Table 1 Comparison of clinical information between NCI and CIgroups at baseline
Baseline Variables | NCI group (n = 857) | CI group (n = 818) | P value |
|---|---|---|---|
Gender (male, n,%) | 654(76.31) | 583(71.27) | 0.019* |
Average age (years, mean ± SD) | 58.37 ± 10.80 | 62.79 ± 9.59 | < 0.001** |
Body mass index (kg/m2, mean ± SD) | 25.08 ± 3.15 | 25.11 ± 3.24 | 0.88 |
Risk factors | |||
Diabetes (n, %) | 284(33.14) | 257(31.42) | 0.45 |
Hypertension (n, %) | 659(76.90) | 603(73.72) | 0.13 |
Lipid metabolism disorders (n, %) | 385(44.92) | 352(43.03) | 0.44 |
Atrial fibrillation (n, %) | 34(3.97) | 34(4.16) | 0.84 |
Current or previous smoking (n, %) | 324(38.04) | 298(36.43) | 0.50 |
Previous mRS [scores, median (IQR)]) | 0.00(1.00) | 0.00 (1.00) | 0.24 |
Previous stroke (n, %) | 148(17.27) | 215(26.28) | < 0.0001** |
NIHSS at baseline [scores, median (IQR)] | 2.00 (2.00) | 2.00 (2.00) | 0.10 |
Neuropsychiatric symptom at 2 weeks (n, %) | |||
PSQI > 5 | 352(41.07) | 384(46.94) | 0.016* |
ESS > 10 | 100(11.71) | 92(11.27) | 0.78 |
PHQ-9 > 9 | 46(5.40) | 75(9.26) | 0.0025** |
GAD-7 > 9 | 36(4.21) | 48(5.90) | 0.11 |
Stroke subtype for TOAST (n,%) | 0.02* | ||
large artery atherosclerosis | 169(19.72) | 211(25.79) | |
cardiogenic embolism | 40(4.67) | 41(5.01) | |
small artery occlusion | 266(31.04) | 218(26.65) | |
Other/Unknown | 382(44.57) | 348(42.54) | |
Acute infarction type (n,%) | 0.0010* | ||
Single infarction | 401(46.79) | 338(41.32) | |
Multiple infarction | 294(34.31) | 347(42.42) | |
Simple watershed infarction | 10(1.17) | 18(2.20) | |
No infarction | 152(17.74) | 115(14.06) | |
Intracranial atherosclerotic stenosis (ICAS) (n,%) | 154(28.62) | 208(36.30) | 0.006** |
Intravenous thrombolysis (n,%) | 56(6.53) | 42(5.13) | 0.22 |
Dual antiplatelet therapy (n,%) | 368(49.60) | 406(54.79) | 0.045* |
Secondary prevention of stroke at 2 weeks (n,%) | |||
Antiplatelet or anticoagulant therapy | 841(98.13) | 800(97.80) | 0.63 |
Antihypertensive therapy | 467(54.49) | 439(53.67) | 0.73 |
Lipid-lowering therapy | 813(94.87) | 786(96.09) | 0.23 |
Hypoglycemic therapy | 213(24.85) | 205(25.06) | 0.92 |