Table 1 Frailty, comorbidity, geriatric syndromes, mortality, and QOL in older adults with HIV by sex
Total | Men | Women | p | |
|---|---|---|---|---|
Patients. N (%) | 796 | 602 (75.9) | 194 (24.1) | |
Frailty | ||||
Frailty. N (%) | 46 (5.8) | 35 (5.8) | 11 (5.7) | 1 |
Prefrailty. N (%) | 417 (52.7) | 311 (51.6) | 106 (54.6) | 0.50 |
Comorbidity | ||||
≥ 3 comorbidities. N (%) | 306 (38.4) | 218 (36.2) | 88 (45.4) | 0.02 |
Hypertension. N (%) | 228 (28.7) | 182 (30.2) | 46 (23.8) | 0.09 |
Type 2 Diabetes. N (%) | 107 (13.5) | 89 (14.9) | 18 (9.3) | 0.04 |
Dyslipidemia. N (%) | 348 (43.8) | 259 (43.2) | 89 (45.9) | 0.50 |
Osteoarthritis. N (%) | 167 (21.2) | 102 (17.1) | 65 (34) | 0.01 |
Chronic renal failure. N (%) | 50 (6.3) | 40 (6.7) | 10 (5.2) | 0.60 |
Cancer. N (%) | 55 (6.9) | 43 (7.2) | 12 (6.2) | 0.70 |
History of cancer. N (%) | 59 (7.4) | 34 (5.7) | 25 (12.9) | 0.01 |
COPD. N (%) | 87 (11) | 63 (10.5) | 24 (12.5) | 0.40 |
Psychiatric disorders. N (%) | 73 (9.3) | 51 (8.6) | 22 (11.4) | 0.20 |
Geriatric Syndromes | ||||
≥ 1 geriatric syndrome. N (%) | 389 (48.9) | 272 (45.2) | 117 (60.3) | 0.01 |
Falls. N (%) | 124 (15.6) | 81 (13.5) | 43 (22.2) | 0.01 |
Depression. N (%) | 213 (26.8) | 153 (25.5) | 60 (30.9) | 0.10 |
Cognitive impairment. N (%) | 96 (12.1) | 71 (11.8) | 25 (12.9) | 0.70 |
Malnutrition risk. N (%) | 143 (18.1) | 101 (16.9) | 42 (21.8) | 0.10 |
Quality of life | ||||
Fair or poor. N (%) | (57.7) | 337 (55.7) | 124 (63.3) | 0.06 |
Mortality | ||||
VACS Index score. Median (p25-p75) | 22 (17–29) | 18 (12–29) | 23 (18–33) | 0.01 |
Estimated risk of all-cause 5-year mortality by VACS Index. Median (p25-p75) | 7.8 (5.8–11.3) | 6.2 (4.2–11.3) | 8.4 (6.2–13.8) | 0.01 |