Table 1 Baseline characteristics

Total number of patients

n

1998

537

1461

Age

Median (IQR)

71 (68–75)

70 (67–74)

71 (68–75)

Age groups

 65–69

789 (39.5)

237 (44.1)

552 (37.8)

 70–74

665 (33.3)

179 (33.3)

486 (33.3)

 75–79

432 (21.6)

104 (19.4)

328 (22.5)

 80+

112 (5.6)

17 (3.2)

95 (6.5)

Sex

Female

820 (41.0)

232 (43.2)

588 (40.2)

Male

1178 (59.0)

305 (56.8)

873 (59.8)

Tumour Size

n (% of valid)

n = 1005 ^a

  < 4 cm

N/A

392 (39.0) ^a

 4–6 cm

N/A

452 (45.0) ^a

  > 6 cm

N/A

161 (16.0) ^a

Tumour Site

n (% of valid)

n = 1898

n = 449

n = 1449

 Other

1476 (77.8)

376 (83.7)

1100 (75.9)

 Multifocal

422 (22.2)

73 (16.3)

349 (24.1)

Preoperative symptoms

 Any symptoms present

N/A

1437 (98.4)

 Focal deficit

387 (73.6)

1152 (79.5)

 Seizures

N/A

375 (26.1)

 Symptoms of intracranial pressure

N/A

613 (42.7)

Type of surgical intervention

n (% of valid)

n = 535

n = 1452

 Type of surgery (biopsy only)

119 (22.2)

537 (37.0)

n = 535

n = 1103 ^a

  Biopsy

119 (22.2)

405 (36.7) ^a

  Resection

271 (50.7)

352 (31.9) ^a

  Radical resection

145 (27.1)

346 (31.4) ^a

WHO/ECOG Performance status

n (% of valid)

n = 1959

n = 522

n = 1437

0

462 (23.6)

150 (28.7)

312 (21.7)

1

625 (31.9)

161 (30.8)

464 (32.3)

2

563 (28.7)

140 (26.8)

423 (29.4)

3

243 (12.4)

45 (8.6)

198 (13.8)

4

66 (3.4)

26 (5.0)

40 (2.8)

 By group

0–1

1087 (55.5)

311 (59.6)

776 (54.0)

2

563 (28.7)

140 (26.8)

423 (29.4)

3–4

309 (15.8)

71 (13.6)

238 (16.6)

Postoperative morbidity

 Any complication

62 (11.5)

355 (24.3)

 Local infection

12 (2.2)

64 (4.4)

 Local hematoma

43 (8.0)

118 (8.1)

 Thromboembolism

16 (3.0)

58 (4.0)

 New seizures

N/A

63 (4.3)

 New focal deficit

N/A

179 (12.3)

 Reoperation

N/A

62 (4.3)

  Cause for reoperation

n = 62

  Reoperation and local infection

N/A

15 (24.2)

  Reoperation and local hematoma

N/A

20 (32.3)

N/A

4 (6.5)

Postoperative mortality

120 (6.0)

49 (9.1)

71 (4.9)