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Neurology, stroke and cognition

This section considers manuscripts on all neurological topics. Including: Alzheimer’s, cognition, stroke, dementia, wandering behaviours.

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  1. This study investigated the differences in caregiver activity, caregiver burden, and awareness of both caregivers and patients with Alzheimer’s disease (AD) across different Asian locations.

    Authors: Yong S. Shim, Kee Hyung Park, Christopher Chen, Jacqueline C. Dominguez, Kyunghun Kang, Hee-Jin Kim, Zhen Hong, Yu-Te Lin, Leung-Wing Chu, San Jung and SangYun Kim

    Citation: BMC Geriatrics 2021 21:230

    Content type: Research article

    Published on:

  2. People with Parkinson’s disease (PD) have described their walking difficulties as linked to activity avoidance, social isolation, reduced independence and quality of life. There is a knowledge gap regarding pr...

    Authors: Magnus Lindh-Rengifo, Stina B. Jonasson, Susann Ullén, Niklas Mattsson-Carlgren and Maria H. Nilsson

    Citation: BMC Geriatrics 2021 21:221

    Content type: Research article

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  3. Delirium is a common disorder among hospitalized older patients and results in increased morbidity and mortality. The prevention of delirium is still challenging in older patient care. The role of antipsychoti...

    Authors: Saran Thanapluetiwong, Sirasa Ruangritchankul, Orapitchaya Sriwannopas, Sirintorn Chansirikarnjana, Pichai Ittasakul, Tipanetr Ngamkala, Lalita Sukumalin, Piangporn Charernwat, Krittika Saranburut and Taweevat Assavapokee

    Citation: BMC Geriatrics 2021 21:215

    Content type: Research article

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  4. Transcatheter aortic valve replacement is increasingly performed in frail older patients who were previously ineligible for a standard surgical procedure. The objectives of this study are to determine delirium...

    Authors: Marc Humbert, Christophe J. Büla, Olivier Muller, Hélène Krief and Pierre Monney

    Citation: BMC Geriatrics 2021 21:153

    Content type: Research article

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  5. Almost half of the stroke patients admitted to geriatric rehabilitation has persisting problems after discharge. Currently, there is no evidence based geriatric rehabilitation programme available for older str...

    Authors: Tom P. M. M. Vluggen, Jolanda C. M. van Haastregt, Frans E. Tan, Jeanine A. Verbunt, Caroline M. van Heugten and Jos M. G. A. Schols

    Citation: BMC Geriatrics 2021 21:134

    Content type: Research article

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  6. With age, most cognitive functions decline. As the number of people aged 60 years and older is expected to rise rapidly within the next decades, identifying interventions that promote healthy cognitive ageing ...

    Authors: Judith Alina Grossmann, Verena Magdalena Koelsch, Merve Gul Degirmenci, Steffen Aschenbrenner, Birgit Teichmann and Patric Meyer

    Citation: BMC Geriatrics 2021 21:122

    Content type: Study protocol

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  7. Demographic aging is a generalised event and the proportion of older adults is increasing rapidly worldwide with chronic pathologies, disability, and complexity of health needs. The intracerebral haemorrhage (...

    Authors: Blanca Lorman-Carbó, Josep Lluís Clua-Espuny, Eulàlia Muria-Subirats, Juan Ballesta-Ors, Maria Antònia González-Henares, José Fernández-Sáez and Francisco M. Martín-Luján

    Citation: BMC Geriatrics 2021 21:106

    Content type: Research article

    Published on:

  8. Process evaluations provide contextual insight into the way in which interventions are delivered. This information is essential when designing strategies to implement programs into wider clinical practice. We ...

    Authors: Breiffni Leavy, Conran Joseph, Lydia Kwak and Erika Franzén

    Citation: BMC Geriatrics 2021 21:96

    Content type: Research article

    Published on:

  9. Physical aging increases the sensitivity to the effects of substance use, elevating the risk for cognitive impairment among older adults. Since studies on the association of substance use with cognitive abilit...

    Authors: T. Muhammad, Manideep Govindu and Shobhit Srivastava

    Citation: BMC Geriatrics 2021 21:85

    Content type: Research article

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  10. Everyday cognition is the application of basic cognitive skills and knowledge of the specific cognitive domain for the resolution of problems that are integrated within the instrumental domains of functioning....

    Authors: Celia Sánchez Gómez and Eduardo José Fernández Rodríguez

    Citation: BMC Geriatrics 2021 21:79

    Content type: Research article

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  11. Previous studies have reported associations between hearing impairment (HI) and cognitive impairment, but the evidence is not conclusive while considering concurrent geriatric syndromes. Especially, evidence f...

    Authors: Chi-Jung Tai, Tzyy-Guey Tseng, Yu-Han Hsiao, Tsu-Ann Kuo, Ching-Ya Huang, Yi-Hsin Yang and Meng-Chih Lee

    Citation: BMC Geriatrics 2021 21:76

    Content type: Research article

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  14. In recent decades, previous studies have noted the importance of frailty, which is a frequently used term in perioperative risk evaluations. Psychological and socioeconomical domains were investigated as part ...

    Authors: András Szabó, Krisztina Tóth, Ádám Nagy, Dominika Domokos, Nikoletta Czobor, Csaba Eke, Ágnes Sándor, Béla Merkely, Éva Susánszky, János Gál and Andrea Székely

    Citation: BMC Geriatrics 2021 21:46

    Content type: Research article

    Published on:

  15. The key part of home care services is the assessment of the needs of the home environment for older adults with dementia. The present study was conducted to evaluate the psychometric properties of a newly adap...

    Authors: Lai You Li, Ning Sun, Li Bo Yu, Xiao Xin Dong, Yu Chen Ying, Han Jun Lang and Li Heng Zhou

    Citation: BMC Geriatrics 2021 21:28

    Content type: Research article

    Published on:

  16. The Montessori Method underpinned by the principle of person-centered care has been widely adopted to design activities for people with dementia. However, the methodological quality of the existing evidence is...

    Authors: Helen Yue-lai Chan, Yee-man Yau, Si-fan. Li, Ka-shi Kwong, Yuen-yu Chong, Iris Fung-kam Lee and Doris Sau-fung Yu

    Citation: BMC Geriatrics 2021 21:24

    Content type: Research article

    Published on:

  17. Mild cognitive impairment (MCI) is an intermediate phase between normal cognitive ageing and overt dementia, with amnesic MCI (aMCI) being the dominant subtype. This study aims to synthesise the prevalence res...

    Authors: Yuan Lu, Chaojie Liu, Dehua Yu, Sally Fawkes, Jia Ma, Min Zhang and Chunbo Li

    Citation: BMC Geriatrics 2021 21:10

    Content type: Research article

    Published on:

  18. The outbreak of the Corona virus is a challenge for health care systems worldwide. The aim of this study is to analyze a) knowledge about, and feelings related to the Corona-pandemic. Describe b) loneliness, d...

    Authors: Jochen René Thyrian, Friederike Kracht, Angela Nikelski, Melanie Boekholt, Fanny Schumacher-Schönert, Anika Rädke, Bernhard Michalowsky, Horst Christian Vollmar, Wolfgang Hoffmann, Francisca S. Rodriguez and Stefan H. Kreisel

    Citation: BMC Geriatrics 2020 20:540

    Content type: Research article

    Published on:

  19. Delirium is associated with high mortality after cardiac surgery. However, evidence on the epidemiology of delirium in patients with acute decompensated heart failure (ADHF) is limited. This study aimed to ass...

    Authors: Misun Pak, Masahiko Hara, Shoko Miura, Motohide Furuya, Masatake Tamaki, Taiji Okada, Nobuhide Watanabe, Akihiro Endo and Kazuaki Tanabe

    Citation: BMC Geriatrics 2020 20:524

    Content type: Research article

    Published on:

  20. This systematic review aimed to explore the process of decision-making for nutrition and hydration for people living with dementia from the perspectives and experiences of all involved.

    Authors: Kanthee Anantapong, Nathan Davies, Justin Chan, Daisy McInnerney and Elizabeth L. Sampson

    Citation: BMC Geriatrics 2020 20:520

    Content type: Research article

    Published on:

  22. Several factors may play a role in the ability of patients with Alzheimer’s disease to perform activities of daily living (ADL). The aim of this study was to examine the impact of different aspects of physical...

    Authors: Frederikke K Clemmensen, Kristine Hoffmann, Volkert Siersma, Nanna Sobol, Nina Beyer, Birgitte B Andersen, Asmus Vogel, Annette Lolk, Hanne Gottrup, Peter Høgh, Gunhild Waldemar, Steen G Hasselbalch and Kristian S Frederiksen

    Citation: BMC Geriatrics 2020 20:513

    Content type: Research article

    Published on:

  23. Frailty and cognitive decline are highly prevalent among older adults. However, the relationship between frailty and mild behavioral impairment (MBI), a dementia risk syndrome characterized by later-life emerg...

    Authors: Shaoyi Fan, Ximin Liang, Tianchan Yun, Zhong Pei, Bin Hu, Zahinoor Ismail, Zhimin Yang and Fuping Xu

    Citation: BMC Geriatrics 2020 20:510

    Content type: Research article

    Published on:

  24. With the global population aging and life expectancy increasing, dementia has turned a priority in the health care system. In Chile, dementia is one of the most important causes of disability in the elderly an...

    Authors: Andrea Slachevsky, Pedro Zitko, David Martínez-Pernía, Gonzalo Forno, Felipe A. Court, Patricia Lillo, Roque Villagra, Claudia Duran-Aniotz, Teresa Parrao, Rodrigo Assar, Paulina Orellana, Carolina Toledo, Rodrigo Rivera, Agustín Ibañez, Mario A. Parra, Christian González-Billault…

    Citation: BMC Geriatrics 2020 20:505

    Content type: Study protocol

    Published on:

  25. Vertigo, dizziness and balance disorders (VDB) are among the most relevant contributors to the burden of disability among older adults living in the community and associated with immobility, limitations of act...

    Authors: Verena Regauer, Eva Seckler, Martin Müller and Petra Bauer

    Citation: BMC Geriatrics 2020 20:494

    Content type: Research article

    Published on:

  26. Cognitive and functional measures are often measured and interpreted separately during the clinical evaluation of patients with cognitive impairment. This can sometimes lead to a challenging interpretation whe...

    Authors: Rocco Palumbo, Alberto Di Domenico, Federica Piras, Salvatore Bazzano, Mario Zerilli, Fabio Lorico and Erika Borella

    Citation: BMC Geriatrics 2020 20:492

    Content type: Research article

    Published on:

  27. A dearth of differential research exists regarding the determinants of mild cognitive impairment (MCI) and moderate cognitive impairment or dementia among nursing home residents. This study aimed to identify a...

    Authors: Audai A. Hayajneh, Mohammad Rababa, Alia A. Alghwiri and Dina Masha’al

    Citation: BMC Geriatrics 2020 20:479

    Content type: Research article

    Published on:

  28. Although many studies have reported numerous risk factors for postoperative delirium, data are scarce about preoperative anxiety as a risk factor. The study aimed to investigate the association between preoper...

    Authors: Koen Milisen, Bastiaan Van Grootven, Wim Hermans, Karen Mouton, Layth Al Tmimi, Steffen Rex and Elke Detroyer

    Citation: BMC Geriatrics 2020 20:478

    Content type: Research article

    Published on:

  29. Cognitive decline is common in older adults. Similarly, the prevalence of renal dysfunction is also increased in the elderly population. We conducted this study to clarify the relationship between renal dysfun...

    Authors: Ji Yoon Kong, Jin Sug Kim, Min Hye Kang, Hyeon Seok Hwang, Chang Won Won and Kyung Hwan Jeong

    Citation: BMC Geriatrics 2020 20:462

    Content type: Research article

    Published on:

  30. Biologic studies have suggested that tea may have neuroprotective activity. However, tea’s protective effect on cognitive function is controversial in human epidemiological studies, and no data, including the ...

    Authors: Jia Zhang, Anxin Wang, Xiaoli Zhang, Shuohua Chen, Shouling Wu, Xingquan Zhao and Qian Zhang

    Citation: BMC Geriatrics 2020 20:447

    Content type: Research article

    Published on:

  31. Alzheimer’s disease (AD) is related to higher mortality but it is not entirely evident which causes of death explain this. The objective of this study was to assess the causes of death in a nationwide cohort o...

    Authors: Anna-Maija Tolppanen, Heidi Taipale, Marjaana Koponen, Jari Tiihonen and Sirpa Hartikainen

    Citation: BMC Geriatrics 2020 20:441

    Content type: Research article

    Published on:

  32. Cognitive impairment is twice more frequent in elderly with type 2 diabetes mellitus (DM). This study was conducted to determine the association between glycemic control and cognitive performance among communi...

    Authors: Alberto J. Mimenza-Alvarado, Gilberto A. Jiménez-Castillo, Sara G. Yeverino-Castro, Abel J. Barragán-Berlanga, Mario U. Pérez-Zepeda, J. Alberto Ávila-Funes and Sara G. Aguilar-Navarro

    Citation: BMC Geriatrics 2020 20:424

    Content type: Research article

    Published on:

  33. Recent data suggest that musical practice prevents age-related cognitive decline. But experimental evidence remains sparse and no concise information on the neurophysiological bases exists, although cognitive ...

    Authors: Clara E. James, Eckart Altenmüller, Matthias Kliegel, Tillmann H.C. Krüger, Dimitri Van De Ville, Florian Worschech, Laura Abdili, Daniel S. Scholz, Kristin Jünemann, Alexandra Hering, Frédéric Grouiller, Christopher Sinke and Damien Marie

    Citation: BMC Geriatrics 2020 20:418

    Content type: Study protocol

    Published on:

  34. Hospitalizations carry considerable risks for frail, elderly patients; this is especially true for patients with dementia, who are more likely to experience delirium, falls, functional decline, iatrogenic comp...

    Authors: Karine Riad, Colleen Webber, Ricardo Batista, Michael Reaume, Emily Rhodes, Braden Knight, Denis Prud’homme and Peter Tanuseputro

    Citation: BMC Geriatrics 2020 20:397

    Content type: Research article

    Published on:

  36. Chronic kidney disease (CKD), low serum albumin, and anemia are known risk factors for cognitive decline in older people. We investigated the association between kidney function and cognitive impairment severi...

    Authors: Jia-Jyun Wu, Shuo-Chun Weng, Chih-Kuang Liang, Chu-Sheng Lin, Tsuo-Hung Lan, Shih-Yi Lin and Yu-Te Lin

    Citation: BMC Geriatrics 2020 20:391

    Content type: Research article

    Published on:

  37. Postoperative cognitive dysfunction is a common postoperative complication in elderly patients. In elderly patients, the decline of organ function and neuromuscular junction function make them more sensitive t...

    Authors: Bao Zhu, Defeng Sun, Lin Yang, Zhongliang Sun, Yan Feng and Chengcheng Deng

    Citation: BMC Geriatrics 2020 20:387

    Content type: Research article

    Published on:

  38. Increasingly, older Chinese adults from rural areas are moving to urban areas to live with their children who have already migrated to these areas. However, few studies have examined this pattern of migration ...

    Authors: Jinzhao Xie, Jing Liao, Jing Zhang and Jing Gu

    Citation: BMC Geriatrics 2020 20:360

    Content type: Research article

    Published on:

  39. Cognitive impairment and dementia following cerebrovascular disease are increasingly common in the UK. One potential strategy to prevent post-stroke cognitive decline is multimodal vascular risk factor managem...

    Authors: William J. Davison, Phyo K. Myint, Yoon K. Loke, Garth Ravenhill, David Turner, Chris Fox, Lee Shepstone and John F. Potter

    Citation: BMC Geriatrics 2020 20:353

    Content type: Research article

    Published on:

  40. The association between amyloid deposition and cognitive, behavioral and physical performance in mild cognitive impairment (MCI) due to Alzheimer’s disease (AD) has been poorly investigated, especially in olde...

    Authors: Fulvio Lauretani, Livia Ruffini, Maura Scarlattei and Marcello Maggio

    Citation: BMC Geriatrics 2020 20:337

    Content type: Research article

    Published on:

  41. Delirium is an extremely common hospital complication. No study to date has assessed whether a priori defined covariates; type of hospital setting and year of study publication, influence the relationship betw...

    Authors: May Zin Aung Thein, Jarett V. Pereira, Anita Nitchingham and Gideon A. Caplan

    Citation: BMC Geriatrics 2020 20:325

    Content type: Research article

    Published on:

  42. South Korea is an aged society that continues to age rapidly. Therefore, the purpose of this study was to investigate the association between changes in lifestyle and cognitive functions in the South Korean el...

    Authors: Hyeon Ji Lee, Jieun Jang, Dong-Woo Choi, Wonjeong Chae, Eun-Cheol Park and Sung-In Jang

    Citation: BMC Geriatrics 2020 20:317

    Content type: Research article

    Published on:

  43. The high burden of care associated with older stroke patients is a factor that threatens the health of family caregivers. Identifying the needs of family caregivers in this group of patients can help provide e...

    Authors: Mansoureh Ashghali Farahani, Shiva Bahloli, Roohangiz JamshidiOrak and Fatemeh Ghaffari

    Citation: BMC Geriatrics 2020 20:313

    Content type: Research article

    Published on:

  44. Many people with dementia live in care homes, where staff can struggle to meet their complex needs. Successful practice improvement interventions in these settings require strong managerial support, but little...

    Authors: R. Kelley, A. W. Griffiths, E. Shoesmith, J. McDermid, E. Couch, O. Robinson, D. Perfect and C. A. Surr

    Citation: BMC Geriatrics 2020 20:303

    Content type: Research article

    Published on:

  45. Statins have been recommended by several guidelines as the primary prevention medication for cardiovascular diseases. However, the benefits of statin therapy for cerebral small vessel disease (CSVD), particula...

    Authors: Yuqi Guo, Yunpeng Li, Xukui Liu, Yi Cui, Yingxin Zhao, Shangwen Sun, Qing Jia, Qiang Chai, Gary Gong, Hua Zhang and Zhendong Liu

    Citation: BMC Geriatrics 2020 20:292

    Content type: Research article

    Published on:

  46. This study aimed to evaluate the relationship between the history of late-life falling and the development of Parkinson’s disease (PD) and investigate whether depressive symptoms interact with falling to incre...

    Authors: Yu Jin Jung, Ryul Kim, Dallah Yoo, Kyungdo Han and Jee-Young Lee

    Citation: BMC Geriatrics 2020 20:284

    Content type: Research article

    Published on:

  47. Patients with mild cognitive impairment (MCI) experience alterations of functional parameters, such as an impaired balance or gait. The current systematic review set out to investigate whether functional objec...

    Authors: Iván José Fuentes-Abolafio, Brendon Stubbs, Luis Miguel Pérez-Belmonte, María Rosa Bernal-López, Ricardo Gómez-Huelgas and Antonio Cuesta-Vargas

    Citation: BMC Geriatrics 2020 20:282

    Content type: Research article

    Published on:

  49. Discrimination between early-stage dementia and other cognitive impairment diagnoses is central to enable appropriate interventions. Previous studies indicate that dual-task testing may be useful in such diffe...

    Authors: Hanna B. Åhman, Ylva Cedervall, Lena Kilander, Vilmantas Giedraitis, Lars Berglund, Kevin J. McKee, Erik Rosendahl, Martin Ingelsson and Anna Cristina Åberg

    Citation: BMC Geriatrics 2020 20:258

    Content type: Research article

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  50. Dementia is an increasing public health threat worldwide. The pathogenesis of dementia has not been fully elucidated yet. Inflammatory processes are hypothesized to play an important role as a driver for cogni...

    Authors: Vanessa Stadlbauer, Lara Engertsberger, Irina Komarova, Nicole Feldbacher, Bettina Leber, Gerald Pichler, Nicole Fink, Monika Scarpatetti, Walter Schippinger, Reinhold Schmidt and Angela Horvath

    Citation: BMC Geriatrics 2020 20:248

    Content type: Research article

    Published on:

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