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Table 3 Comparison of 3-months functional outcomes among patients with different types of post-stroke cognitive impairment after adjusted for baseline covariates

From: Persisting cognitive impairment predicts functional dependence at 1 year after stroke and transient ischemic attack: a longitudinal, cohort study

Outcome

Yes (n,%)

Unadjusted analysis

Adjusted analysis

Odds ratio*

(95% CI)

p value

Odds ratio†

(95% CI)

p value

mRS ≥ 2 at 3 months (n,%)

 2w3 m A group

40/476(8.40)

 B group

22/210(10.48)

1.01(0.65-1.56)

0.98

0.89(0.56-1.42)

0.64

 C group

6/50(12.00)

1.36(0.67-2.75)

0.396

1.37(0.66-2.87)

0.40

 D group

58/318(18.24)

2.17(1.56-3.02)

< 0.0001**

1.75(1.21-2.51)

0.003**

3 m SIS-16 < Q1 at 3 months

 2w3 m A group

100/476(21.01)

 B group

62/210(29.52)

1.34(0.99-1.81)

0.05

1.18(0.85-1.63)

0.32

 C group

11/50(22.00)

1.54(0.93-2.56)

0.10

1.40(0.81-2.43)

0.23

 D group

111/318(34.91)

1.99(1.55-2.56)

< 0.0001**

1.38(1.04-1.83)

0.025*

  1. mRS modified Rankin Scale, SIS-16 Stroke Impact Scale
  2. A group = no PSCI group: with MoCA-2w>22 and MoCA-3 m>22; B group = improved PSCI group: with MoCA-2w22 and MoCA-3 m>22; C group = delayed PSCI group: with MoCA-2w>22 and MoCA-3 m22; D group = persisting PSCI group: with MoCA-2w22 and MoCA-3 m22
  3. Adjusted for gender, age, history of stroke, sleep disorders, depression, acute infarction type, TOAST type. Infarction type, Intracranial atherosclerotic stenosis, dual antiplatelet therapy at baseline
  4. *:<0.05;**:<0.01