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Table 6 Multivariable analysis of raleted factors associated with PIM and MRP

From: A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional study

Variable

PIM

MRP

Inappropriate Medication Use

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

Age

1.002 (0.955–1.052)

0.935

0.988 (0.964–1.013)

0.344

1.024(0.966–1.086)

0.428

Gender (male)

0.810 (0.432–1.519)

0.511

1.448 (1.057–1.983)

0.021

1.035(0.499–2.150)

0.926

Department

 Cardiology

1.000

 

1.000

 

1.000

 

 Geriatrics

0.361 (0.101–1.283)

0.115

3.674 (2.089–6.459)

 < .001

0.668(0.121–3.683)

0.643

 Endocrinology

0.085 (0.029–0.247)

 < .001

1.323 (0.728–2.405)

0.358

0.068(0.020–0.230)

0.000

 Neurology

0.372 (0.132–1.052)

0.062

2.274 (1.451–3.566)

 < .001

0.477(0.146–1.566)

0.223

Health insurance

0.745 (0.271–2.046)

0.568

0.881 (0.529–1.467)

0.626

0.577(0.165–2.016)

0.389

Length of hospital stay

1.019 (0.940–1.106)

0.641

0.999 (0.961–1.038)

0.948

1.007(0.917–1.107)

0.878

CCI

1.114 (0.865–1.434)

0.403

0.961 (0.853–1.082)

0.511

1.193(0.868–1.639)

0.276

Number of diagnoses at discharge

0.970 (0.868–1.084)

0.589

1.016 (0.962–1.072)

0.578

1.007(0.881–1.150)

0.924

Number of drugs

 5–9

1.000

 

1.000

 

1.000

 

  ≥ 10

2.653 (1.275–5.522)

0.009

1.583 (1.114–2.248)

0.010

3.736(1.541–9.058)

0.004

Chronic conditions

 Hypertension

1.138 (0.568–2.278)

0.716

0.982 (0.672–1.435)

0.925

0.838(0.365–1.922)

0.676

 Type 2 diabetes

0.524 (0.237–1.158)

0.110

1.149 (0.800–1.649)

0.452

0.500(0.195–1.283)

0.150

 Coronary heart disease

3.002 (1.407–6.408)

0.004

1.141 (0.796–1.638)

0.472

2.620(1.090–6.297)

0.031

 Cerebral infarction

1.152 (0.562–2.359)

0.699

1.023 (0.713–1.468)

0.901

1.051(0.442–2.496)

0.991

 Hyperlipidemia

1.531 (0.793–2.958)

0.205

0.540 (0.386–0.756)

 < .001

1.400(0.651–3.013)

0.389

  1. PIM potential inappropriate medication, MRP medication related problem, CCI Charlson comorbidity index, Inappropriate Medication Use refers to the occurrence of either PIM or MRP; PIM was identified from either Beers or STOPP criteria