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Table 6 Comparison of 1-year functional outcomes among patients with different types of post-stroke cognitive impairment after adjusted for 3 months covariates

From: Persisting cognitive impairment predicts functional dependence at 1 year after stroke and transient ischemic attack: a longitudinal, cohort study

Outcome

Yes (n,%)

Unadjusted analysis

Adjusted analysis

Odds ratio*

(95% CI)

p value

Odds ratio†

(95% CI)

p value

mRS ≥ 2 at 1 year

 A group

38/476(7.98)

 B group

27/210(12.86)

1.70(1.01-2.87)

0.046*

1.63(0.87-3.05)

0.12

 C group

5/50(10.0)

1.28(0.48-3.42)

0.621

1.15(0.37-3.52)

0.81

 D group

61/318(19.18)

2.74(1.77-4.22)

< 0.0001**

1.77(1.03-3.03)

0.039*

SIS-16 < Q1 at 1 year

 A group

88/476(18.49)

  

 B group

54/210(25.71)

1.53(1.03-2.25)

0.03*

1.34(0.86-2.07)

0.19

 C group

10/50(20.00)

1.10(0.53-2.29)

0.79

0.93(0.41-2.09)

0.86

 D group

110/318(34.59)

2.33(1.68-3.23)

< 0.0001**

1.69(1.16-2.47)

0.007**

  1. mRS modified Rankin Scale, SIS-16 Stroke Impact Scale
  2. A group = no PSCI group: with MoCA-2w >22 and MoCA-3 m>22; B group = improved PSCI group: with MoCA-2w 22 and MoCA-3 m>22; C group = delayed PSCI group: MoCA-2w>22 and MoCA-3 m22; D group = persisting PSCI group: with MoCA-2w22 and MoCA-3 m22
  3. Adjusted for gender, age, history of stroke, depression, acute infarction type, mRS score at 3 months, TOAST type, acute stroke type, intracranial atherosclerotic stenosis, dual antiplatelet therapy and lipid-lowering therapy at 3 months
  4. *:<0.05;**:<0.01