Physical activity levels in cognitively normal and cognitively impaired oldest-old and the association with dementia risk factors: a pilot study

Table 2 Associations between physical activity measures and risk factors for dementia in cognitively normal oldest-old individuals

	Total active duration	Total sedentary duration	Number of sitting bouts	Maximum walking bout duration	MI moving
Grip strength	0.13 (0.11), p = 0.27	-0.13 (0.10), p = 0.24	0.27 (0.09), p = 0.02*	0.10 (0.10), p = 0.45	0.22 (0.11), p = 0.08
Muscle mass	-0.16 (0.12), p = 0.27	0.24 (0.11), p = 0.05	-0.14 (0.11), p = 0.24	-0.03 (0.12), p = 0.84	0.09 (0.13), p = 0.54
SPPB	0.34 (0.13), p = 0.057	-0.20 (0.13), p = 0.16	0.24 (0.12), p = 0.13	0.35 (0.12), p = 0.04*	0.56 (0.12), p < 0.001***
MNA	0.33 (0.15), p = 0.08	-0.41 (0.14), p = 0.02*	0.30 (0.14), p = 0.10	0.39 (0.14), p = 0.04*	0.41 (0.15), p = 0.04*
BMI	-0.46 (0.16), p = 0.04*	0.51 (0.14), p = 0.006**	-0.46 (0.14), p = 0.02*	-0.25 (0.16), p = 0.23	-0.17 (0.17), p = 0.44
WMH	-0.16 (0.19), p = 0.40	0.11 (0.18), p = 0.54	-0.20 (0.17), p = 0.26	-0.24 (0.19), p = 0.32	-0.43 (0.17), p = 0.04*
Hippocampal volume	0.20 (0.15), p = 0.27	-0.26 (0.14), p = 0.12	0.18 (0.14), p = 0.24	0.10 (0.16), p = 0.61	0.18 (0.15), p = 0.38
Amyloid binding	0.39 (0.17), p = 0.08	-0.41 (0.17), p = 0.05	0.25 (0.18), p = 0.24	0.45 (0.18), p = 0.049*	0.12 (0.21), p = 0.56

Note. Outcomes are given as β(SE). P-values are FDR corrected. All variables are z-transformed, so that betas are comparable between variables. All analyses are corrected for age, sex and years of education. Abbreviations: BMI, Body Mass Index; MNA, Mini-Nutritional Assessment; SPPB, Short Physical Performance Battery; MI, Movement Intensity; WMH, White Matter Hyperintensities. *p < 0.05, **p < 0.01, ***p < 0.001.

ISSN: 1471-2318