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Table 1 Etiological classification of rapidly progressive dementia participants in this study

From: Prevalence and outcomes of rapidly progressive dementia: a retrospective cohort study in a neurologic unit in China

Etiology

Number (%)

Age (years)

Education level

Baseline MMSE value

Infectious entities

39 (26.2%)

56.1 ± 14.5

6, 9, 22

13.1 ± 4.6

Creutzfeldt-Jakob disease

20 (13.4%)

   

Neurosyphilis

8 (5.4%)

   

Other infections entities

11 (7.4%)

   

Neurodegenerative entities

31 (20.8%)

68.4 ± 10.8

8, 6, 16

11.2 ± 4.0

Alzheimer’s disease

17 (11.4%)

   

Dementia with Lewy body

8 (5.4%)

   

Neuronal intranuclear inclusion disease

4 (2.7%)

   

Frontotemporal lobar degeneration

2 (1.4%)

   

Toxic/metabolic entities

25 (16.8%)

53.1 ± 12.7

3, 3, 18

12.4 ± 5.5

Carbon monoxide poisoning

12 (8.1%)

   

Heroin poisoning

1 (0.7%)

   

Dichloroethane poisoning

1 (0.7%)

   

Alcohol poisoning

2 (1.3%)

   

Other toxic entities

2 (1.3%)

   

Mitochondrial encephalopathy

2 (1.3%)

   

Wernicke encephalopathy

1 (0.7%)

   

Hashimoto encephalopathy

1 (0.7%)

   

Radiation encephalopathy

1 (0.7%)

   

Other metabolic entities

2 (1.3%)

   

Inflammatory entities

15 (10.1%)

51.1 ± 13.7

1, 5, 8

13.8 ± 4.6

Anti-AMPA2 receptor encephalitis

3 (2.0%)

   

Anti-LG1 receptor encephalitis

3 (2.0%)

   

Limbic encephalitis

2 (1.3%)

   

Anti-GABAB receptor encephalitis

1 (0.7%)

   

Central demyelinating disease

2 (1.3%)

   

Sjogren’s syndrome with central involvement

1 (0.7%)

   

Other inflammatory entities

3 (2.0%)

   

Vascular entities

13 (8.7%)

63.1 ± 12.8

1, 5, 7

14.6 ± 4.3

Other entities

11 (7.4%)

55.0 ± 17.4

2, 3, 6

15.0 ± 3.6

Mixed entities

5 (3.4%)

72.6 ± 9.1

1, 3, 1

12.2 ± 6.5

Neoplastic entities

5 (3.4%)

53.8 ± 13.1

0, 3, 2

14.3 ± 2.1

Undetermined entities

5 (3.4%)

54.8 ± 27.1

1, 1, 3

16.0 ± 1.0

  1. Note: Age and baseline MMSE value are presented as mean ± standard deviation, education level is presented as numbers of no education, 1 to 6 years of education and more than 6 years of education
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BMC Geriatrics

ISSN: 1471-2318

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