not only in Iran but all over the world. The purpose of this study was to investigate the relationship between cardio-m...

    Authors: Kazem Khalagi, Akram Ansarifar, Noushin Fahimfar, Mahnaz Sanjari, Safoora Gharibzdeh, Farshad Sharifi, Gita Shafiee, Ramin Heshmat, Iraj Nabipour, Bagher Larijani and Afshin Ostovar

    Citation: BMC Geriatrics 2021 21:172

    Content type: Research article

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  21. Although previous studies have evaluated risk factors for the incidence of severe infection in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV), the relationship between body mass ...

    Authors: Hirokazu Sugiyama, Makoto Yamaguchi, Takayuki Katsuno, Shiho Iwagaitsu, Hironobu Nobata, Hiroshi Kinashi, Shogo Banno, Masahiko Ando, Yoko Kubo, Takuji Ishimoto and Yasuhiko Ito

    Citation: BMC Geriatrics 2021 21:171

    Content type: Research article

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  22. The purpose of the present study was to investigate the associations between health-related physical fitness performance and overweight/obesity risk among Taiwanese healthy older adults.

    Authors: Chien-Chang Ho, Po-Fu Lee, Hui-Ling Chen, Ching-Yu Tseng, Xin-Yu Hsieh and Chih-Hui Chiu

    Citation: BMC Geriatrics 2021 21:170

    Content type: Research article

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  23. Falls-related injuries are particularly serious for older people, causing pain, reduced community engagement and associated medical costs. Tripping is the leading cause of falls and the current study examined ...

    Authors: Hanatsu Nagano, W. A. Sparrow, Katsuyoshi Mizukami, Eri Sarashina and Rezaul Begg

    Citation: BMC Geriatrics 2021 21:166

    Content type: Research article

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  24. Dementia is a leading cause of death and disability that was declared as one of the greatest health and social care challenges of the twenty-first century. Regular physical activity and exercise have been prop...

    Authors: Joana Carvalho, Flávia Borges-Machado, Duarte Barros, Arnaldina Sampaio, Inês Marques-Aleixo, Lucimere Bohn, Andreia Pizarro, Laetitia Teixeira, José Magalhães and Óscar Ribeiro

    Citation: BMC Geriatrics 2021 21:156

    Content type: Study protocol

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  25. The systemic immune-inflammation index (SII), based on peripheral platelet, neutrophil and lymphocyte counts, has been proven to be a promising prognostic indicator in various diseases. Hip fracture is a commo...

    Authors: Zhi-Cong Wang, Wei Jiang, Xi Chen, Ling Yang, Hong Wang and Yue-Hong Liu

    Citation: BMC Geriatrics 2021 21:155

    Content type: Research article

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  26. Falls incidence rate and comprehensive data on factors that predict occasional and repeated falls from large population-based studies are scarce. In this study, we aimed to determine the incidence of falls and...

    Authors: Theng Choon Ooi, Devinder Kaur Ajit Singh, Suzana Shahar, Nor Fadilah Rajab, Divya Vanoh, Razinah Sharif and Maw Pin Tan

    Citation: BMC Geriatrics 2021 21:154

    Content type: Research article

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  27. Chronic low back pain (CLBP) is a common medical condition in adults over the age of 50. It is associated with severe disability, ranging from physical impairments to psychosocial distress. Since current treat...

    Authors: Lutz Schega, Britta Kaps, Kim-Charline Broscheid, Robert Bielitzki, Martin Behrens, Katharina Meiler, Steffen Drange and Jörg Franke

    Citation: BMC Geriatrics 2021 21:151

    Content type: Study protocol

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  28. Orthostatic hypotension (OH) in geriatric patients frequently involves a component of autonomic failure (AF). The combination of OH with nocturnal hypertension (NHT) is indicative of AF, which is described as ...

    Authors: Siddhartha Lieten, Aziz Debain, Bert Bravenboer and Tony Mets

    Citation: BMC Geriatrics 2021 21:148

    Content type: Case report

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  29. To evaluate the acceptability of handgrip strength, gait speed, quadriceps ultrasound, and Bioelectrical Impedance Analysis (BIA) to older adults conducted during and following hospitalisation.

    Authors: Carly Welch, Carolyn Greig, Tahir Masud and Thomas A. Jackson

    Citation: BMC Geriatrics 2021 21:141

    Content type: Research article

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  30. This study aimed to prospectively analyze the risk factors for new falls and fragility fractures in self-caring elderly patients and to find suitable evaluation tools for community screening and follow-up inte...

    Authors: Jian Zhou, Bo Liu, Ming-Zhao Qin and Jin-Ping Liu

    Citation: BMC Geriatrics 2021 21:116

    Content type: Research article

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  31. The aim of this study was to describe barriers and facilitators for shared decision making (SDM) as experienced by older patients with multiple chronic conditions (MCCs), informal caregivers and health profess...

    Authors: Ruth E. Pel-Littel, Marjolein Snaterse, Nelly Marela Teppich, Bianca M. Buurman, Faridi S. van Etten-Jamaludin, Julia C. M. van Weert, Mirella M. Minkman and Wilma J. M. Scholte op Reimer

    Citation: BMC Geriatrics 2021 21:112

    Content type: Review

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  32. Pneumonia is a major cause of morbidity and mortality in older adults. The role of frailty assessment in older adults with pneumonia is not well defined. Our purpose of the study was to investigate 30-day clin...

    Authors: Chan Mi Park, Wonsock Kim, Hye Chang Rhim, Eun Sik Lee, Jong Hun Kim, Kyung Hwan Cho and Dae Hyun Kim

    Citation: BMC Geriatrics 2021 21:111

    Content type: Research article

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  33. Persons aged ≥ 65 years are currently the world’s fastest growing age group. An important complication of age is the increasing risk of falls. Falls have multifactorial etiology and modifiable risk factors ope...

    Authors: Simone Chantal Gafner, Caroline Henrice Germaine Bastiaenen, Emmanuel Biver, Serge Ferrari and Lara Allet

    Citation: BMC Geriatrics 2021 21:110

    Content type: Study protocol

    Published on:

  34. The interactions between nursing home (NH) staff and their residents are crucial not only for the atmosphere at the NH but also for achieving care goals. In order to test the potential effects of daily physica...

    Authors: S. Vikström, H. K. Grönstedt, T. Cederholm, E. Franzén, G. Faxén-Irving, Å. Seiger and A.-M. Boström

    Citation: BMC Geriatrics 2021 21:109

    Content type: Research article

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  35. The Frailty In Residential Sector over Time (FIRST) Study is a 3-year prospective cohort study investigating the health of residents living in residential aged care services (RACS) in South Australia. The stud...

    Authors: Agathe Daria Jadczak, Leonie Robson, Tina Cooper, J. Simon Bell and Renuka Visvanathan

    Citation: BMC Geriatrics 2021 21:99

    Content type: Research article

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  36. The Lifestyle-integrated Functional Exercise (LiFE) program is an effective but resource-intensive fall prevention program delivered one-to-one in participants’ homes. A recently developed group-based LiFE (gL...

    Authors: Leah Reicherzer, Franziska Kramer-Gmeiner, Sarah Labudek, Carl-Philipp Jansen, Corinna Nerz, Malin J. Nystrand, Clemens Becker, Lindy Clemson and Michael Schwenk

    Citation: BMC Geriatrics 2021 21:93

    Content type: Research article

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  38. Older people are often admitted for rehabilitation to improve walking, yet not everyone improves. The aim of this study was to determine key factors associated with a positive response to hospital-based rehabi...

    Authors: Catherine M Said, Jennifer L McGinley, Cassandra Szoeke, Barbara Workman, Keith D. Hill, Joanne E Wittwer, Michael Woodward, Danny Liew, Leonid Churilov, Julie Bernhardt and Meg E Morris

    Citation: BMC Geriatrics 2021 21:90

    Content type: Research article

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  39. Physical fitness and motor ability are associated with the incidence of locomotive syndrome (LS) in older adults. The relationships between physical fitness and motor ability at a young age to LS risk in later...

    Authors: Shaoshuai Shen, Koya Suzuki, Yoshimitsu Kohmura, Noriyuki Fuku, Yuki Someya and Hisashi Naito

    Citation: BMC Geriatrics 2021 21:89

    Content type: Research article

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  40. The incidence of colorectal cancer (CRC) increases with age. Older patients are a heterogeneous group ranging from fit to frail with various comorbidities. Frail older patients with CRC are at increased risk o...

    Authors: Troels G. Dolin, Marta Mikkelsen, Henrik L. Jakobsen, Tyge Nordentoft, Trine S. Pedersen, Anders Vinther, Bo Zerahn, Kirsten K. Vistisen, Charlotte Suetta, Dorte Nielsen, Julia S. Johansen and Cecilia M. Lund

    Citation: BMC Geriatrics 2021 21:88

    Content type: Study protocol

    Published on:

  42. Age-related sarcopenia meaningfully increases the risks of functional limitations and mortality in the older adults. Although circulating microRNAs (c-miRNAs) are associated with aging-related cellular senesce...

    Authors: Huang-Chun Liu, Der-Sheng Han, Chih-Chin Hsu and Jong-Shyan Wang

    Citation: BMC Geriatrics 2021 21:86

    Content type: Research article

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  43. To investigate whether an exercise intervention using the VIVIFRAIL© protocol has benefits for inflammatory and functional parameters in different frailty status.

    Authors: Marina Petrella, Ivan Aprahamian, Ronei Luciano Mamoni, Carla Fernanda de Vasconcellos Romanini, Natália Almeida Lima, Everson de Cássio Robello, Daniele Lima da Costa, Vinicius Nakajima An, Bianca Nobre Aguirre, Júlia Riccetto Galdeano, Isabela Cunha Fernandes, Salma S. Soleman Hernandez, Matteo Cesari, John E. Morley, Mikel Izquierdo and Richard C. Oude Voshaar

    Citation: BMC Geriatrics 2021 21:83

    Content type: Study protocol

    Published on:

  44. The capacity of postural control is a key factor related to falling in older people, particularly in older women with low back pain (LBP). Cognitive involvement in postural control increases with age. However,...

    Authors: Le Ge, Qiuhua Yu, Chuhuai Wang, Huanjie Huang, Xin Li, Shanshan Zhang and Siyun Zhang

    Citation: BMC Geriatrics 2021 21:82

    Content type: Research article

    Published on:

  45. Maintaining or initiating regular physical activity (PA) is important for successful aging. Technology-based systems may support and stimulate older adults to initiate and persevere in performing PA. The aim o...

    Authors: Els Knippenberg, Annick Timmermans, Steven Palmaers and Annemie Spooren

    Citation: BMC Geriatrics 2021 21:81

    Content type: Research article

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  46. Aspirin is the key treatment in the secondary prevention of atherosclerotic cardiovascular disease. High on-treatment platelet reactivity (HTPR) to aspirin has been reported to partially account for the enhanc...

    Authors: Wenyi Liang, Peng Zhang and Meilin Liu

    Citation: BMC Geriatrics 2021 21:75

    Content type: Research article

    Published on:

  47. Balance control, and specifically balance reactive responses that contribute to maintaining balance when balance is lost unexpectedly, is impaired in older people. This leads to an increased fall risk and inju...

    Authors: Shani Batcir, Yaakov Livne, Rotem Lev Lehman, Shmil Edelman, Lavi Schiller, Omri Lubovsky, Guy Shani, Amir Shapiro and Itshak Melzer

    Citation: BMC Geriatrics 2021 21:71

    Content type: Technical advance

    Published on:

  48. Some types of sedentary behaviors tend to cluster in individuals or groups of older adults. Insight into how these different types of sedentary behavior cluster is needed, as recent research suggests that not ...

    Authors: Sofie Compernolle, Ilse De Bourdeaudhuij, Greet Cardon and Delfien Van Dyck

    Citation: BMC Geriatrics 2021 21:66

    Content type: Research article

    Published on:

  49. Low anterior resection (LAR) is often performed with diverting loop ileostomy (DLI) for anastomotic protection in patients with rectal cancer. We aim to analyze, if older patients are more prone to a decline i...

    Authors: Amal Rhemouga, Stefan Buettner, Wolf O. Bechstein, Guido Woeste and Teresa Schreckenbach

    Citation: BMC Geriatrics 2021 21:65

    Content type: Research article

    Published on:

  50. Osteopontin plays critical roles in osteoarthritis (OA) by regulating the functions of osteoclasts. It is known that osteopontin can induce the expression of lncRNA HOX transcript antisense RNA (HOTAIR), indic...

    Authors: Quanzhi Liang, Ailijiang Asila, Yingjie Deng, Jun Liao, Zhenfeng Liu and Rui Fang

    Citation: BMC Geriatrics 2021 21:57

    Content type: Research article

    Published on:

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