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Table 2 FRAX* by quartiles at age 75 and frailty score, fracture and falls

From: Can frailty in conjunction with FRAX identify additional women at risk of fracture - a longitudinal cohort study of community dwelling older women

All variables at 75y

Low FRAX

Q1 (<=19)

FRAX

Q2 (20–26)

FRAX

Q3 (27–33)

High FRAX

Q4 (34+)

No

p-value# Overall

p-value

Q1 vs Q4

 

n = 303

n = 214

n = 279

n = 227

   

Mean

range

Mean

range

Mean

range

Mean

range

   

FRAX MOF no BMD

16.9

(12–19)

22.6

(20 - 26)

30.0

(27–33)

41.8

(34–69)

 

 Frailty index

0.15

(0.00–0.65)

0.16

(0.00–0.70)

0.16

(0.00–0.72)

0.19

(0.00–0.77)

1023

0.015

0.004

Fractures

No

(%)

No

(%)

No

(%)

No

(%)

   

 Prior any fx (20-75y)

30

(6.7)

48

(10.7)

187

(41.7)

183

(40.8)

448

< 0.001

< 0.001

 Prior any fx (50-75y)

21

(5.6)

40

(10.7)

156

(41.7)

157

(42.0)

374

< 0.001

< 0.001

 Prior MOF (50-75y)

19

(8.1)

23

(9.8)

101

(43.0)

92

(39.1)

235

< 0.001

< 0.001

Falls in the last year

No

(%)

No

(%)

No

(%)

No

(%)

   

 1 or more falls reported

66

(26.1)

45

(17.5)

75

(29.6)

67

(26.5)

253

0.118

0.057

 3 or more falls reported

18

(27.7)

10

(15.4)

21

(32.3)

16

(24.6)

65

0.609

0.661

Bone mineral density

Median

IQR

Median

IQR

Median

IQR

Median

IQR

   

 Femoral neck T-score

−1.50

(1.65)

−1.80

(1.60)

−1.98

(1.48)

−2.34

(1.37)

946

< 0.001

< 0.001

 Femoral neck BMD (g/cm2)

0.800

(0.200)

0.764

(0.192)

0.742

(0.178)

0.700

(0.164)

946

< 0.001

< 0.001

  1. *FRAXMOF no BMD. Reported values are means, unless otherwise stated. # p-values calculated by ANOVA, Kruskal Wallace or Chi-square as appropriate