Table 3 Bivariable and multivariable logistic regression analysis of symptoms according to Clinical Frailty Score (reference value: no frailty)
Symptoms according to frailty | Crude OR (95% CI) | P value | Adjusted OR (95% CI)a | P value |
|---|---|---|---|---|
Duration of symptoms < 5 days prior to admission | ||||
Mild-moderate frailty | 1.57 (1.12–2.21) | 0.008 | 1.11 (0.74–1.64) | 0.59 |
Severe frailty | 3.25 (1.05–5.13) | < 0.001 | 1.99 (1.17–3.28) | 0.010 |
Frailty | 2.00 (1.49–2.69) | < 0.001 | 1.30 (0.90–1.87) | 0.20 |
Fever | ||||
Mild-moderate frailty | 0.52 (0.37–0.73) | < 0.001 | 0.78 (0.53–1.15) | 0.22 |
Severe frailty | 0.3 (0.35–0.81) | 0.003 | 0.84 (0.51–1.38) | 0.56 |
Frailty | 0.52 (0.39–0.70) | < 0.001 | 0.51 (0.80–1.11) | 0.50 |
Dry cough | ||||
Mild-moderate frailty | 0.63 (0.46–0.88) | < 0.001 | 0.66 (0.45–0.97) | 0.037 |
Severe frailty | 0.35 (0.22–0.54) | < 0.001 | 0.40 (0.23–0.67) | 0.001 |
Frailty | 0.52 (0.39–0.70) | < 0.001 | 0.58 (0.40–0.83) | 0.003 |
Wet cough | ||||
Mild-moderate frailty | 0.96 (0.61–1.49) | 0.86 | 0.79 (0.47–1.33) | 0.37 |
Severe frailty | 1.11 (0.65–1.49) | 0.70 | 0.82 (0.43–1.55) | 0.53 |
Frailty | 1.01 (0.70–1.48) | 0.92 | 0.50 (0.81–1.27) | 0.35 |
Dyspnea | ||||
Mild-moderate frailty | 1.10 (0.73–1.67) | 0.63 | 1.39 (0.84–2.28) | 0.19 |
Severe frailty | 1.29 (0.81–2.055) | 0.27 | 1.50 (0.92–2.44) | 0.10 |
Frailty | 0.93 (0.70–1.25) | 0.67 | 1.04 (0.73–1.49) | 0.81 |
Anosmia-dysgeusia | ||||
Mild-moderate frailty | 0.38 (0.20–0.73) | 0.003 | 0.56 (0.27–1.15) | 0.12 |
Severe frailty | 0.11 (0.03–0.47) | 0.003 | 0.21 (0.04–0.95) | 0.044 |
Frailty | 0.29 (0.16–0.52) | < 0.001 | 0.46 (0.23–0.94) | 0.033 |
Myalgia-arthralgia | ||||
Mild-moderate frailty | 0.36 (0.23–0.56) | < 0.001 | 0.53 (0.32–0.88) | 0.014 |
Severe frailty | 0.18 (0.09–0.39) | < 0.001 | 0.30 (0.13–0.70) | 0.005 |
Frailty | 0.29 (0.19–0.44) | < 0.001 | 0.46 (0.29–0.75) | 0.002 |
Asthenia | ||||
Mild-moderate frailty | 0.69 (0.50–0.97) | 0.035 | 0.80 (0.55–1.16) | 0.23 |
Severe frailty | 0.51 (0.33–0.79) | 0.002 | 0.70 (0.42–1.16) | 0.17 |
Frailty | 0.62 (0.47–0.84) | 0.002 | 0.73 (0.54–1.10) | 0.16 |
Diarrhea | ||||
Mild-moderate frailty | 0.82 (0.56–1.21) | 0.33 | 1.25 (0.79–1.97) | 0.34 |
Severe frailty | 0.29 (0.15–0.56) | < 0.001 | 0.52 (0.27–1.18) | 0.13 |
Frailty | 0.61 (0.43–0.87) | 0.007 | 1.05 (0.68–1.62) | 0.83 |
Confusion | ||||
Mild-moderate frailty | 2.21 (1.32–3.69) | 0.002 | 1.59 (0.88–2.85) | 0.16 |
Severe frailty | 4.99 (2.93–8.50) | < 0.001 | 3.14 (1.64–5.97) | < 0.001 |
Frailty | 3.02 (1.99–4.78) | < 0.001 | 2.01 (1.18–3.43) | 0.010 |