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Table 4 Test–retest reliability: ADCS-ADL-MCI mean change scores and intraclass correlation coefficients between baseline and month 6

From: Psychometric properties of the Alzheimer’s Disease Cooperative Study – Activities of Daily Living for Mild Cognitive Impairment (ADCS-MCI-ADL) scale: a post hoc analysis of the ADCS ADC-008 trial

Definition of Stable Patients a

N (%)

Baseline

Mean (SD) ADCS-ADL-MCI Total Score

Month 6

Mean (SD)

ADCS-ADL-MCI Total Score

Mean Change

(SD) in ADCS-ADL-MCI Total Score

t-test

(p-value)

Intraclass Correlation Coefficient (95% Confidence Interval)

MCI-CGIC, GDS and CDR-SB

108 (16.49)

46.76 (4.35)

46.89 (4.21)

0.13 (3.19)

0.673

0.73 (0.62, 0.80)

MCI-CGIC, GDS and MMSE

69 (10.53)

46.90 (4.15)

46.70 (4.95)

-0.20 (4.02)

0.676

0.62 (0.45, 0.74)

  1. N = 655 patients had an ADCS-ADL-MCI total score measured at both baseline and month 6
  2. a Stable patients defined as those who experienced "no change" on the MCI-CGIC at month 6 and those with a 0-point change between baseline and month 6 on the GDS and CDR-SB or on the GDS and MMSE