Table 3 Associations between individual symptom, symptoms combination patterns and counts on frailty in the total sample

Individual symptom

Chronic pain

  No

1.00

-

1.00

-

1.00

-

  Yes

1.71(1.16,2.51)

0.007

1.53(0.97,2.42)

0.070

1.89(1.05,3.41)

0.033

Depressive symptoms

  No

1.00

-

1.00

-

1.00

-

  Yes

2.10(1.24,3.55)

0.006

2.29(1.21,4.35)

0.011

3.11(1.24,7.82)

0.016

Poor sleep quality

  No

1.00

-

1.00

-

1.00

-

  Yes

1.79(1.22,2.63)

0.003

1.59(0.99,2.53)

0.053

1.62(0.92,2.84)

0.094

symptom combination patterns

  No symptom

1.00

-

1.00

-

1.00

-

  Chronic pain only

1.82(0.92,3.62)

0.086

1.86(0.83,4.16)

0.133

2.41(0.97,6.04)

0.060

  depressive symptoms only

2.09(0.37,11.91)

0.406

1.69(0.24,12.13)

0.600

1.99(0.13,29.64)

0.618

  Poor sleep quality only

1.70(1.01,2.84)

0.044

1.53(0.83,2.83)

0.177

1.48(0.70,3.13)

0.301

  Chronic pain and depressive symptoms

1.39(0.14,13.83)

0.777

1.00(0.03,31.03)

0.999

1.24(0.03,45.94)

0.906

  Poor sleep quality and depressive symptoms

3.25(1.47,7.20)

0.004

4.02(1.57,10.26)

0.004

6.20(1.42,27.03)

0.015

  Poor sleep quality and chronic pain

2.49(1.41,4.41)

0.002

2.05(1.04,4.05)

0.038

2.22(0.94,5.24)

0.069

  Poor sleep quality and chronic pain and depressive symptoms

4.18(1.73,10.14)

0.002

3.52(1.19,10.44)

0.023

4.79(1.17,19.53)

0.029

Symptom counts

  0

1.00

-

1.00

-

1.00

-

  1

1.74(1.08,2.81)

0.024

1.61(0.92,2.84)

0.097

1.75(0.90,3.41)

0.099

  2

2.63(1.56,4.43)

 < 0.001

2.40(1.28,4.50)

 < 0.001

2.66(1.21,5.86)

0.015

  3

4.18(1.73,10.14)

0.002

3.51(1.19,10.34)

0.023

4.76(1.17,19.35)

0.029