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Table 2 Scores of outcome measures pre/post-intervention and their within-group differences (mean, standard and median) and the results of the comparative analysis of the two groups (p values and effect size)

From: Laser therapy versus pulsed electromagnetic field therapy as treatment modalities for early knee osteoarthritis: a randomized controlled trial

Outcome measure

Measurement time

PEMFT (n = 20)

Mean ± SD, median

Time effect (p value)/effect size

LLLT (n = 20)

Mean ± SD, median

Time effect (p value)/effect size

Group effect (p value)/effect size

Group × Time effect (p value)/effect size

VAS:

 VAS rest (0-10)

Pre

5.2 ± 1.1, 5.0

< 0.0001

0.50

5.1 ± 1.1, 5.0

< 0.0001

0.50

0.85

0.03

 

Post

1.0 ± 0.9, 1.0

3.1 ± 0.8, 3.0

< 0.0001

0.76

 

Delta

−4.2 ± 1.2, − 4.0

 

−2.1 ± 0.8, − 2.0

  

< 0.0001┼

0.72

 VAS walking (0-10)

Pre

6.8 ± 1.0, 7.0

< 0.0001

0.50

6.8 ± 1.1, 7.0

< 0.0001

0.50

0.84

0.03

 

Post

3.6 ± 1.1, 3.5

3.1 ± 0.9, 3.0

0.14

0.2

 

Delta

−3.2 ± 1.0, − 3.0

 

−3.7 ± 1.1, − 4.0

  

0.06

0.30

 VAS rising to standing (0-10)

Pre

8.0 ± 1.0, 8.0

< 0.0001

0.50

8.0 ± 0.8, 8.0

< 0.0001

0.50

0.8291

0.03

 

Post

3.4 ± 1.0, 3.0

4.9 ± 0.8, 5.0

< 0.0001

0.66

 

Delta

−4.7 ± 1.2, − 5.0

 

− 3.2 ± 0.9, − 3.0

  

0.0002┼

0.58

 VAS stairs (0-10)

Pre

8.7 ± 0.6, 9.0

< 0.0001

0.50

8.6 ± 0.5, 9.0

< 0.0001

0.50

0.61/0.10

 

Post

3.9 ± 0.9, 4.0

5.5 ± 1.1, 5.0

< 0.0001

0.63

 

Delta

−3.1 ± 1.0, −5.0

 

−3.2 ± 1.2, − 3.0

  

0.0002┼

0.59

WOMAC:

 Total score (0-96)

Pre

72.2 ± 7.2, 74.5

< 0.0001

0.50

72.5 ± 9.3, 75.5

< 0.0001

0.5

0.63/0.08

 

Post

53.3 ± 9.0, 52.5

62.4 ± 8.7,63.0

0.004

0.45

 

Delta

−19.0 ± 8.0, 19.0

 

−10.0 ± 3.3, 9.5

  

0.0002┼

0.58

 Pain subscale (0-20)

Before

16.1 ± 1.9, 16.0

< 0.0001

0.50

15.1 ± 2.0, 15.5

< 0.0001

0.50

0.1390

0.23

 

After

8.4 ± 1.9, 8.0

10.7 ± 1.8, 11.0

0.0009

0.52

 

Delta

−7.7 ± 2.3, −8.0

 

−4.5 ± 1.3, − 4.0

  

< 0.0001┼

0.66

 Stuffiness subscale (0-8)

Pre

4.5 ± 1.6, 4.0

0.0013

0.26

3.2 ± 1.8, 3.0

0.0002

0.35

0.02/

0.36

 

Post

3.3 ± 1.8, 3.0

2.3 ± 1.3, 2.0

0.11

0.25

 

Delta

−1.2 ± 1.2, − 1.0

 

−0.9 ± 0.8, − 1.0

  

0.51

0.11

 Physical function subscale (0-68)

Pre

51.7 ± 5.5, 51.0

< 0.0001

0.50

54.2 ± 7.2, 56.5

< 0.0001

0.41

0.14

0.23

 

Post

41.6 ± 7.1, 42.0

49.5 ± 7.0, 51.5

0.0015

0.50

 

Delta

−10.1 ± 6.3, − 10.0

 

−4.7 ± 2.9, − 4.0

  

0.001┼

0.52

 TUG (seconds)

Pre

14.9 ± 1.3, 15.0

< 0.0001

0.50

15.0 ± 2.0, 15.0

< 0.0001

0.43

0.8907

0.14

 

Post

11.9 ± 1.4,12.0

13.5 ± 1.9, 13.5

0.0068

0.43

 

Delta

−1.6 ± 1.2, −3.0

 

−1.5 ± 0.9, − 1.5

  

0.0003┼

0.57

 10 MW (seconds)

Pre

12.3 ± 1.0, 12.0

< 0.0001

0.50

12.4 ± 1.3, 13.0

< 0.0001

0.50

0.6128

0.08

 

Post

10.8 ± 1.2, 11.0

10.4 ± 1.2, 10.0

0.0854

0.27

 

Delta

−1.5 ± 0.9, − 1.5

 

−2.1 ± 1.2, − 2.0

  

0.0854

0.27

  1. The level of significance was set at p < 0.05
  2. PEMFT Pulse electromagnetic field therapy, LLLT Low-level laser therapy, SD Standard deviation, Pre Pre-intervention, Post Post-intervention, VAS Visual analog scale, WOMAC Western Ontario and McMaster Universities Osteoarthritis index, TUG Timed up-and-go test, 10 MW 10-m walk test
  3. ┼ - statistically significant