Table 1 Characteristics of studies included in the analysis
Study | Sample size | Groups | Participants | NIRS device | Surgery type | Assessment methods | Assessment timeline | Definition of cerebral desaturation | Quality of the evidence (GRADE) |
|---|---|---|---|---|---|---|---|---|---|
Yang et al., 2021 [7] | 26 | IG (n = 12) CG (n = 14) | > 65 yr | Masimo | spinal surgery | MoCA | pre-surgery, postoperative 7 d | a drop of more than 20% from baseline value | ⊕⊕⊕⊕ High |
Jing et al., 2021 [28] | 60 | IG (n = 30) CG (n = 30) | > 60 yr | OXImeter | shoulder arthroscopic surgery | MMSE, MoCA | pre-surgery, postoperative 1–3 d | a drop of more than 20% from baseline value or rSO2 less than 50% | ⊕⊕⊕○ Moderate |
Kunst et al., 2020 [29] | 82 | IG (n = 42) CG (n = 40) | > 65 yr | INVOS | CABG | MMSE | pre-surgery, postoperative 3–5 d | a drop of more than 15% from baseline value or rSO2 less than 50% | ⊕⊕⊕⊕ High |
Şahan et al., 2018 [30] | 40 | IG (n = 19) CG (n = 21) | > 60 yr | INVOS 5100 C | CABG | MMSE, WMS, CDT, WLGT, DSS, VSST | pre-surgery, postoperative 7 d, postoperative 3 m | a drop of more than 20% from baseline value or rSO2 less than 50% | ⊕⊕⊕⊕ High |
Ballard et al., 2012 [6] | 47 | IG (n = 19) CG (n = 28) | > 60 yr | INVOS | Orthopedic, abdominal surgery | MMSE | pre-surgery, postoperative 7 d | a drop of more than 15% from baseline value or rSO2 less than 50% | ⊕⊕○○ Low |
Casati et al., 2005 [27] | 122 | IG (n = 56) CG (n = 66) | > 65 yr | INVOS 4100 | major abdominal, nonvascular surgery | MMSE | pre-surgery, postoperative 7 d | a drop of more than 25% from baseline value (20% in case of baseline rSO2 < 50%) for ≥ 15 s. | ⊕⊕⊕○ Moderate |