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Neurology, stroke and cognition

This section considers manuscripts on all neurological topics. Including: Alzheimer’s, cognition, stroke, dementia, wandering behaviours.

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  1. Vertigo, dizziness and balance disorders (VDB) are among the most relevant contributors to the burden of disability among older adults living in the community and associated with immobility, limitations of act...

    Authors: Verena Regauer, Eva Seckler, Martin Müller and Petra Bauer

    Citation: BMC Geriatrics 2020 20:494

    Content type: Research article

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  2. Cognitive and functional measures are often measured and interpreted separately during the clinical evaluation of patients with cognitive impairment. This can sometimes lead to a challenging interpretation whe...

    Authors: Rocco Palumbo, Alberto Di Domenico, Federica Piras, Salvatore Bazzano, Mario Zerilli, Fabio Lorico and Erika Borella

    Citation: BMC Geriatrics 2020 20:492

    Content type: Research article

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  3. A dearth of differential research exists regarding the determinants of mild cognitive impairment (MCI) and moderate cognitive impairment or dementia among nursing home residents. This study aimed to identify a...

    Authors: Audai A. Hayajneh, Mohammad Rababa, Alia A. Alghwiri and Dina Masha’al

    Citation: BMC Geriatrics 2020 20:479

    Content type: Research article

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  4. Although many studies have reported numerous risk factors for postoperative delirium, data are scarce about preoperative anxiety as a risk factor. The study aimed to investigate the association between preoper...

    Authors: Koen Milisen, Bastiaan Van Grootven, Wim Hermans, Karen Mouton, Layth Al Tmimi, Steffen Rex and Elke Detroyer

    Citation: BMC Geriatrics 2020 20:478

    Content type: Research article

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  5. Cognitive decline is common in older adults. Similarly, the prevalence of renal dysfunction is also increased in the elderly population. We conducted this study to clarify the relationship between renal dysfun...

    Authors: Ji Yoon Kong, Jin Sug Kim, Min Hye Kang, Hyeon Seok Hwang, Chang Won Won and Kyung Hwan Jeong

    Citation: BMC Geriatrics 2020 20:462

    Content type: Research article

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  6. Biologic studies have suggested that tea may have neuroprotective activity. However, tea’s protective effect on cognitive function is controversial in human epidemiological studies, and no data, including the ...

    Authors: Jia Zhang, Anxin Wang, Xiaoli Zhang, Shuohua Chen, Shouling Wu, Xingquan Zhao and Qian Zhang

    Citation: BMC Geriatrics 2020 20:447

    Content type: Research article

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  7. Alzheimer’s disease (AD) is related to higher mortality but it is not entirely evident which causes of death explain this. The objective of this study was to assess the causes of death in a nationwide cohort o...

    Authors: Anna-Maija Tolppanen, Heidi Taipale, Marjaana Koponen, Jari Tiihonen and Sirpa Hartikainen

    Citation: BMC Geriatrics 2020 20:441

    Content type: Research article

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  8. Cognitive impairment is twice more frequent in elderly with type 2 diabetes mellitus (DM). This study was conducted to determine the association between glycemic control and cognitive performance among communi...

    Authors: Alberto J. Mimenza-Alvarado, Gilberto A. Jiménez-Castillo, Sara G. Yeverino-Castro, Abel J. Barragán-Berlanga, Mario U. Pérez-Zepeda, J. Alberto Ávila-Funes and Sara G. Aguilar-Navarro

    Citation: BMC Geriatrics 2020 20:424

    Content type: Research article

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  9. Recent data suggest that musical practice prevents age-related cognitive decline. But experimental evidence remains sparse and no concise information on the neurophysiological bases exists, although cognitive ...

    Authors: Clara E. James, Eckart Altenmüller, Matthias Kliegel, Tillmann H.C. Krüger, Dimitri Van De Ville, Florian Worschech, Laura Abdili, Daniel S. Scholz, Kristin Jünemann, Alexandra Hering, Frédéric Grouiller, Christopher Sinke and Damien Marie

    Citation: BMC Geriatrics 2020 20:418

    Content type: Study protocol

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  10. Hospitalizations carry considerable risks for frail, elderly patients; this is especially true for patients with dementia, who are more likely to experience delirium, falls, functional decline, iatrogenic comp...

    Authors: Karine Riad, Colleen Webber, Ricardo Batista, Michael Reaume, Emily Rhodes, Braden Knight, Denis Prud’homme and Peter Tanuseputro

    Citation: BMC Geriatrics 2020 20:397

    Content type: Research article

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  11. Chronic kidney disease (CKD), low serum albumin, and anemia are known risk factors for cognitive decline in older people. We investigated the association between kidney function and cognitive impairment severi...

    Authors: Jia-Jyun Wu, Shuo-Chun Weng, Chih-Kuang Liang, Chu-Sheng Lin, Tsuo-Hung Lan, Shih-Yi Lin and Yu-Te Lin

    Citation: BMC Geriatrics 2020 20:391

    Content type: Research article

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  12. Postoperative cognitive dysfunction is a common postoperative complication in elderly patients. In elderly patients, the decline of organ function and neuromuscular junction function make them more sensitive t...

    Authors: Bao Zhu, Defeng Sun, Lin Yang, Zhongliang Sun, Yan Feng and Chengcheng Deng

    Citation: BMC Geriatrics 2020 20:387

    Content type: Research article

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  13. Increasingly, older Chinese adults from rural areas are moving to urban areas to live with their children who have already migrated to these areas. However, few studies have examined this pattern of migration ...

    Authors: Jinzhao Xie, Jing Liao, Jing Zhang and Jing Gu

    Citation: BMC Geriatrics 2020 20:360

    Content type: Research article

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  14. Cognitive impairment and dementia following cerebrovascular disease are increasingly common in the UK. One potential strategy to prevent post-stroke cognitive decline is multimodal vascular risk factor managem...

    Authors: William J. Davison, Phyo K. Myint, Yoon K. Loke, Garth Ravenhill, David Turner, Chris Fox, Lee Shepstone and John F. Potter

    Citation: BMC Geriatrics 2020 20:353

    Content type: Research article

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  15. The association between amyloid deposition and cognitive, behavioral and physical performance in mild cognitive impairment (MCI) due to Alzheimer’s disease (AD) has been poorly investigated, especially in olde...

    Authors: Fulvio Lauretani, Livia Ruffini, Maura Scarlattei and Marcello Maggio

    Citation: BMC Geriatrics 2020 20:337

    Content type: Research article

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  16. Delirium is an extremely common hospital complication. No study to date has assessed whether a priori defined covariates; type of hospital setting and year of study publication, influence the relationship betw...

    Authors: May Zin Aung Thein, Jarett V. Pereira, Anita Nitchingham and Gideon A. Caplan

    Citation: BMC Geriatrics 2020 20:325

    Content type: Research article

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  17. South Korea is an aged society that continues to age rapidly. Therefore, the purpose of this study was to investigate the association between changes in lifestyle and cognitive functions in the South Korean el...

    Authors: Hyeon Ji Lee, Jieun Jang, Dong-Woo Choi, Wonjeong Chae, Eun-Cheol Park and Sung-In Jang

    Citation: BMC Geriatrics 2020 20:317

    Content type: Research article

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  18. The high burden of care associated with older stroke patients is a factor that threatens the health of family caregivers. Identifying the needs of family caregivers in this group of patients can help provide e...

    Authors: Mansoureh Ashghali Farahani, Shiva Bahloli, Roohangiz JamshidiOrak and Fatemeh Ghaffari

    Citation: BMC Geriatrics 2020 20:313

    Content type: Research article

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  19. Many people with dementia live in care homes, where staff can struggle to meet their complex needs. Successful practice improvement interventions in these settings require strong managerial support, but little...

    Authors: R. Kelley, A. W. Griffiths, E. Shoesmith, J. McDermid, E. Couch, O. Robinson, D. Perfect and C. A. Surr

    Citation: BMC Geriatrics 2020 20:303

    Content type: Research article

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  20. Statins have been recommended by several guidelines as the primary prevention medication for cardiovascular diseases. However, the benefits of statin therapy for cerebral small vessel disease (CSVD), particula...

    Authors: Yuqi Guo, Yunpeng Li, Xukui Liu, Yi Cui, Yingxin Zhao, Shangwen Sun, Qing Jia, Qiang Chai, Gary Gong, Hua Zhang and Zhendong Liu

    Citation: BMC Geriatrics 2020 20:292

    Content type: Research article

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  21. This study aimed to evaluate the relationship between the history of late-life falling and the development of Parkinson’s disease (PD) and investigate whether depressive symptoms interact with falling to incre...

    Authors: Yu Jin Jung, Ryul Kim, Dallah Yoo, Kyungdo Han and Jee-Young Lee

    Citation: BMC Geriatrics 2020 20:284

    Content type: Research article

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  22. Patients with mild cognitive impairment (MCI) experience alterations of functional parameters, such as an impaired balance or gait. The current systematic review set out to investigate whether functional objec...

    Authors: Iván José Fuentes-Abolafio, Brendon Stubbs, Luis Miguel Pérez-Belmonte, María Rosa Bernal-López, Ricardo Gómez-Huelgas and Antonio Cuesta-Vargas

    Citation: BMC Geriatrics 2020 20:282

    Content type: Research article

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  23. Discrimination between early-stage dementia and other cognitive impairment diagnoses is central to enable appropriate interventions. Previous studies indicate that dual-task testing may be useful in such diffe...

    Authors: Hanna B. Åhman, Ylva Cedervall, Lena Kilander, Vilmantas Giedraitis, Lars Berglund, Kevin J. McKee, Erik Rosendahl, Martin Ingelsson and Anna Cristina Åberg

    Citation: BMC Geriatrics 2020 20:258

    Content type: Research article

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  24. Dementia is an increasing public health threat worldwide. The pathogenesis of dementia has not been fully elucidated yet. Inflammatory processes are hypothesized to play an important role as a driver for cogni...

    Authors: Vanessa Stadlbauer, Lara Engertsberger, Irina Komarova, Nicole Feldbacher, Bettina Leber, Gerald Pichler, Nicole Fink, Monika Scarpatetti, Walter Schippinger, Reinhold Schmidt and Angela Horvath

    Citation: BMC Geriatrics 2020 20:248

    Content type: Research article

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  25. Use of companion robots may reduce older people’s depression, loneliness and agitation. This benefit has to be contrasted against possible ethical concerns raised by philosophers in the field around issues suc...

    Authors: Hannah L. Bradwell, Rhona Winnington, Serge Thill and Ray B. Jones

    Citation: BMC Geriatrics 2020 20:244

    Content type: Research article

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  26. Physical and social environments may influence cognition health in older adults. However, evidence regarding physical and social environments linked to dementia is lacking, especially in Asia. This study aims ...

    Authors: Chih-Ching Liu, Yu Sun, Shiann-Far Kung, Hsien-Wen Kuo, Nuan-Ching Huang, Chung-Yi Li and Susan C. Hu

    Citation: BMC Geriatrics 2020 20:226

    Content type: Research article

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  27. Hematologic malignancies can spread to the central nervous system (CNS), either as focal lesions or as leptomeningeal disease. Marginal zone lymphoma (MZL) is a low-grade non-Hodgkin lymphoma and generally pre...

    Authors: Lisa Dreessen, Nicolas Maréchal, Michel Verheyden, Ann De Becker, Kristin Jochmans, Tim Vanderhasselt, Bert Bravenboer and Ingo Beyer

    Citation: BMC Geriatrics 2020 20:213

    Content type: Case report

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  28. Ocular imaging receives much attention as a source of potential biomarkers for dementia. In the present study, we analyze these ocular biomarkers in cognitively impaired and healthy participants in a populatio...

    Authors: Jacoba A. van de Kreeke, Nienke Legdeur, Maryam Badissi, H. Ton Nguyen, Elles Konijnenberg, Jori Tomassen, Mara ten Kate, Anouk den Braber, Andrea B. Maier, H. Stevie Tan, Frank D. Verbraak and Pieter Jelle Visser

    Citation: BMC Geriatrics 2020 20:155

    Content type: Research article

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  29. This study explored the effects of physical activity and sedentary behaviour on the decline of cognitive ability among the elderly. To compensate for the limitations of self-reported physical activity, objecti...

    Authors: Zhi-jian Wu, Zhu-ying Wang, Bing-qian Hu, Xu-hui Zhang, Fan Zhang, Hou-lei Wang and Fang-hui Li

    Citation: BMC Geriatrics 2020 20:149

    Content type: Research article

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  30. The relationship between frailty and dementia is unclear and there are very few population-based studies regarding this issue in China. The purpose of this study is to estimate the association between frailty ...

    Authors: Minghui Li, Yueqin Huang, Zhaorui Liu, Rui Shen, Hongguang Chen, Chao Ma, Tingting Zhang, Shuran Li and Martin Prince

    Citation: BMC Geriatrics 2020 20:138

    Content type: Research article

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  31. Physical activity may decrease the risk of dementia; however, previous cohort studies seldom investigated the different types of physical activity and household activities. Our objective was to analyze the lin...

    Authors: Caroline Dupré, Bienvenu Bongue, Catherine Helmer, Jean François Dartigues, David Hupin, Frédéric Roche, Claudine Berr and Isabelle Carrière

    Citation: BMC Geriatrics 2020 20:132

    Content type: Research article

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  32. The implementation of evidence-based interventions for people with dementia is complex and challenging. However, successful implementation might be a key element to ensure evidence-based practice and high qual...

    Authors: Melanie Karrer, Julian Hirt, Adelheid Zeller and Susi Saxer

    Citation: BMC Geriatrics 2020 20:127

    Content type: Research article

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  33. Motoric cognitive risk syndrome (MCR) is a newly proposed predementia syndrome incorporating subjective cognitive complaints and slow gait. Previous studies have reported that subjective cognitive complaints a...

    Authors: Shanshan Shen, Xingkun Zeng, Liyu Xu, Lingyan Chen, Zixia Liu, Jiaojiao Chu, Yinghong Yang, Xiushao Wu and Xujiao Chen

    Citation: BMC Geriatrics 2020 20:110

    Content type: Research article

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  34. Antimuscarinics are often used for treatment of overactive bladder (OAB), but exposure to medications such as antimuscarinics that have anticholinergic properties has been linked to adverse cognitive effects. ...

    Authors: Tomas L. Griebling, Noll L. Campbell, Jeffrey Mangel, David Staskin, Sender Herschorn, Dina Elsouda and Carol R. Schermer

    Citation: BMC Geriatrics 2020 20:109

    Content type: Research article

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  35. Research in the area of public stigma and Alzheimer’s disease (AD) is limited to examining stigmatic beliefs towards persons aged 65 and over (i.e., persons with late-onset dementia). The aim of the present st...

    Authors: Perla Werner, Lilach Raviv-Turgeman and Patrick W. Corrigan

    Citation: BMC Geriatrics 2020 20:104

    Content type: Research article

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  36. There remains a lack of large-scale clinical studies of cognitive impairment that aim to increase diagnostic and prognostic accuracy as well as validate previous research findings. The MemClin project will ama...

    Authors: Urban Ekman, Daniel Ferreira, J-Sebastian Muehlboeck, John Wallert, Anna Rennie, Maria Eriksdotter, Lars-Olof Wahlund and Eric Westman

    Citation: BMC Geriatrics 2020 20:93

    Content type: Research article

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  37. The ability to walk and perform cognitive tasks simultaneously is a key aspect of daily life. Performance declines in these dual-tasks may be associated with early signs of neurodegenerative disease and increa...

    Authors: David A. Raichlen, Pradyumna K. Bharadwaj, Lauren A. Nguyen, Mary Kathryn Franchetti, Erika K. Zigman, Abigail R. Solorio and Gene E. Alexander

    Citation: BMC Geriatrics 2020 20:83

    Content type: Research article

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  38. People with dementia often require full-time caregivers especially in the later stages of their condition. People with dementia and caregivers’ access to reliable information on dementia is essential as it may...

    Authors: Aijia Soong, Shu Ting Au, Bhone Myint Kyaw, Yin Leng Theng and Lorainne Tudor Car

    Citation: BMC Geriatrics 2020 20:61

    Content type: Research article

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  39. All individuals with severe dementia should be offered careful hand feeding. However, under certain circumstances, people with severe dementia have a feeding tube placed. In Taiwan, tube feeding rate in dement...

    Authors: Hsiao-Hui Chou, Meng-Ting Tsou and Lee-Ching Hwang

    Citation: BMC Geriatrics 2020 20:60

    Content type: Research article

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  40. There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s...

    Authors: Vincent Mubangizi, Samuel Maling, Celestino Obua and Alexander C. Tsai

    Citation: BMC Geriatrics 2020 20:48

    Content type: Research article

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  41. With the fast-paced aging and increasing digitalization of society, there has been a growing interest in the effect of mobile device use on cognitive function and depression in older adults. However, research ...

    Authors: Lu Lin, Xiu-Chen Jing, Shu-Jiao Lv, Jing-Hong Liang, Li Tian, Hui-Ling Li, Martine Puts and Yong Xu

    Citation: BMC Geriatrics 2020 20:41

    Content type: Research article

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  42. To identify the incidence of, risk factors for, and outcomes associated with postoperative delirium (POD) in older adult patients who underwent noncardiac surgery.

    Authors: Arissara Iamaroon, Titima Wongviriyawong, Patumporn Sura-arunsumrit, Nattikan Wiwatnodom, Nichakarn Rewuri and Onuma Chaiwat

    Citation: BMC Geriatrics 2020 20:40

    Content type: Research article

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  43. Cognition has been related with gait speed in older adults; however, studies involving the oldest age group, where many have mobility disability and cognitive impairment, are few. The aim was to investigate th...

    Authors: Jerry Öhlin, Anders Ahlgren, Robert Folkesson, Yngve Gustafson, Håkan Littbrand, Birgitta Olofsson and Annika Toots

    Citation: BMC Geriatrics 2020 20:34

    Content type: Research article

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  44. Cognitive impairment is a major contributor to mortality among the elderly. However, the relationship between cognitive impairment evaluated by educational levels and mortality and the trend between cognitive ...

    Authors: Jun Duan, Yue-Bin Lv, Xiang Gao, Jin-Hui Zhou, Virginia Byers Kraus, Yi Zeng, Hong Su and Xiao-Ming Shi

    Citation: BMC Geriatrics 2020 20:29

    Content type: Research article

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  45. Stroke is a highly prevalent disease among older people and can have a major impact on daily functioning and quality of life. When community-dwelling older people are hospitalized due to stroke, discharge to a...

    Authors: Tom P. M. M. Vluggen, Jolanda C. M. van Haastregt, Frans E. S. Tan, Gertrudis I. J. M. Kempen, Jos M. G. A. Schols and Jeanine A. Verbunt

    Citation: BMC Geriatrics 2020 20:25

    Content type: Research article

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  46. Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focuse...

    Authors: Werayuth Srithumsuk, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Yuya Akagi, Nonglak Klinpudtan, Eri Kiyoshige, Kayo Godai, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Madoka Ogawa, Hiroki Inagaki…

    Citation: BMC Geriatrics 2020 20:24

    Content type: Research article

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