Clinical outcomes | Total | Frequent exacerbators | Non-frequent exacerbators | |||
---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | |
Respiratory failure | ||||||
  low SI (ref) | 1 | 1 | 1 | 1 | 1 | 1 |
  high SI | 0.24(0.14–0.44) ** | 0.27(0.13–0.56) ** | 0.41(0.18–0.92) ** | 0.19(0.06–0.64) ** | 0.35(0.15–0.81) * | 0.31(0.11–0.85) * |
Heart failure | ||||||
  low SI (ref) | 1 | 1 | 1 | 1 | 1 | 1 |
  high SI | 0.55(0.3–1) | 0.84(0.39–1.79) | 1.1(0.46–2.65) | 1.11(0.32–3.88) | 0.48(0.2–1.14) | 0.42(0.13–1.35) |
Severe pneumonia | ||||||
  low SI (ref) | 1 | 1 | 1 | 1 | 1 | 1 |
  high SI | 0.38(0.15–0.95) * | 0.44(0.15–1.31) | 0.62(0.21–1.9) | 0.14(0.02–1.13) | 0.79(0.21–3.04) | 0.53(0.08–3.6) |
Invasive mechanical ventilation, n(%) | ||||||
  low SI (ref) | 1 | 1 | 1 | 1 | 1 | 1 |
  high SI | 0.41(0.15–1.08) | 0.45(0.13–1.5) | 0.46(0.13–1.63) | 0.02(0–1.1) | 1(0.24–4.11) | 2.62(0.24–29.08) |
Mortality, n(%) | ||||||
  low SI (ref) | 1 | 1 | 1 | 1 | 1 | 1 |
  high SI | NA | NA | NA | NA | NA | NA |