Fig. 1

Selection of the non-treatment group. Data at age 75 was used to calculate FRAX_MOF probabilities. Women in the non-treatment group, i.e. who were ‘low fracture risk’ had no previous MOFs and either a FRAX_MOF < 15% or did not meet requirements for treatment after BMD measurement (i.e. T-score < − 2.5 and FRAX_{MOF BMD} > 20%). Low frailty includes Q1-Q3 and high frailty Q4