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Table 3 Associations between the sarcopenia index and clinical outcomes

From: Sarcopenia index as a predictor of clinical outcomes among older adult patients with acute exacerbation of chronic obstructive pulmonary disease: a cross-sectional study

Clinical outcomes

Total

Frequent exacerbators

Non-frequent exacerbators

Model 1

Model 2

Model 1

Model 2

Model 1

Model 2

Respiratory failure

  low SI (ref)

1

1

1

1

1

1

  high SI

0.24(0.14–0.44) **

0.27(0.13–0.56) **

0.41(0.18–0.92) **

0.19(0.06–0.64) **

0.35(0.15–0.81) *

0.31(0.11–0.85) *

Heart failure

  low SI (ref)

1

1

1

1

1

1

  high SI

0.55(0.3–1)

0.84(0.39–1.79)

1.1(0.46–2.65)

1.11(0.32–3.88)

0.48(0.2–1.14)

0.42(0.13–1.35)

Severe pneumonia

  low SI (ref)

1

1

1

1

1

1

  high SI

0.38(0.15–0.95) *

0.44(0.15–1.31)

0.62(0.21–1.9)

0.14(0.02–1.13)

0.79(0.21–3.04)

0.53(0.08–3.6)

Invasive mechanical ventilation, n(%)

  low SI (ref)

1

1

1

1

1

1

  high SI

0.41(0.15–1.08)

0.45(0.13–1.5)

0.46(0.13–1.63)

0.02(0–1.1)

1(0.24–4.11)

2.62(0.24–29.08)

Mortality, n(%)

  low SI (ref)

1

1

1

1

1

1

  high SI

NA

NA

NA

NA

NA

NA

  1. SI Sarcopenia index,re: Reference
  2. NA: unable to analyze owing to few outcome events
  3. Model 1: non-adjusted model. Model 2: adjusted for age, sex, smoking history, BMI, FEV1% predicted, WBC, CRP, ALB, GOLD grade (severity grading of COPD), CAT score, mMRC score, and comorbidities (diabetes, hypertension, coronary disease, arrhythmia)
  4. * P < 0.05, **P < 0.01