Table 3 Univariable baseline predictors of falls at follow-up

Covariate

Patients with data on falls in follow-up period available (n = 3681)

Non-fallers (n = 2912)

Fallers (n = 769)

Non- fallers vs. fallers

Age

70–74

815 (22.1)

676 (23.2)

139 (18.1)

0.005

75–79

1007 (27.4)

784 (26.9)

223 (29.0)

80–84

1038 (28.2)

827 (28.4)

211 (24.4)

≥85

821 (22.3)

625 (21.5)

196 (25.5)

Sex

Female

2080 (56.5)

1672 (57,4)

408 (53.1)

0.036

Male

1601 (43.5)

1240 (42, 5)

361 (46.9)

Diagnosis General

Solid tumor

3352 (91.1)

2665 (91.5)

687 (89.3)

0.065

Hematologic malignancy

329 (8.9)

247 (8.5)

82 (10.7)

Diagnosis Specific

New diagnosis

2907 (79.0)

2303 (79.1)

604 (78.5)

0.743

Relapse/Progression

774 (21.0)

609 (20.9)

165 (21.5)

CCI^a

No comorbidities (0)

989 (27.0)

806 (27.8)

183 (23.9)

0.028

Comorbidities (≥1)

2671 (73.0)

2089 (72.2)

582 (76.1)

Polypharmacy^a

No polypharmacy (0–4)

1355 (37.3)

1124 (39.1)

231 (30.3)

< 0.0001

Polypharmacy (≥5)

2279 (62.7)

1748 (60.9)

531 (69.7)

ECOG-PS

Score 0–1

2098 (57.0)

1732 (59.5)

366 (47.6)

< 0.0001

Score 2–4

1583 (43.0)

1180 (40.5)

403 (52.4)

Living situation

Not living alone

2374 (64.5)

1889 (64.9)

485 (63.1)

0.354

Living alone

1307 (35.5)

1023 (35.1)

284 (36.9)

Professional home care^a

No

1696 (46.1)

1382 (47.5)

314 (40.9)

0.001

Yes

1982 (53.9)

1528 (52.5)

454 (59.1)

FS: ADL

Independent (6)

1623 (44.1)

1368 (47.0)

255 (33.2)

< 0.0001

Dependent (> 6)

2058 (55.9)

1544 (53.0)

514 (66.8)

FS: IADL^a

Independent (5(male)/8(female))

1267 (34.5)

1072 (36.9)

195 (25.5)

< 0.0001

Dependent (< 5(male)/8(female)

2401 (65.5)

1831 (63.1)

570 (74.5)

Falls history in the past 12 months

No falls

2400 (65.2)

2039 (70.0)

361 (46.9)

< 0.0001

Falls

1281 (34.8)

873 (30.0)

408 (53.1)

Fear of falling^a

Never

2027 (55.3)

1664 (57.4)

363 (47.3)

< 0.0001

Sometimes / often / always

1637 (44.7)

1233 (42.6)

404 (52.7)

VAS for fatigue^a

No fatigue (0)

937 (26.3)

756 (26.7)

181 (24.4)

0.193

Presence of fatigue (≥1)

2632 (73.7)

2071 (73.3)

561 (75.6)

VAS for pain^a

No pain (0)

1810 (50.1)

1453 (50.8)

357 (47.4)

0.099

Presence of pain (≥1)

1804 (49.9)

1408 (49.2)

396 (52.6)

MMSE^a

Normal cognition (≥24)

2686 (80.2)

2184 (82.1)

502 (72.5)

< 0.0001

Cognitive impairment (< 24)

665 (19.8)

475 (17.9)

190 (27.5)

GDS^a

Not at risk for depression (< 5)

2297 (66.8)

1859 (68.2)

438 (61.4)

0.001

At risk for depression (≥5)

1140 (33.2)

865 (31.8)

275 (38.6)

MNA-SF^a

Normal nutritional status (≥12)

760 (20.7)

624 (21.5)

136 (17.8)

0.023

Risk of malnutrition/ malnourished (< 12)

2913 (79.3)

2284 (78.5)

629 (82.2)