Association between cervical artery dissection and spinal manipulative therapy –a medicare claims analysis

Table 3 Ischemic Stroke Controls

Exposure Exposure	n controls	Vertebral Artery Dissection			Carotid Artery Dissection
Exposure Exposure	n controls	n Cases	Odds Ratios (95% Confidence Interval)	P-value	n Cases	Odds Ratios (95% Confidence Interval)	P-value
Exposure Past 7 days
E&M	16,052	94	1.00		88	1.00
CSM	8,223	51	0.84 (0.60, 1.17)	0.31	30	0.68 (0.45, 0.98)	0.047
Neither CSM nor E&M idays	2,945,156	4,411	0.36 (0.30, 0.44)	< 0.0001	5,824	0.52 (0.43, 0.64)	< 0.0001
Exposure Past 14 days
E&M	27,167	150	1.00		150	1.00
CSM	12,691	73	0.90 (0.68, 1.18)	0.46	46	0.70 (0.52, 0.94)	0.02
Neither CSM nor E&M days	2,929,573	4,333	0.39 (0.34, 0.46)	< 0.0001	5,746	0.49 (0.42, 0.56)	< 0.0001
Exposure Past 30 days
E&M	46,416	205	1.00		216	1.00
CSM	19,225	89	0.84 (0.60, 1.17)	0.31	79	0.68 (0.45, 0.98)	0.05
Neither CSM nor E&M days	2,903,790	4,262	0.36 (0.30, 0.44)	< 0.0001	5,647	0.52 (0.43, 0.64)	< 0.0001

E&M: Evaluation and Management for complaint of neck pain; CSM: Cervical Spinal Manipulation