Biology and technology

Section edited by John Tower

This section considers all manuscripts on biomarkers, biological mechanisms, diagnostic instruments, use of technology in geriatric settings, biology of ageing, genetics.

Previous Page Page 1 of 2 Next Page
  1. Research Article

    Association between routine laboratory tests and long-term mortality among acutely admitted older medical patients: a cohort study

    Older people have the highest incidence of acute medical admissions. Old age and acute hospital admissions are associated with a high risk of adverse health outcomes after discharge, such as reduced physical p...

    Henrik Hedegaard Klausen, Janne Petersen, Thomas Bandholm, Helle Gybel Juul-Larsen, Juliette Tavenier, Jesper Eugen-Olsen and Ove Andersen

    BMC Geriatrics 2017 17:62

    Published on: 1 March 2017

    The Erratum to this article has been published in BMC Geriatrics 2017 17:67

  2. Commentary

    Problems of video-based pain detection in patients with dementia: a road map to an interdisciplinary solution

    Given the unreliable self-report in patients with dementia, pain assessment should also rely on the observation of pain behaviors, such as facial expressions. Ideal observers should be well trained and should ...

    Miriam Kunz, Dominik Seuss, Teena Hassan, Jens U. Garbas, Michael Siebers, Ute Schmid, Michael Schöberl and Stefan Lautenbacher

    BMC Geriatrics 2017 17:33

    Published on: 26 January 2017

  3. Research Article

    Potential unfavorable impacts of BDNF Val66Met polymorphisms on metabolic risks in average population in a longevous area

    Brain-derived neurotrophic factor (BDNF) has been implicated in cognitive performance and the modulation of several metabolic parameters in some disease models, but its potential roles in successful aging rema...

    Jun-Hua Peng, Cheng-Wu Liu, Shang-Ling Pan, Hua-Yu Wu, Qing-Hua Liang, Rui-Jing Gan, Ling Huang, Yi Ding, Zhang-Ya Bian, Hao Huang, Ze-Ping Lv, Xiao-Ling Zhou and Rui-Xing Yin

    BMC Geriatrics 2017 17:4

    Published on: 5 January 2017

  4. Research article

    Prevalent peripheral arterial disease and inflammatory burden

    Strong evidence implicates inflammation in the development of atherosclerotic heart disease but less is known about peripheral arterial disease (PAD). Our objective was to test the hypothesis that a composite ...

    Jane A. Cauley, Ahmed M. Kassem, Nancy E. Lane and Sara Thorson

    BMC Geriatrics 2016 16:213

    Published on: 9 December 2016

  5. Research Article

    miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans

    In mammals, the IGF-1 pathway affects the phenotype of aging. Since the function of the immune system is modulated by IGF-1, it is plausible that immunosenescence might in part result from altered control by t...

    Monika Budzinska, Magdalena Owczarz, Eliza Pawlik-Pachucka, Malgorzata Roszkowska-Gancarz, Przemyslaw Slusarczyk and Monika Puzianowska-Kuznicka

    BMC Geriatrics 2016 16:200

    Published on: 30 November 2016

  6. Research article

    Clinical evaluation of an over-the-counter hearing aid (TEO First®) in elderly patients suffering of mild to moderate hearing loss

    Presbycusis has a direct influence on autonomy of the elderly but hearing aids lack of affordability. Moreover a recent review demonstrate that electroacoustic characteristics of OTC hearing aids were generall...

    Guillaume Sacco, Sébastien Gonfrier, Bernard Teboul, Ivan Gahide, Fredéric Prate, Mathilde Demory-Zory, Jean-Michel Turpin, Claire Vuagnoux, Philippe Genovese, Stéphane Schneider, Olivier Guérin and Nicolas Guevara

    BMC Geriatrics 2016 16:136

    Published on: 9 July 2016

  7. Research article

    Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study

    The Long Life Family Study (LLFS) is an international study to identify the genetic components of various healthy aging phenotypes. We hypothesized that pedigree-specific rare variants at longevity-associated ...

    Todd E. Druley, Lihua Wang, Shiow J. Lin, Joseph H. Lee, Qunyuan Zhang, E. Warwick Daw, Haley J. Abel, Sara E. Chasnoff, Enrique I. Ramos, Benjamin T. Levinson, Bharat Thyagarajan, Anne B. Newman, Kaare Christensen, Richard Mayeux and Michael A. Province

    BMC Geriatrics 2016 16:80

    Published on: 9 April 2016

  8. Research article

    The association of serum procalcitonin and high-sensitivity C-reactive protein with pneumonia in elderly multimorbid patients with respiratory symptoms: retrospective cohort study

    Serum procalcitonin and high-sensitivity C-reactive protein (hs-CRP) elevations have been associated with pneumonia in adults. Our aim was to establish their diagnostic usefulness in a cohort of hospitalized m...

    Antonio Nouvenne, Andrea Ticinesi, Giuseppina Folesani, Nicoletta Cerundolo, Beatrice Prati, Ilaria Morelli, Loredana Guida, Fulvio Lauretani, Marcello Maggio, Rosalia Aloe, Giuseppe Lippi and Tiziana Meschi

    BMC Geriatrics 2016 16:16

    Published on: 15 January 2016

  9. Research article

    Association of complete blood cell counts with metabolic syndrome in an elderly population

    Metabolic syndrome’s (MetS) role in predicting cardiovascular diseases and diabetes has been confirmed in many large cohort studies. Nontraditionally, hematogram components are significantly related to MetS in...

    Peng-Fei Li, Jin-Shuen Chen, Jin-Biou Chang, Hsiao-Wen Chang, Chung-Ze Wu, Tsung-Ju Chuang, Chia-Luen Huang, Dee Pei, Chang-Hsun Hsieh and Yen-Lin Chen

    BMC Geriatrics 2016 16:10

    Published on: 13 January 2016

  10. Research article

    Using diffusion of innovation theory to describe perceptions of a passive positioning alarm among persons with mild dementia: a repeated interview study

    Problems with memory and decline in cognitive abilities are common during development of dementia. Different kinds of technologies may be useful in supporting persons with dementia and their relatives in daily...

    Annakarin Olsson, Kirsti Skovdahl and Maria Engström

    BMC Geriatrics 2016 16:3

    Published on: 8 January 2016

  11. Research article

    Relationship between biomarkers of inflammation, oxidative stress and endothelial/microcirculatory function in successful aging versus healthy youth: a transversal study

    There is a functional decline of endothelial- dependent vasodilatation in the aging process. The aims of this study were to investigate if various microcirculatory parameters could correlate to anthropometrica...

    Daniel Alexandre Bottino, Flávia Gomes Lopes, Francisco José de Oliveira, Anete de Souza Mecenas, Ruth Clapauch and Eliete Bouskela

    BMC Geriatrics 2015 15:41

    Published on: 8 April 2015

  12. Research article

    Interleukin-6 concentrations in the urine and dipstick analyses were related to bacteriuria but not symptoms in the elderly: a cross sectional study of 421 nursing home residents

    Up to half the residents of nursing homes for the elderly have asymptomatic bacteriuria (ABU), which should not be treated with antibiotics. A complementary test to discriminate between symptomatic urinary tra...

    Pär-Daniel Sundvall, Marie Elm, Peter Ulleryd, Sigvard Mölstad, Nils Rodhe, Lars Jonsson, Bengt Andersson, Mirjana Hahn-Zoric and Ronny Gunnarsson

    BMC Geriatrics 2014 14:88

    Published on: 12 August 2014

  13. Research article

    A systematic review of the evidence that brain structure is related to muscle structure and their relationship to brain and muscle function in humans over the lifecourse

    An association between cognition and physical function has been shown to exist but the roles of muscle and brain structure in this relationship are not fully understood. A greater understanding of these relati...

    Alixe HM Kilgour, Oliver M Todd and John M Starr

    BMC Geriatrics 2014 14:85

    Published on: 10 July 2014

  14. Research article

    Clinical and inflammatory response to bloodstream infections in octogenarians

    Given the increasing incidence of bacteraemia causing significant morbidity and mortality in older patients, this study aimed to compare the clinical features, laboratory findings and mortality of patients ove...

    Jessica Emily Green, Yohanes Ariathianto, Si Mun Wong, Craig Aboltins and Kwang Lim

    BMC Geriatrics 2014 14:55

    Published on: 23 April 2014

  15. Research article

    Immunosenescence in the nursing home elderly

    To describe T-cell and natural killer (NK) cell phenotypes within nursing home elderly.

    Jennie Johnstone, Jamie Millar, Alina Lelic, Chris P Verschoor, Stephen D Walter, Philip J Devereaux, Jonathan Bramson and Mark Loeb

    BMC Geriatrics 2014 14:50

    Published on: 17 April 2014

  16. Research article

    PML-nuclear bodies decrease with age and their stress response is impaired in aged individuals

    Promyelocytic leukemia nuclear bodies (PML-NBs) have been depicted as structures which are involved in processing cell damages and DNA double-strand break repairs. The study was designed to evaluate difference...

    Barbara Wenger, Manuela Schwegler, Maria Brunner, Christoph Daniel, Manfred Schmidt, Rainer Fietkau and Luitpold V Distel

    BMC Geriatrics 2014 14:42

    Published on: 2 April 2014

Previous Page Page 1 of 2 Next Page