Table 1 Characteristics of the study population according to frailty assessed by FI-Lab
Variables | Robust(n = 261) | Pre-frailty(n = 395) | Frailty(n = 508) | P |
|---|---|---|---|---|
Age(years) | 71.0(67.0,76.5) | 77.0(70.0,83.0) | 77.0(71.0,84.0) | < 0.001 |
Female,n(%) | 136(52.1) | 154(39.0) | 148(29.1) | < 0.001 |
BMI(kg/m2) | 24.2(21.8,26.0) | 22.78(19.9,25.1) | 22.04(19.8,24.8) | < 0.001 |
Smoking history,n(%) | 0.713 | |||
No | 194(74.3) | 294(74.4) | 367(72.2) | |
Yes | 67(25.7) | 101(25.6) | 141(27.8) | |
Drinking history,n(%) | 0.468 | |||
No | 222(85.1) | 348(88.1) | 436(85.8) | |
Yes | 39(14.7) | 47(11.9) | 72(14.2) | |
WBC(× 10^9/L) | 5.8(4.9,7.2) | 7.0(5.3,8.5) | 8.6(5.9,11.9) | < 0.001 |
LYMPH(× 10^9/L) | 1.5(1.2,1.9) | 1.1(0.8,1.6) | 0.9(0.6,1.2) | < 0.001 |
NEUT(× 10^9/L) | 3.6(2.8,4.7) | 4.9(3.5,6.4) | 6.8(4.2,10.0) | < 0.001 |
eGFR(ml/min) | 84.0(72.0,91.0) | 83.0(65.0,91.0) | 72.0(30.0,91.0) | < 0.001 |
hs-CRP(mg/L) | 5.0(3.1,19.7) | 30.0(7.3,59.9) | 67.6(31.7,101.0) | < 0.001 |
PCT(ng/ml) | 0.08(0.04,0.10) | 0.10(0.05,0.21) | 0.39(0.13,1.44) | < 0.001 |
aCCI | 4(3,5) | 5(4,6) | 6(4,8) | < 0.001 |
CURB-65 | 1(1,1) | 1(1,2) | 2(1,2) | < 0.001 |
LOS(days) | 8.0(6.0,11.0) | 11.0(8.0,15.0) | 12.0(8.0,18.0) | < 0.001 |
Duration of antibiotic therapy | 7.0(5.0,9.0) | 9.0(7.0,13.0) | 11.0(7.0,15.0) | < 0.001 |
Death,n(%) | 29(11.1) | 112(28.4) | 267(52.6) | < 0.001 |