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Neurology, stroke and cognition

Section edited by Pieter Jelle Visser

This section considers manuscripts on all neurological topics. Including: Alzheimer’s, cognition, stroke, dementia, wandering behaviours.

Page 1 of 3

  1. Studies have shown an association between lower urinary tract symptoms (LUTS) and an increased risk of dementia. Whether anticholinergic use contributes to the development of dementia in patients with LUTS rem...

    Authors: Yi-Chi Wang, Yung-Liang Chen, Chun-Che Huang, Chung-Han Ho, Yu-Tung Huang, Ming-Ping Wu, Ming-Jung Ou, Chiu-Hsien Yang and Ping-Jen Chen

    Citation: BMC Geriatrics 2019 19:380

    Content type: Research article

    Published on:

  2. Stroke patients have increased risks of falls. We examined national registry data to evaluate the association between post-stroke functional level and the risk of low falls among post-stroke patients.

    Authors: Wycliffe E. Wei, Deirdre A. De Silva, Hui Meng Chang, Jiali Yao, David B. Matchar, Sherry H. Y. Young, Siew Ju See, Gek Hsiang Lim, Ting Hway Wong and Narayanaswamy Venketasubramanian

    Citation: BMC Geriatrics 2019 19:373

    Content type: Research article

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  3. We investigated the association between trajectories of verbal episodic memory and burden of cardiovascular risk factors in middle-aged and older community-dwellers.

    Authors: Beatriz Olaya, Maria Victoria Moneta, Martin Bobak, Josep Maria Haro and Panayotes Demakakos

    Citation: BMC Geriatrics 2019 19:337

    Content type: Research article

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  4. C677T point mutation in methylenetetrahydrofolate reductase (MTHFR) gene have been found to be associated with ischemic stroke in general population, while the results seem inconsistent. We aim to assess the a...

    Authors: Guilin Chang, Zheng Kuai, Jia Wang, Jiayu Wu, Kan Xu, Ying Yuan and Yu Hu

    Citation: BMC Geriatrics 2019 19:331

    Content type: Research article

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  5. Our objective was to characterize the relationship of anemia and hemoglobin concentrations with cross-sectional cognitive functions and changes in cognitive functions over 2 years in a large sample of Chinese ...

    Authors: Tingting Qin, Mingming Yan, Zhen Fu, Yating Song, Wanrong Lu, A’dan Fu and Ping Yin

    Citation: BMC Geriatrics 2019 19:305

    Content type: Research article

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  6. People with dementia describe experiences of loss that threaten their autonomy and ability to contribute to society. They often have difficulties with orientation, loss of roll function, and fear about the fut...

    Authors: Guro Hanevold Bjørkløf, Anne-Sofie Helvik, Tanja Louise Ibsen, Elisabeth Wiken Telenius, Ellen Karine Grov and Siren Eriksen

    Citation: BMC Geriatrics 2019 19:295

    Content type: Research article

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  7. The prevention of pneumonia is critical for patients with acute ischaemic stroke (AIS). The six subscales in the Braden Scale seem to be related to the occurrence of pneumonia. We aimed to evaluate the feasibi...

    Authors: Yunlong Ding, Yazhou Yan, Jiali Niu, Yanrong Zhang, Zhiqun Gu, Ping Tang and Yan Liu

    Citation: BMC Geriatrics 2019 19:259

    Content type: Research article

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  8. Impaired cognition is a major risk factor for perioperative delirium. It is essential to provide good pain control in patients with hip fractures and especially important in patients with severely impaired cog...

    Authors: Pär Wennberg, Margareta Möller, Johan Herlitz and Elisabeth Kenne Sarenmalm

    Citation: BMC Geriatrics 2019 19:252

    Content type: Research article

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  10. Internationally, there is a drive to involve patients and the public in health research, due to recognition that patient and public involvement (PPI) may increase the impact and relevance of health research. T...

    Authors: Jahanara Miah, Piers Dawes, Steven Edwards, Iracema Leroi, Bella Starling and Suzanne Parsons

    Citation: BMC Geriatrics 2019 19:220

    Content type: Research article

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  11. In the absence of treatment options, the WHO emphasizes the identification of effective prevention strategies as a key element to counteract the dementia epidemic. Regarding the complex nature of dementia, tri...

    Authors: Andrea Zülke, Tobias Luck, Alexander Pabst, Wolfgang Hoffmann, Jochen René Thyrian, Jochen Gensichen, Hanna Kaduszkiewicz, Hans-Helmut König, Walter E. Haefeli, David Czock, Birgitt Wiese, Thomas Frese, Susanne Röhr and Steffi G. Riedel-Heller

    Citation: BMC Geriatrics 2019 19:203

    Content type: Study protocol

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  12. The identification of factors associated with functional impairment, in particular those which are potentially modifiable, may help to delay the advanced stages of functional dependence in patients with neuroc...

    Authors: Virginie Dauphinot, Claire Moutet, Isabelle Rouch, Mathieu Verdurand, Christelle Mouchoux, Floriane Delphin-Combe, Sylvain Gaujard and Pierre Krolak-Salmon

    Citation: BMC Geriatrics 2019 19:191

    Content type: Study protocol

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  13. Dementia is a syndrome, with a wide range of symptoms. It is important to have a timely diagnosis during the disease course to reduce the risk of medication errors, enable future care planning for the patient ...

    Authors: Connie Lethin, Ingalill Rahm Hallberg, Anna Renom Guiteras, Hilde Verbeek, Kai Saks, Minna Stolt, Adelaida Zabalegui, Maria Soto-Martin and Christer Nilsson

    Citation: BMC Geriatrics 2019 19:172

    Content type: Research article

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  15. Dementia with Lewy bodies (DLB) is still underdiagnosed or mistaken for other types of neurodegenerative diseases. Biomarkers such as 18-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) can be helpful.

    Authors: Astrid Melani Suantio, Hian Liang Huang, Cecilia Sze Nga Kwok, Darren Cheng Han Teo and Minh Ha Nguyen

    Citation: BMC Geriatrics 2019 19:150

    Content type: Case report

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  16. Smartphone use has become an increasingly pervasive part of our daily lives, and as a portable media device, smartphones provide good support for cognitive training during aging. However, little is known about...

    Authors: Manqiong Yuan, Jia Chen, Zi Zhou, Jiahui Yin, Jielong Wu, Mingliang Luo, Lixia Wang and Ya Fang

    Citation: BMC Geriatrics 2019 19:140

    Content type: Research article

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  17. The main objective of this research was to evaluate the acceptance of technology based on a wearable lifelogging camera in a sample of older adults diagnosed with mild cognitive impairment (MCI).

    Authors: Olga Gelonch, Mireia Ribera, Núria Codern-Bové, Sílvia Ramos, Maria Quintana, Gloria Chico, Noemí Cerulla, Paula Lafarga, Petia Radeva and Maite Garolera

    Citation: BMC Geriatrics 2019 19:110

    Content type: Research article

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  18. Previous observational studies and clinical trials have shown that cholinesterase inhibitors (with or without memantine) provide benefit for patients with mild-to-moderate Alzheimer’s disease. However, the imp...

    Authors: Aina Soler, Guillem Amer, Alicia Leiva, Joana Ripoll, María Angeles Llorente, Alfonso Leiva, Joana Maria Taltavull, Rosa Molina and Joan Llobera

    Citation: BMC Geriatrics 2019 19:101

    Content type: Study protocol

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  19. The elderly, and especially those with an immuno-compromised status, are vulnerable to infectious diseases. The purpose of this study was to examine the clinical characteristics and therapeutic outcomes of cry...

    Authors: Wan-Chen Tsai, Chia-Yi Lien, Jun-Jun Lee, Wen-Chiu Hsiao, Chi-Ren Huang, Nai-Wen Tsai, Chiung-Chih Chang, Cheng-Hsien Lu and Wen-Neng Chang

    Citation: BMC Geriatrics 2019 19:91

    Content type: Research article

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  20. Older adults often suffer from age- and behavior-related brain changes affecting neuronal functioning and, therefore, cognitive and motor functions. The improvement of these functions might decrease falls and ...

    Authors: Alexandra Schättin, Corinne Baier, Domenique Mai, Verena Klamroth-Marganska, Isabelle Herter-Aeberli and Eling D. de Bruin

    Citation: BMC Geriatrics 2019 19:81

    Content type: Research article

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  21. Visual rating scales are still the most popular tools in assessing atrophy degrees of whole brain and lobes. However, the false negative rate of the previous cutoff score of visual rating scales was relatively...

    Authors: Mingqing Wei, Jing Shi, Jingnian Ni, Xuekai Zhang, Ting Li, Zilong Chen, Mengling Zhou, Liping Zhang, Zhongjian Tan, Yongyan Wang and Jinzhou Tian

    Citation: BMC Geriatrics 2019 19:59

    Content type: Research article

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  22. Stroke incidence has declined during the past decades. Yet, there is a concern that an ageing population together with improved survival after stroke will result in a raised proportion of the population who ha...

    Authors: Karin Modig, Mats Talbäck, Louise Ziegler and Anders Ahlbom

    Citation: BMC Geriatrics 2019 19:31

    Content type: Research article

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  23. Alterations in autonomic nervous system (ANS) activity might be involved in the pathophysiology of delirium. The aim was to explore autonomic cardiovascular control in older patients with and without delirium.

    Authors: Bjørn Erik Neerland, Torgeir Bruun Wyller and Vegard Bruun Bratholm Wyller

    Citation: BMC Geriatrics 2019 19:23

    Content type: Research article

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  24. Dementia patients often show neuropsychiatric symptoms, known as behavioral and psychological symptoms of dementia (BPSD). These are a common motive for medical consultations, hospitalizations, and nursing hom...

    Authors: Mireia Massot Mesquida, Montserrat Tristany Casas, Alicia Franzi Sisó, Isabel García Muñoz, Óscar Hernández Vian and Pere Torán Monserrat

    Citation: BMC Geriatrics 2019 19:7

    Content type: Research article

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  25. Aging and rural-urban disparities are two major social problems in today’s ever-developing China. Much of the existing literature has supported a negative association between adverse community setting with the...

    Authors: Yuanxi Xiang, Hossein Zare, Cuiling Guan and Darrell Gaskin

    Citation: BMC Geriatrics 2018 18:323

    Content type: Research article

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  26. The oldest-old (subjects aged 90 years and older) population represents the fastest growing segment of society and shows a high dementia prevalence rate of up to 40%. Only a few studies have investigated prote...

    Authors: Nienke Legdeur, Maryam Badissi, Stephen F. Carter, Sophie de Crom, Aleid van de Kreeke, Ralph Vreeswijk, Marijke C. Trappenburg, Mardien L. Oudega, Huiberdina L. Koek, Jos P. van Campen, Carolina J. P. W. Keijsers, Chinenye Amadi, Rainer Hinz, Mark F. Gordon, Gerald Novak, Jana Podhorna…

    Citation: BMC Geriatrics 2018 18:289

    Content type: Study protocol

    Published on:

  27. Patients with delirium have increased risk of death, dementia and institutionalization, and prognosis differs between delirium motor subtypes. A few studies have identified associations between environmental f...

    Authors: Sigurd Evensen, Ingvild Saltvedt, Stian Lydersen, Torgeir Bruun Wyller, Kristin Taraldsen and Olav Sletvold

    Citation: BMC Geriatrics 2018 18:282

    Content type: Research article

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  28. One of the crucial challenges for the future of therapeutic approaches to Alzheimer’s disease (AD) is to target the main pathological processes responsible for disability and dependency. However, a progressive...

    Authors: Nawele Boublay, Denis Fédérico, Alain Pesce, Marc Verny, Frédéric Blanc, Marc Paccalin, Thomas Desmidt, Pierre Grosmaître, Olivier Moreaud, Solveig Relland, Estelle Bravant, Romain Bouet and Pierre Krolak-Salmon

    Citation: BMC Geriatrics 2018 18:280

    Content type: Study protocol

    Published on:

  29. Dementia and physical morbidity are primary reasons for nursing home admission globally. However, data on physical morbidity in nursing home residents with and without dementia are scarce. The first aim of the...

    Authors: Live Bredholt Jørgensen, Berit Marie Thorleifsson, Geir Selbæk, Jūratė Šaltytė Benth and Anne-Sofie Helvik

    Citation: BMC Geriatrics 2018 18:254

    Content type: Research article

    Published on:

  30. The objective of this study was to examine patient characteristics and health care resource utilization (HCRU) in the 36 months prior to a confirmatory diagnosis of Alzheimer’s disease (AD) compared to a match...

    Authors: Radhika Nair, Virginia S. Haynes, Mir Siadaty, Nick C. Patel, Adam S. Fleisher, Derek Van Amerongen, Michael M. Witte, AnnCatherine M. Downing, Leslie Ann Hazel Fernandez, Vishal Saundankar and Daniel E. Ball

    Citation: BMC Geriatrics 2018 18:243

    Content type: Research article

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  31. The conventional scores of the neuropsychological batteries are not fully optimized for diagnosing dementia despite their variety and abundance of information. To achieve low-cost high-accuracy diagnose perfor...

    Authors: Hyun-Soo Choi, Jin Yeong Choe, Hanjoo Kim, Ji Won Han, Yeon Kyung Chi, Kayoung Kim, Jongwoo Hong, Taehyun Kim, Tae Hui Kim, Sungroh Yoon and Ki Woong Kim

    Citation: BMC Geriatrics 2018 18:234

    Content type: Research Article

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  32. Delirium is a common and serious clinical syndrome which is often missed in routine clinical care. The core cognitive feature is inattention. We developed a novel bedside neuropsychological test for assessing ...

    Authors: Lisa-Marie Rutter, Eva Nouzova, David J. Stott, Christopher J. Weir, Valentina Assi, Jennifer H. Barnett, Caoimhe Clarke, Nikki Duncan, Jonathan Evans, Samantha Green, Kirsty Hendry, Meigan McGinlay, Jenny McKeever, Duncan G. Middleton, Stuart Parks, Robert Shaw…

    Citation: BMC Geriatrics 2018 18:217

    Content type: Study protocol

    Published on:

  33. Driving is related to social participation; therefore older drivers may be reluctant to cease driving. Continuation of driving has also been reported in a large proportion of patients with cognitive impairment...

    Authors: Dafne Piersma, Anselm B. M. Fuermaier, Dick De Waard, Ragnhild J. Davidse, Jolieke De Groot, Michelle J. A. Doumen, Rudolf W. H. M. Ponds, Peter P. De Deyn, Wiebo H. Brouwer and Oliver Tucha

    Citation: BMC Geriatrics 2018 18:216

    Content type: Research Article

    Published on:

  34. Individuals with mild cognitive impairment (MCI) are at heightened risk of developing dementia. Rapid advances in computing technology have enabled researchers to conduct cognitive training and rehabilitation ...

    Authors: Shaoqing Ge, Zheng Zhu, Bei Wu and Eleanor S. McConnell

    Citation: BMC Geriatrics 2018 18:213

    Content type: Research article

    Published on:

  35. Cognition is a key factor in the regulation of normal walking and dual-task gait assessment is an accepted method to evaluate the relationship. The objective of this study was to create a framework for task co...

    Authors: Susan W. Hunter, Alison Divine, Courtney Frengopoulos and Manuel Montero Odasso

    Citation: BMC Geriatrics 2018 18:202

    Content type: Research article

    Published on:

  36. An association between handgrip strength, hand dexterity and global cognition is suggested; however, it is unclear whether both hand motor functions are associated with executive function, which is important f...

    Authors: Kimi Estela Kobayashi-Cuya, Ryota Sakurai, Naoko Sakuma, Hiroyuki Suzuki, Masashi Yasunaga, Susumu Ogawa, Toru Takebayashi and Yoshinori Fujiwara

    Citation: BMC Geriatrics 2018 18:192

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Geriatrics 2018 18:210

  37. Risk factors for cognitive decline might depend on chronological age. The aim of the study was to explore the age dependency of risk factors for cognitive decline in cognitively healthy subjects aged 55–85 yea...

    Authors: N. Legdeur, M. W. Heymans, H. C. Comijs, M. Huisman, A. B. Maier and P. J. Visser

    Citation: BMC Geriatrics 2018 18:187

    Content type: Research article

    Published on:

  38. The risk-benefit relationship of memantine treatment for Alzheimer’s disease (AD) remains unclear. In addition, variability between the results of clinical trials has been observed. The aim of this study was t...

    Authors: Lídia Blanco-Silvente, Dolors Capellà, Josep Garre-Olmo, Joan Vilalta-Franch and Xavier Castells

    Citation: BMC Geriatrics 2018 18:168

    Content type: Research article

    Published on:

  40. Late-life cognitive decline, caused by progressive neuronal loss leading to brain atrophy years before symptoms are detected, is expected to double in Canada over the next two decades. Cognitive impairment in ...

    Authors: Sana Tariq, Christopher D. d’Esterre, Tolulope T. Sajobi, Eric E. Smith, Richard Stewart Longman, Richard Frayne, Shelagh B. Coutts, Nils D. Forkert and Philip A. Barber

    Citation: BMC Geriatrics 2018 18:163

    Content type: Study protocol

    Published on:

  41. The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) is widely used as a complementary screening tool for dementia. However, there are few studies concerning the efficacy of the IQCODE for ...

    Authors: Yunlong Ding, Jiali Niu, Yanrong Zhang, Wenpeng Liu, Yan Zhou, Can Wei and Yan Liu

    Citation: BMC Geriatrics 2018 18:146

    Content type: Research article

    Published on:

  42. Alzheimer’s disease (AD) dementia, a progressive neurodegenerative disease, exerts significant burden upon patients, caregivers, and healthcare systems globally. The current study investigated the associations...

    Authors: William Montgomery, Amir Goren, Kristin Kahle-Wrobleski, Tomomi Nakamura and Kaname Ueda

    Citation: BMC Geriatrics 2018 18:141

    Content type: Research article

    Published on:

  43. Community health professionals play a significant role in dementia care. However, little is known about community health professionals’ capacity in dementia care, especially in low and middle-income countries....

    Authors: Yao Wang, Lily Dongxia Xiao, Yang Luo, Shui-Yuan Xiao, Craig Whitehead and Owen Davies

    Citation: BMC Geriatrics 2018 18:122

    Content type: Research article

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  44. Vascular risk factors increase the risk of Alzheimer’s disease (AD), but there is limited evidence on whether comorbid vascular conditions and risk factors have an impact on disease progression. The aim of thi...

    Authors: Rannveig Sakshaug Eldholm, Karin Persson, Maria Lage Barca, Anne-Brita Knapskog, Lena Cavallin, Knut Engedal, Geir Selbaek, Eva Skovlund and Ingvild Saltvedt

    Citation: BMC Geriatrics 2018 18:120

    Content type: Research article

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  45. There are effective non-pharmacological treatment programs that reduce functional disability and changed behaviours in people with dementia. However, these programs (such as the Care of People with dementia in...

    Authors: Lindy Clemson, Kate Laver, Yun-Hee Jeon, Tracy A Comans, Justin Scanlan, Miia Rahja, Jennifer Culph, Lee-Fay Low, Sally Day, Monica Cations, Maria Crotty, Susan Kurrle, Catherine Piersol and Laura N. Gitlin

    Citation: BMC Geriatrics 2018 18:108

    Content type: Study protocol

    Published on:

  46. Self-rated health predicts health outcomes independently of levels of disability or mood. Little is known about what influences the subjective health experience of stroke survivors. Our aim was to investigate ...

    Authors: N. Mavaddat, E. Sadler, L. Lim, K. Williams, E. Warburton, A. L. Kinmonth, J. Mant, J. Burt and C. McKevitt

    Citation: BMC Geriatrics 2018 18:81

    Content type: Research Article

    Published on:

  47. Many older adults have low levels of health literacy which affects their ability to participate optimally in healthcare. It is unclear how cognitive decline contributes to health literacy. To study this, longi...

    Authors: Bas Geboers, Ellen Uiters, Sijmen A. Reijneveld, Carel J. M. Jansen, Josué Almansa, Astrid C. J. Nooyens, W. M. Monique Verschuren, Andrea F. de Winter and H. Susan J. Picavet

    Citation: BMC Geriatrics 2018 18:77

    Content type: Research article

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  49. Elderly persons with a dementia diagnosis often suffer from different neuropsychiatric symptoms (NPS) such as delusions, hallucinations, depression, anxiety, irritability and agitation. Currently, the medical ...

    Authors: Iris Zahirovic, Gustav Torisson, Carina Wattmo and Elisabet Londos

    Citation: BMC Geriatrics 2018 18:50

    Content type: Research Article

    Published on:

  50. It has been suggested that tooth loss in later life might increase dementia incidence. The objective of this analysis is to systematically review the current evidence on the relationship between the number of ...

    Authors: Bumjo Oh, Dong-Hun Han, Kyu-Tae Han, Xibei Liu, Johnson Ukken, Carina Chang, Kiki Dounis and Ji Won Yoo

    Citation: BMC Geriatrics 2018 18:48

    Content type: Research Article

    Published on:

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