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Neurology, stroke and cognition

Section edited by Pieter Jelle Visser

This section considers manuscripts on all neurological topics. Including: Alzheimer’s, cognition, stroke, dementia, wandering behaviours.

Page 2 of 3

  1. Content type: Research Article

    Reduced level of arousal is commonly observed in medical admissions and may predict in-hospital mortality. Delirium and reduced level of arousal are closely related. We systematically reviewed and conducted a ...

    Authors: Amy Todd, Samantha Blackley, Jennifer K. Burton, David J. Stott, E. Wesley Ely, Zoë Tieges, Alasdair M. J. MacLullich and Susan D. Shenkin

    Citation: BMC Geriatrics 2017 17:283

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  2. Content type: Research Article

    Anxiety and depression are common in Parkinson disease and both are important determinants of quality of life in patients. Several risk factors are identified but few research have investigated general and Par...

    Authors: Shi-Shuang Cui, Juan-Juan Du, Rao Fu, Yi-Qi Lin, Pei Huang, Ya-Chao He, Chao Gao, Hua-Long Wang and Sheng-Di Chen

    Citation: BMC Geriatrics 2017 17:270

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  3. Content type: Research Article

    Dementia imposes a high burden of disease worldwide. Recent epidemiological studies in European community samples are scarce. In Portugal, community prevalence data is very limited. The 10/66 Dementia Research...

    Authors: Manuel Gonçalves-Pereira, Ana Cardoso, Ana Verdelho, Joaquim Alves da Silva, Manuel Caldas de Almeida, Alexandra Fernandes, Cátia Raminhos, Cleusa P. Ferri, A. Matthew Prina, Martin Prince and Miguel Xavier

    Citation: BMC Geriatrics 2017 17:261

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  4. Content type: Research Article

    Previous studies reported mixed results regarding the association between cognition and body weight in late life. We evaluated the relationships between cognitive function and body composition among community-...

    Authors: Hye-Mi Noh, Sohee Oh, Hong Ji Song, Eun Young Lee, Jin-Young Jeong, Ohk-Hyun Ryu, Kyung-Soon Hong and Dong-Hyun Kim

    Citation: BMC Geriatrics 2017 17:259

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  5. Content type: Research Article

    The Doloplus-2 is a pain assessment scale for assessing pain in older adults with cognitive impairment. It is used in clinical practice and research. However, evidence for its measurement properties, feasibili...

    Authors: Hanne Marie Rostad, Inger Utne, Ellen Karine Grov, Martine Puts and Liv Halvorsrud

    Citation: BMC Geriatrics 2017 17:257

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  6. Content type: Research article

    Decreased circulating tryptophan (Trp) levels are frequently observed in elderly patients with neurodegenerative disease including Alzheimer’s disease. Trp may serve as a potential biomarker for monitoring dis...

    Authors: Yusuke Adachi, Yoshiki Shimodaira, Hidehiro Nakamura, Akira Imaizumi, Maiko Mori, Yoko Kageyama, Yasushi Noguchi, Asuka Seki, Yuki Okabe, Yuko Miyake, Kaori Ono and Shu Kumagai

    Citation: BMC Geriatrics 2017 17:239

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  7. Content type: Research Article

    Type 2 Diabetes (T2D) is associated with increased risk of dementia. We aimed to determine the feasibility of a randomised controlled trial (RCT) examining the efficacy of exercise on cognition and brain struc...

    Authors: M. L. Callisaya, R. M. Daly, J. E. Sharman, D. Bruce, T. M. E. Davis, T. Greenaway, M. Nolan, R. Beare, M. G. Schultz, T. Phan, L. C. Blizzard and V. K. Srikanth

    Citation: BMC Geriatrics 2017 17:237

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  8. Content type: Research Article

    Few studies have addressed the relationship between dementia and crime. We conducted a study of persons who got a primary or secondary diagnosis of dementia or cognitive disorder in a forensic psychiatric exam...

    Authors: Anette Ekström, Marianne Kristiansson and Karin Sparring Björkstén

    Citation: BMC Geriatrics 2017 17:219

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  9. Content type: Research Article

    Atrial fibrillation (AF) is often asymptomatic and undiagnosed until an ischaemic stroke occurs. An irregular pulse is a key manifestation of AF. We assessed whether pulse self-palpation is feasible in screeni...

    Authors: Jussi Jaakkola, Raine Virtanen, Tuija Vasankari, Marika Salminen and K.E. Juhani Airaksinen

    Citation: BMC Geriatrics 2017 17:218

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  10. Content type: Research Article

    The cerebrospinal fluid (CSF) biomarkers amyloid β (Aβ), phospho tau (P-tau) and total tau (T-tau) are used increasingly to support a clinical diagnosis of Alzheimer’s disease. The diagnostic power of these bi...

    Authors: Anne-Brita Knapskog, Rannveig Sakshaug Eldholm, Anne Braekhus, Knut Engedal and Ingvild Saltvedt

    Citation: BMC Geriatrics 2017 17:210

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  11. Content type: Research Article

    The Alzheimer’s disease (AD) brain displays atrophy with amyloid-β (Aβ) and tau deposition, whereas decreased Aβ42 and increased tau are measured in cerebrospinal fluid (CSF). The aim of this study was to rela...

    Authors: V. Velickaite, V. Giedraitis, K. Ström, I. Alafuzoff, H. Zetterberg, L. Lannfelt, L. Kilander, E-M. Larsson and M. Ingelsson

    Citation: BMC Geriatrics 2017 17:208

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  12. Content type: Research Article

    Behavioral and psychological symptoms of dementia (BPSD) are common and varied in the elderly. The aim of the current study was to explore associations between BPSD and dysphoric symptoms at different levels o...

    Authors: Agnes Lindbo, Maria Gustafsson, Ulf Isaksson, Per-Olof Sandman and Hugo Lövheim

    Citation: BMC Geriatrics 2017 17:206

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  13. Content type: Case report

    Elderly patients have a long list of differentials for causes of acute confusion and altered consciousness levels, including infectious agents. In addition, elderly, retired patients often have more time to tr...

    Authors: James Veater, Farhan Mehedi, Chee Kay Cheung, Laura Nabarro, Jane Osborne, Nicholas Wong, Martin Wiselka and Julian W Tang

    Citation: BMC Geriatrics 2017 17:193

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  14. Content type: Research Article

    New or increased impairments may develop several decades after an acute poliomyelitis infection. These new symptoms, commonly referred to as late effects of polio (LEoP), are characterised by muscular weakness...

    Authors: Catharina Sjödahl Hammarlund, Jan Lexell and Christina Brogårdh

    Citation: BMC Geriatrics 2017 17:179

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  15. Content type: Research Article

    Physical activity plays a pivotal role in the development of disability and may modify the negative effect of vascular risk factors on progression of both cardio and cerebrovascular disorders. The aim of this ...

    Authors: Anna F. Pettersson, Lars-Olof Wahlund, Lena Bronge, Elisabeth Olsson, Kaarina Amberla, Hansjoerg Baezner and Milita Crisby

    Citation: BMC Geriatrics 2017 17:142

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  16. Content type: Research Article

    Worldwide, the population is aging and the number of individuals diagnosed with dementia is rising rapidly. Currently, there are no effective pharmaceutical cures. Hence, identifying lifestyle approaches that ...

    Authors: Lisanne F. ten Brinke, Jennifer C. Davis, Cindy K. Barha and Teresa Liu-Ambrose

    Citation: BMC Geriatrics 2017 17:139

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  17. Content type: Research Article

    To determine the association between amyloid-beta (Aβ) plaque deposition and changes in global cognition, executive functions, information processing speed, and falls risk over a 12-month period in older adult...

    Authors: Elizabeth Dao, John R. Best, Ging-Yuek Robin Hsiung, Vesna Sossi, Claudia Jacova, Roger Tam and Teresa Liu-Ambrose

    Citation: BMC Geriatrics 2017 17:133

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  18. Content type: Research article

    Alzheimer’s disease (AD) is the most common cause of dementia and early and accurate diagnosis is important. Olfactory dysfunction is an early sign of AD. The contribution by test of olfactory function has bee...

    Authors: Ib Thrane Christensen, Elna-Marie Larsson, Ida E. Holm, Ole B.F. Nielsen and Stig Andersen

    Citation: BMC Geriatrics 2017 17:129

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  19. Content type: Research Article

    One of the most common uses of the Internet is to search for health-related information. Although scientific evidence pertaining to cognitive health promotion has expanded rapidly in recent years, it is unclea...

    Authors: P.V. Hunter, M. Delbaere, M. E. O’Connell, A. Cammer, J. X. Seaton, T. Friedrich and F. Fick

    Citation: BMC Geriatrics 2017 17:125

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  20. Content type: Study protocol

    Delirium is common, affecting at least 20% of older hospital inpatients. It is widely accepted that delirium is associated with dementia but the degree of causation within this relationship is unclear. Previou...

    Authors: Sarah J. Richardson, Daniel H.J. Davis, Blossom Stephan, Louise Robinson, Carol Brayne, Linda Barnes, Stuart Parker and Louise M. Allan

    Citation: BMC Geriatrics 2017 17:98

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  21. Content type: Study protocol

    To date there is no cure or an effective disease-modifying drug to treat dementia. Available acetylcholine-esterase inhibiting drugs or memantine only produce small benefits on cognitive and behavioural functi...

    Authors: E. G. A. Karssemeijer, W. J. R. Bossers, J. A. Aaronson, R. P. C. Kessels and M. G. M. Olde Rikkert

    Citation: BMC Geriatrics 2017 17:73

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  22. Content type: Research Article

    The prevalence of psychotropic drug (PTD) use in NH residents is high, but few have explored prevalence and persistency in PTD in NH residents and factors associated with persistency. This at the same time as ...

    Authors: Anne-Sofie Helvik, Jūratė Šaltytė Benth, Bei Wu, Knut Engedal and Geir Selbæk

    Citation: BMC Geriatrics 2017 17:52

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  23. Content type: Research Article

    Sunlight exposure and high vitamin D status have been hypothesised to reduce the risk of developing dementia. The objective of our research was to determine whether lack of sunlight and hypovitaminosis D over ...

    Authors: Isolde Sommer, Ursula Griebler, Christina Kien, Stefanie Auer, Irma Klerings, Renate Hammer, Peter Holzer and Gerald Gartlehner

    Citation: BMC Geriatrics 2017 17:16

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  24. Content type: Study protocol

    Frequent hospitalization and permanent nursing home placement not only affect the well-being of persons with dementia, but also place great financial strain on society. Therefore, it is important to create eff...

    Authors: Sophie Vandepitte, Nele Van Den Noortgate, Koen Putman, Sofie Verhaeghe and Lieven Annemans

    Citation: BMC Geriatrics 2016 16:207

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  25. Content type: Research Article

    Alzheimer’s disease (AD), the commonest cause of dementia, represents a significant cost to UK society. This analysis describes resource utilisation, costs and clinical outcomes in non-institutionalised patien...

    Authors: Alan Lenox-Smith, Catherine Reed, Jeremie Lebrec, Mark Belger and Roy W. Jones

    Citation: BMC Geriatrics 2016 16:195

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  26. Content type: Research Article

    The discrepancy between the number of admissions and the allocation of hospital beds means that many patients admitted to hospital can be placed in units or wards other than that which specialise in the patien...

    Authors: Lua Perimal-Lewis, Clare Bradley, Paul H. Hakendorf, Craig Whitehead, Louise Heuzenroeder and Maria Crotty

    Citation: BMC Geriatrics 2016 16:190

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  27. Content type: Research Article

    Bilingualism may protect against cognitive aging and delay the onset of dementia. However, studies comparing monolinguals and bilinguals on such metrics have produced inconsistent results complicated by confou...

    Authors: Claudia Padilla, Mario F. Mendez, Elvira E. Jimenez and Edmond Teng

    Citation: BMC Geriatrics 2016 16:189

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  28. Content type: Research Article

    Subjective cognitive decline (SCD), i.e., the self-perceived feeling of worsening cognitive function, may be the first notable syndrome of preclinical Alzheimer’s disease and other dementias. However, not all ...

    Authors: Susanne Roehr, Arno Villringer, Matthias C. Angermeyer, Tobias Luck and Steffi G. Riedel-Heller

    Citation: BMC Geriatrics 2016 16:180

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  29. Content type: Research article

    Few studies have investigated factors associated with depression among elderly people with and without stroke concurrently, using identical settings, procedures and study variables. The aim was to investigate ...

    Authors: Carl Hörnsten, Hugo Lövheim, Peter Nordström and Yngve Gustafson

    Citation: BMC Geriatrics 2016 16:174

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  30. Content type: Research Article

    Most patients with dementia or cognitive impairment receive care from family members, often untrained for this challenging role. Caregivers may not access publicly available caregiving information, and caregiv...

    Authors: Kendra Peterson, Howard Hahn, Amber J. Lee, Catherine A. Madison and Alireza Atri

    Citation: BMC Geriatrics 2016 16:164

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  31. Content type: Research Article

    Older people are commonly prescribed multiple medications, including medications with anticholinergic effects. Polypharmacy and anticholinergic medications may be risk factors for the development of delirium.

    Authors: Hannah C. Moorey, Sebastian Zaidman and Thomas A. Jackson

    Citation: BMC Geriatrics 2016 16:162

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  32. Content type: Research Article

    Age increases the risk of mortality and poor prognosis following stroke. The benefit of intravenous thrombolysis in very old patients remains uncertain. The purpose of the study was to evaluate the efficacy an...

    Authors: S. Sagnier, P. Galli, M. Poli, S. Debruxelles, P. Renou, S. Olindo, F. Rouanet and I. Sibon

    Citation: BMC Geriatrics 2016 16:156

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  33. Content type: Research Article

    To examine whether delirium in hip fracture patients was associated with changes in the levels of amino acids and/or monoamine metabolites in cerebrospinal fluid (CSF) and serum.

    Authors: Leiv Otto Watne, Ane-Victoria Idland, Durk Fekkes, Johan Raeder, Frede Frihagen, Anette Hylen Ranhoff, Farrukh Abbas Chaudhry, Knut Engedal, Torgeir Bruun Wyller and Bjørnar Hassel

    Citation: BMC Geriatrics 2016 16:149

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  34. Content type: Research article

    There are knowledge gaps about the life situation for people ageing with Parkinson’s disease (PD), with virtually no understanding of home and health dynamics. Therefore, the aim of the present study was to ex...

    Authors: Maria H. Nilsson, Susann Ullén, Henrik Ekström and Susanne Iwarsson

    Citation: BMC Geriatrics 2016 16:146

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  35. Content type: Research Article

    Assisting a person with dementia can lead to significant carer burden and possible negative outcomes for the person. Using the Delphi method, this study developed expert consensus guidelines for how family and...

    Authors: K. S. Bond, A. F. Jorm, B. A. Kitchener, C. M. Kelly and K. J. Chalmers

    Citation: BMC Geriatrics 2016 16:129

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  36. Content type: Research article

    There are various definitions and diagnostic criteria for dementia, leading to discrepancies in case ascertainment in both clinical practice and research. We reviewed the different definitions, approaches and ...

    Authors: Rebecca Palm, Saskia Jünger, Sven Reuther, Christian G. G. Schwab, Martin N. Dichter, Bernhard Holle and Margareta Halek

    Citation: BMC Geriatrics 2016 16:78

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  37. Content type: Research article

    Existing everyday technology as well as potential future technology may offer both challenges and possibilities in the everyday occupations of persons with cognitive decline. To meet their wishes and needs, th...

    Authors: Annicka Hedman, Eva Lindqvist and Louise Nygård

    Citation: BMC Geriatrics 2016 16:73

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  38. Content type: Research article

    This project Smart Assisted Living involving Informal careGivers++ (SALIG) intends to develop an ICT-based device for persons with cognitive impairment combined with remote support possibilities for significan...

    Authors: Inga-Lill Boman, Ann-Christine Persson and Aniko Bartfai

    Citation: BMC Geriatrics 2016 16:61

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  39. Content type: Research article

    Muscle wasting and obesity may complicate the post-stroke trajectory. We investigated the relationships between nutritional status, body composition, and mobility one to 3 years after stroke.

    Authors: Birgit Vahlberg, Lena Zetterberg, Birgitta Lindmark, Karin Hellström and Tommy Cederholm

    Citation: BMC Geriatrics 2016 16:48

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  40. Content type: Research article

    We analyzed the associations between diabetes and cognitive impairment (CI) and dependence in a population of patients 65 years or older.

    Authors: Emiliano Rodríguez-Sánchez, Sara Mora-Simón, María C. Patino-Alonso, Diana Pérez-Arechaederra, José I. Recio-Rodríguez, Manuel A. Gómez-Marcos, Luis F. Valero-Juan and Luis García-Ortiz

    Citation: BMC Geriatrics 2016 16:33

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  41. Content type: Research article

    The neural mechanisms underlying the restorative effects of cognitive training on aging brains remain unclear. To address this issue, we examined the relationship between changes in spontaneous brain activity ...

    Authors: Ting Li, Ye Yao, Yan Cheng, Bing Xu, Xinyi Cao, David Waxman, Wei Feng, Yuan Shen, Qingwei Li, Jijun Wang, Wenyuan Wu, Chunbo Li and Jianfeng Feng

    Citation: BMC Geriatrics 2016 16:12

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  42. Content type: Research article

    The interactive effect between diabetes and impaired kidney function on cognitive impairment in older adults has not yet been reported. The aim of this study was to investigate the association of diabetes and ...

    Authors: Zhaoxue Yin, Zhongrui Yan, Yajun Liang, Hui Jiang, Chuanzhu Cai, Aiqin Song, Lei Feng and Chengxuan Qiu

    Citation: BMC Geriatrics 2016 16:7

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  43. Content type: Research article

    Frailty and cognitive impairment are seemingly distinct syndromes, but have a shared vulnerability to stress in older adults, resulting in poorer outcomes. Although there has been recent interest in cognitive ...

    Authors: Mei Sian Chong, Laura Tay, Mark Chan, Wee Shiong Lim, Ruijing Ye, Eng King Tan and Yew Yoong Ding

    Citation: BMC Geriatrics 2015 15:175

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  44. Content type: Research article

    Current research has established obesity as one of the main modifiable risk factors for cognitive impairment. However, evidence on the relationships of total and regional body composition measures as well as s...

    Authors: Efstathios Papachristou, Sheena E. Ramsay, Lucy T. Lennon, Olia Papacosta, Steve Iliffe, Peter H. Whincup and S. Goya Wannamethee

    Citation: BMC Geriatrics 2015 15:172

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  45. Content type: Research article

    We have previously described the development of the Identification and Intervention for Dementia in Elderly Africans (IDEA) cognitive screen for use in populations with low levels of formal education. The IDEA...

    Authors: Stella-Maria Paddick, William K Gray, Luqman Ogunjimi, Bingileki lwezuala, Olaide Olakehinde, Aloyce Kisoli, John Kissima, Godfrey Mbowe, Sarah Mkenda, Catherine L Dotchin, Richard W Walker, Declare Mushi, Cecilia Collingwood and Adesola Ogunniyi

    Citation: BMC Geriatrics 2015 15:53

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  46. Content type: Research article

    Mobility problems and cognitive deficits related to transferring or moving persons suffering from dementia are associated with dependency. Physical assistance provided by staff is an important component of res...

    Authors: Charlotta Thunborg, Petra von Heideken Wågert, Eva Götell, Ann-Britt Ivarsson and Anne Söderlund

    Citation: BMC Geriatrics 2015 15:6

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