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Table 1 Main trial characteristics of all included RCTs and trials specifically designed for older people

From: Temporal changes in characteristics and external validity of randomized controlled trials in older people from 2012 to 2019

 

Main trial characteristics

All included trials

Trials specifically designed for older people

2012

n = 1369

2019

N = 1446

2012

N = 96

2019

N = 116

Number of participants N, (median, IQR)

82 (40–215

84 (48–182)

125 (48–316)

104 (50–241)

Age of participants, years (median, IQR)

46 (29–60)

46.5 (28.5–60.5)

73 (71–77)

72 (70–74.5)

Lower cut-off value for age, years (median, IQR)

18 (18–20)

18 (18–20)

65 (49–65)

60 (50–65)

  1. Trials were classified as specifically designed for older people if minimum trial participant age ≥ 55 years, or if mean trial participant age ≥ 70 years
  2. Medians and interquartile ranges (difference between 25 and 75th percentile) are reported
  3. Abbreviations: RCT Randomized controlled trial, IQR Interquartile range