Table 5 Convergent /discriminant validity: Spearman correlations between ADCS-ADL-MCI scores and other ADC-008 trial instruments at baseline/month 36
Instrument | Baseline | Month 36 |
|---|---|---|
r (p-value) | ||
CDR-SB Total Score | -0.33 (< .0001) | -0.77 (< .0001) |
CDR Cognitive Domain Score | -0.27 (< .0001) | -0.74 (< .0001) |
CDR Functional Domain Score | -0.27 (< .0001) | -0.76 (< .0001) |
CDR Home and Hobbies Domain | -0.19 (< .0001) | -0.71 (< .0001) |
CDR Community Affairs Domain | -0.26 (< .0001) | -0.74 (< .0001) |
CDR Personal Care Domain | -0.10 ( 0.0055) | -0.52 (< .0001) |
CDR Memory Domain | -0.17 (< .0001) | -0.72 (< .0001) |
CDR Judgment and Problem Solving Domain | -0.11 ( 0.0015) | -0.65 (< .0001) |
CDR Orientation Domain | -0.26 (< .0001) | -0.69 (< .0001) |
ADAS-Cog Total Score | -0.24 (< .0001) | -0.65 (< .0001) |
MMSE Total Score | 0.2 (< .0001) | 0.64 (< .0001) |
GDS | -0.19 (< .0001) | -0.73 (< .0001) |
BDI | -0.23 (< .0001) | -0.51 (< .0001) |
Qol-AD-Informant Total Score | 0.19 (< .0001) | 0.46 (< .0001) |
NYU Delayed Paragraph Recall Test | 0.25 (< .0001) | 0.56 (< .0001) |
Symbol Digit Modalities Test | 0.24 (< .0001) | 0.52 (< .0001) |