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Neurology, stroke and cognition

Section edited by Pieter Jelle Visser

This section considers manuscripts on all neurological topics. Including: Alzheimer’s, cognition, stroke, dementia, wandering behaviours.

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  2. Physical and social environments may influence cognition health in older adults. However, evidence regarding physical and social environments linked to dementia is lacking, especially in Asia. This study aims ...

    Authors: Chih-Ching Liu, Yu Sun, Shiann-Far Kung, Hsien-Wen Kuo, Nuan-Ching Huang, Chung-Yi Li and Susan C. Hu

    Citation: BMC Geriatrics 2020 20:226

    Content type: Research article

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  3. Hematologic malignancies can spread to the central nervous system (CNS), either as focal lesions or as leptomeningeal disease. Marginal zone lymphoma (MZL) is a low-grade non-Hodgkin lymphoma and generally pre...

    Authors: Lisa Dreessen, Nicolas Maréchal, Michel Verheyden, Ann De Becker, Kristin Jochmans, Tim Vanderhasselt, Bert Bravenboer and Ingo Beyer

    Citation: BMC Geriatrics 2020 20:213

    Content type: Case report

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  5. Ocular imaging receives much attention as a source of potential biomarkers for dementia. In the present study, we analyze these ocular biomarkers in cognitively impaired and healthy participants in a populatio...

    Authors: Jacoba A. van de Kreeke, Nienke Legdeur, Maryam Badissi, H. Ton Nguyen, Elles Konijnenberg, Jori Tomassen, Mara ten Kate, Anouk den Braber, Andrea B. Maier, H. Stevie Tan, Frank D. Verbraak and Pieter Jelle Visser

    Citation: BMC Geriatrics 2020 20:155

    Content type: Research article

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  6. This study explored the effects of physical activity and sedentary behaviour on the decline of cognitive ability among the elderly. To compensate for the limitations of self-reported physical activity, objecti...

    Authors: Zhi-jian Wu, Zhu-ying Wang, Bing-qian Hu, Xu-hui Zhang, Fan Zhang, Hou-lei Wang and Fang-hui Li

    Citation: BMC Geriatrics 2020 20:149

    Content type: Research article

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  7. The relationship between frailty and dementia is unclear and there are very few population-based studies regarding this issue in China. The purpose of this study is to estimate the association between frailty ...

    Authors: Minghui Li, Yueqin Huang, Zhaorui Liu, Rui Shen, Hongguang Chen, Chao Ma, Tingting Zhang, Shuran Li and Martin Prince

    Citation: BMC Geriatrics 2020 20:138

    Content type: Research article

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  8. Physical activity may decrease the risk of dementia; however, previous cohort studies seldom investigated the different types of physical activity and household activities. Our objective was to analyze the lin...

    Authors: Caroline Dupré, Bienvenu Bongue, Catherine Helmer, Jean François Dartigues, David Hupin, Frédéric Roche, Claudine Berr and Isabelle Carrière

    Citation: BMC Geriatrics 2020 20:132

    Content type: Research article

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  9. The implementation of evidence-based interventions for people with dementia is complex and challenging. However, successful implementation might be a key element to ensure evidence-based practice and high qual...

    Authors: Melanie Karrer, Julian Hirt, Adelheid Zeller and Susi Saxer

    Citation: BMC Geriatrics 2020 20:127

    Content type: Research article

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  10. Motoric cognitive risk syndrome (MCR) is a newly proposed predementia syndrome incorporating subjective cognitive complaints and slow gait. Previous studies have reported that subjective cognitive complaints a...

    Authors: Shanshan Shen, Xingkun Zeng, Liyu Xu, Lingyan Chen, Zixia Liu, Jiaojiao Chu, Yinghong Yang, Xiushao Wu and Xujiao Chen

    Citation: BMC Geriatrics 2020 20:110

    Content type: Research article

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  11. Antimuscarinics are often used for treatment of overactive bladder (OAB), but exposure to medications such as antimuscarinics that have anticholinergic properties has been linked to adverse cognitive effects. ...

    Authors: Tomas L. Griebling, Noll L. Campbell, Jeffrey Mangel, David Staskin, Sender Herschorn, Dina Elsouda and Carol R. Schermer

    Citation: BMC Geriatrics 2020 20:109

    Content type: Research article

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  12. Research in the area of public stigma and Alzheimer’s disease (AD) is limited to examining stigmatic beliefs towards persons aged 65 and over (i.e., persons with late-onset dementia). The aim of the present st...

    Authors: Perla Werner, Lilach Raviv-Turgeman and Patrick W. Corrigan

    Citation: BMC Geriatrics 2020 20:104

    Content type: Research article

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  13. There remains a lack of large-scale clinical studies of cognitive impairment that aim to increase diagnostic and prognostic accuracy as well as validate previous research findings. The MemClin project will ama...

    Authors: Urban Ekman, Daniel Ferreira, J-Sebastian Muehlboeck, John Wallert, Anna Rennie, Maria Eriksdotter, Lars-Olof Wahlund and Eric Westman

    Citation: BMC Geriatrics 2020 20:93

    Content type: Research article

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  14. The ability to walk and perform cognitive tasks simultaneously is a key aspect of daily life. Performance declines in these dual-tasks may be associated with early signs of neurodegenerative disease and increa...

    Authors: David A. Raichlen, Pradyumna K. Bharadwaj, Lauren A. Nguyen, Mary Kathryn Franchetti, Erika K. Zigman, Abigail R. Solorio and Gene E. Alexander

    Citation: BMC Geriatrics 2020 20:83

    Content type: Research article

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  15. People with dementia often require full-time caregivers especially in the later stages of their condition. People with dementia and caregivers’ access to reliable information on dementia is essential as it may...

    Authors: Aijia Soong, Shu Ting Au, Bhone Myint Kyaw, Yin Leng Theng and Lorainne Tudor Car

    Citation: BMC Geriatrics 2020 20:61

    Content type: Research article

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  16. All individuals with severe dementia should be offered careful hand feeding. However, under certain circumstances, people with severe dementia have a feeding tube placed. In Taiwan, tube feeding rate in dement...

    Authors: Hsiao-Hui Chou, Meng-Ting Tsou and Lee-Ching Hwang

    Citation: BMC Geriatrics 2020 20:60

    Content type: Research article

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  17. There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s...

    Authors: Vincent Mubangizi, Samuel Maling, Celestino Obua and Alexander C. Tsai

    Citation: BMC Geriatrics 2020 20:48

    Content type: Research article

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  18. With the fast-paced aging and increasing digitalization of society, there has been a growing interest in the effect of mobile device use on cognitive function and depression in older adults. However, research ...

    Authors: Lu Lin, Xiu-Chen Jing, Shu-Jiao Lv, Jing-Hong Liang, Li Tian, Hui-Ling Li, Martine Puts and Yong Xu

    Citation: BMC Geriatrics 2020 20:41

    Content type: Research article

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  19. To identify the incidence of, risk factors for, and outcomes associated with postoperative delirium (POD) in older adult patients who underwent noncardiac surgery.

    Authors: Arissara Iamaroon, Titima Wongviriyawong, Patumporn Sura-arunsumrit, Nattikan Wiwatnodom, Nichakarn Rewuri and Onuma Chaiwat

    Citation: BMC Geriatrics 2020 20:40

    Content type: Research article

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  20. Cognition has been related with gait speed in older adults; however, studies involving the oldest age group, where many have mobility disability and cognitive impairment, are few. The aim was to investigate th...

    Authors: Jerry Öhlin, Anders Ahlgren, Robert Folkesson, Yngve Gustafson, Håkan Littbrand, Birgitta Olofsson and Annika Toots

    Citation: BMC Geriatrics 2020 20:34

    Content type: Research article

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  21. Cognitive impairment is a major contributor to mortality among the elderly. However, the relationship between cognitive impairment evaluated by educational levels and mortality and the trend between cognitive ...

    Authors: Jun Duan, Yue-Bin Lv, Xiang Gao, Jin-Hui Zhou, Virginia Byers Kraus, Yi Zeng, Hong Su and Xiao-Ming Shi

    Citation: BMC Geriatrics 2020 20:29

    Content type: Research article

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  22. Stroke is a highly prevalent disease among older people and can have a major impact on daily functioning and quality of life. When community-dwelling older people are hospitalized due to stroke, discharge to a...

    Authors: Tom P. M. M. Vluggen, Jolanda C. M. van Haastregt, Frans E. S. Tan, Gertrudis I. J. M. Kempen, Jos M. G. A. Schols and Jeanine A. Verbunt

    Citation: BMC Geriatrics 2020 20:25

    Content type: Research article

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  23. Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focuse...

    Authors: Werayuth Srithumsuk, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Yuya Akagi, Nonglak Klinpudtan, Eri Kiyoshige, Kayo Godai, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Madoka Ogawa, Hiroki Inagaki…

    Citation: BMC Geriatrics 2020 20:24

    Content type: Research article

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  24. Studies have shown an association between lower urinary tract symptoms (LUTS) and an increased risk of dementia. Whether anticholinergic use contributes to the development of dementia in patients with LUTS rem...

    Authors: Yi-Chi Wang, Yung-Liang Chen, Chun-Che Huang, Chung-Han Ho, Yu-Tung Huang, Ming-Ping Wu, Ming-Jung Ou, Chiu-Hsien Yang and Ping-Jen Chen

    Citation: BMC Geriatrics 2019 19:380

    Content type: Research article

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  25. Stroke patients have increased risks of falls. We examined national registry data to evaluate the association between post-stroke functional level and the risk of low falls among post-stroke patients.

    Authors: Wycliffe E. Wei, Deirdre A. De Silva, Hui Meng Chang, Jiali Yao, David B. Matchar, Sherry H. Y. Young, Siew Ju See, Gek Hsiang Lim, Ting Hway Wong and Narayanaswamy Venketasubramanian

    Citation: BMC Geriatrics 2019 19:373

    Content type: Research article

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  26. We investigated the association between trajectories of verbal episodic memory and burden of cardiovascular risk factors in middle-aged and older community-dwellers.

    Authors: Beatriz Olaya, Maria Victoria Moneta, Martin Bobak, Josep Maria Haro and Panayotes Demakakos

    Citation: BMC Geriatrics 2019 19:337

    Content type: Research article

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  27. C677T point mutation in methylenetetrahydrofolate reductase (MTHFR) gene have been found to be associated with ischemic stroke in general population, while the results seem inconsistent. We aim to assess the a...

    Authors: Guilin Chang, Zheng Kuai, Jia Wang, Jiayu Wu, Kan Xu, Ying Yuan and Yu Hu

    Citation: BMC Geriatrics 2019 19:331

    Content type: Research article

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  28. Our objective was to characterize the relationship of anemia and hemoglobin concentrations with cross-sectional cognitive functions and changes in cognitive functions over 2 years in a large sample of Chinese ...

    Authors: Tingting Qin, Mingming Yan, Zhen Fu, Yating Song, Wanrong Lu, A’dan Fu and Ping Yin

    Citation: BMC Geriatrics 2019 19:305

    Content type: Research article

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  29. People with dementia describe experiences of loss that threaten their autonomy and ability to contribute to society. They often have difficulties with orientation, loss of roll function, and fear about the fut...

    Authors: Guro Hanevold Bjørkløf, Anne-Sofie Helvik, Tanja Louise Ibsen, Elisabeth Wiken Telenius, Ellen Karine Grov and Siren Eriksen

    Citation: BMC Geriatrics 2019 19:295

    Content type: Research article

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  30. The prevention of pneumonia is critical for patients with acute ischaemic stroke (AIS). The six subscales in the Braden Scale seem to be related to the occurrence of pneumonia. We aimed to evaluate the feasibi...

    Authors: Yunlong Ding, Yazhou Yan, Jiali Niu, Yanrong Zhang, Zhiqun Gu, Ping Tang and Yan Liu

    Citation: BMC Geriatrics 2019 19:259

    Content type: Research article

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  31. Impaired cognition is a major risk factor for perioperative delirium. It is essential to provide good pain control in patients with hip fractures and especially important in patients with severely impaired cog...

    Authors: Pär Wennberg, Margareta Möller, Johan Herlitz and Elisabeth Kenne Sarenmalm

    Citation: BMC Geriatrics 2019 19:252

    Content type: Research article

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  33. Internationally, there is a drive to involve patients and the public in health research, due to recognition that patient and public involvement (PPI) may increase the impact and relevance of health research. T...

    Authors: Jahanara Miah, Piers Dawes, Steven Edwards, Iracema Leroi, Bella Starling and Suzanne Parsons

    Citation: BMC Geriatrics 2019 19:220

    Content type: Research article

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  34. In the absence of treatment options, the WHO emphasizes the identification of effective prevention strategies as a key element to counteract the dementia epidemic. Regarding the complex nature of dementia, tri...

    Authors: Andrea Zülke, Tobias Luck, Alexander Pabst, Wolfgang Hoffmann, Jochen René Thyrian, Jochen Gensichen, Hanna Kaduszkiewicz, Hans-Helmut König, Walter E. Haefeli, David Czock, Birgitt Wiese, Thomas Frese, Susanne Röhr and Steffi G. Riedel-Heller

    Citation: BMC Geriatrics 2019 19:203

    Content type: Study protocol

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  35. The identification of factors associated with functional impairment, in particular those which are potentially modifiable, may help to delay the advanced stages of functional dependence in patients with neuroc...

    Authors: Virginie Dauphinot, Claire Moutet, Isabelle Rouch, Mathieu Verdurand, Christelle Mouchoux, Floriane Delphin-Combe, Sylvain Gaujard and Pierre Krolak-Salmon

    Citation: BMC Geriatrics 2019 19:191

    Content type: Study protocol

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  36. Dementia is a syndrome, with a wide range of symptoms. It is important to have a timely diagnosis during the disease course to reduce the risk of medication errors, enable future care planning for the patient ...

    Authors: Connie Lethin, Ingalill Rahm Hallberg, Anna Renom Guiteras, Hilde Verbeek, Kai Saks, Minna Stolt, Adelaida Zabalegui, Maria Soto-Martin and Christer Nilsson

    Citation: BMC Geriatrics 2019 19:172

    Content type: Research article

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  38. Dementia with Lewy bodies (DLB) is still underdiagnosed or mistaken for other types of neurodegenerative diseases. Biomarkers such as 18-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) can be helpful.

    Authors: Astrid Melani Suantio, Hian Liang Huang, Cecilia Sze Nga Kwok, Darren Cheng Han Teo and Minh Ha Nguyen

    Citation: BMC Geriatrics 2019 19:150

    Content type: Case report

    Published on:

  39. Smartphone use has become an increasingly pervasive part of our daily lives, and as a portable media device, smartphones provide good support for cognitive training during aging. However, little is known about...

    Authors: Manqiong Yuan, Jia Chen, Zi Zhou, Jiahui Yin, Jielong Wu, Mingliang Luo, Lixia Wang and Ya Fang

    Citation: BMC Geriatrics 2019 19:140

    Content type: Research article

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  40. The main objective of this research was to evaluate the acceptance of technology based on a wearable lifelogging camera in a sample of older adults diagnosed with mild cognitive impairment (MCI).

    Authors: Olga Gelonch, Mireia Ribera, Núria Codern-Bové, Sílvia Ramos, Maria Quintana, Gloria Chico, Noemí Cerulla, Paula Lafarga, Petia Radeva and Maite Garolera

    Citation: BMC Geriatrics 2019 19:110

    Content type: Research article

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  41. Previous observational studies and clinical trials have shown that cholinesterase inhibitors (with or without memantine) provide benefit for patients with mild-to-moderate Alzheimer’s disease. However, the imp...

    Authors: Aina Soler, Guillem Amer, Alicia Leiva, Joana Ripoll, María Angeles Llorente, Alfonso Leiva, Joana Maria Taltavull, Rosa Molina and Joan Llobera

    Citation: BMC Geriatrics 2019 19:101

    Content type: Study protocol

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  42. The elderly, and especially those with an immuno-compromised status, are vulnerable to infectious diseases. The purpose of this study was to examine the clinical characteristics and therapeutic outcomes of cry...

    Authors: Wan-Chen Tsai, Chia-Yi Lien, Jun-Jun Lee, Wen-Chiu Hsiao, Chi-Ren Huang, Nai-Wen Tsai, Chiung-Chih Chang, Cheng-Hsien Lu and Wen-Neng Chang

    Citation: BMC Geriatrics 2019 19:91

    Content type: Research article

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  43. Older adults often suffer from age- and behavior-related brain changes affecting neuronal functioning and, therefore, cognitive and motor functions. The improvement of these functions might decrease falls and ...

    Authors: Alexandra Schättin, Corinne Baier, Domenique Mai, Verena Klamroth-Marganska, Isabelle Herter-Aeberli and Eling D. de Bruin

    Citation: BMC Geriatrics 2019 19:81

    Content type: Research article

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  44. Visual rating scales are still the most popular tools in assessing atrophy degrees of whole brain and lobes. However, the false negative rate of the previous cutoff score of visual rating scales was relatively...

    Authors: Mingqing Wei, Jing Shi, Jingnian Ni, Xuekai Zhang, Ting Li, Zilong Chen, Mengling Zhou, Liping Zhang, Zhongjian Tan, Yongyan Wang and Jinzhou Tian

    Citation: BMC Geriatrics 2019 19:59

    Content type: Research article

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  45. Stroke incidence has declined during the past decades. Yet, there is a concern that an ageing population together with improved survival after stroke will result in a raised proportion of the population who ha...

    Authors: Karin Modig, Mats Talbäck, Louise Ziegler and Anders Ahlbom

    Citation: BMC Geriatrics 2019 19:31

    Content type: Research article

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  46. Alterations in autonomic nervous system (ANS) activity might be involved in the pathophysiology of delirium. The aim was to explore autonomic cardiovascular control in older patients with and without delirium.

    Authors: Bjørn Erik Neerland, Torgeir Bruun Wyller and Vegard Bruun Bratholm Wyller

    Citation: BMC Geriatrics 2019 19:23

    Content type: Research article

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  47. Dementia patients often show neuropsychiatric symptoms, known as behavioral and psychological symptoms of dementia (BPSD). These are a common motive for medical consultations, hospitalizations, and nursing hom...

    Authors: Mireia Massot Mesquida, Montserrat Tristany Casas, Alicia Franzi Sisó, Isabel García Muñoz, Óscar Hernández Vian and Pere Torán Monserrat

    Citation: BMC Geriatrics 2019 19:7

    Content type: Research article

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  48. Aging and rural-urban disparities are two major social problems in today’s ever-developing China. Much of the existing literature has supported a negative association between adverse community setting with the...

    Authors: Yuanxi Xiang, Hossein Zare, Cuiling Guan and Darrell Gaskin

    Citation: BMC Geriatrics 2018 18:323

    Content type: Research article

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  49. The oldest-old (subjects aged 90 years and older) population represents the fastest growing segment of society and shows a high dementia prevalence rate of up to 40%. Only a few studies have investigated prote...

    Authors: Nienke Legdeur, Maryam Badissi, Stephen F. Carter, Sophie de Crom, Aleid van de Kreeke, Ralph Vreeswijk, Marijke C. Trappenburg, Mardien L. Oudega, Huiberdina L. Koek, Jos P. van Campen, Carolina J. P. W. Keijsers, Chinenye Amadi, Rainer Hinz, Mark F. Gordon, Gerald Novak, Jana Podhorna…

    Citation: BMC Geriatrics 2018 18:289

    Content type: Study protocol

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  50. Patients with delirium have increased risk of death, dementia and institutionalization, and prognosis differs between delirium motor subtypes. A few studies have identified associations between environmental f...

    Authors: Sigurd Evensen, Ingvild Saltvedt, Stian Lydersen, Torgeir Bruun Wyller, Kristin Taraldsen and Olav Sletvold

    Citation: BMC Geriatrics 2018 18:282

    Content type: Research article

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