| N | Q1 | Q2 | Q3 | Q4 | P for trend | P for interaction |
---|---|---|---|---|---|---|---|
Total | 7036 | Ref | 0.84 (0.72, 0.98) | 0.70 (0.58, 0.84) | 0.46 (0.35, 0.61) |  < 0.001 | — |
Gendera | Â | Â | Â | Â | Â | Â | 0.034 |
 Male | 3358 (47.7%) | Ref | 0.62 (0.34, 1.15) | 0.49 (0.28, 0.86) | 0.32 (0.19, 0.55) |  < 0.001 |  |
 Female | 3678 (52.3%) | Ref | 0.85 (0.73, 1.00) | 0.72 (0.58, 0.89) | 0.56 (0.36, 0.88) |  < 0.001 |  |
Age (y) | Â | Â | Â | Â | Â | Â | 0.372 |
 [60, 70] | 4572 (65.0%) | Ref | 0.81 (0.67, 0.98) | 0.71 (0.56, 0.90) | 0.43 (0.30, 0.61) |  < 0.001 |  |
  > 70 | 2464 (35.0%) | Ref | 0.91 (0.70, 1.19) | 0.68 (0.49, 0.94) | 0.52 (0.33, 0.83) | 0.003 |  |
Marriage | Â | Â | Â | Â | Â | Â | 0.718 |
 Married | 6227 (88.5%) | Ref | 0.83 (0.70, 0.99) | 0.69 (0.56, 0.85) | 0.47 (0.35, 0.63) |  < 0.001 |  |
 Single | 809 (11.5%) | Ref | 0.86 (0.58, 1.29) | 0.75 (0.40, 1.42) | 0.33 (0.11, 1.02) | 0.076 |  |
BMI (kg/m2) | Â | Â | Â | Â | Â | Â | 0.625 |
  ≤ 18.4 | 351 (5.0%) | Ref | 0.63 (0.29, 1.38) | 0.36 (0.10, 1.30) | 0.35 (0.07, 1.79) | 0.074 |  |
 18.5–23.9 | 3263 (46.7%) | Ref | 0.87 (0.69, 1.09) | 0.72 (0.53, 0.97) | 0.49 (0.32, 0.76) | 0.001 |  |
  ≥ 24.0 | 3377 (48.3%) | Ref | 0.83 (0.67, 1.04) | 0.70 (0.54, 0.90) | 0.45 (0.30, 0.65) |  < 0.001 |  |
Sleep (h) | Â | Â | Â | Â | Â | Â | 0.686 |
  ≤ 6 | 3384 (48.6%) | Ref | 0.88 (0.71, 1.09) | 0.71 (0.55, 0.93) | 0.54 (0.37, 0.79) | 0.001 |  |
  > 6 | 3583 (51.4%) | Ref | 0.79 (0.62, 1.00) | 0.68 (0.51, 0.91) | 0.39 (0.26, 0.59) |  < 0.001 |  |
Comorbidities | Â | Â | Â | Â | Â | Â | 0.833 |
 None | 6933 (98.5%) | Ref | 0.83 (0.71, 0.97) | 0.69 (0.57, 0.84) | 0.46 (0.35, 0.61) |  < 0.001 |  |
 At least one | 103 (1.5%) | Ref | 2.11 (0.37, 12.21) | 1.08 (0.11, 10.44) | 0.44 (0.03, 6.34) | 0.608 |  |