Table 2 Protective and risk factors for frailty progression and reversibility
From: Frailty in older people living with HIV: current status and clinical management
| Â | Risk factors associated with frailty progression | Protective factors associated with frailty reversal |
|---|---|---|
Socio-demographic factors | ||
 Older age |  +  |  |
 Younger age |  |  +  |
 Low aging satisfaction |  +  |  |
 Older subjective age |  +  |  |
 Female sex |  +  |  |
 Higher education |  |  +  |
 Employment |  |  +  |
Anthropometric variables and lifestyles | ||
 Smoking pack years |  +  |  |
 Waist to hip ratio |  +  |  |
 Combined exercise-nutrition intervention |  |  +  |
HIV related variables | ||
 Duration of ART exposure |  +  |  |
 HIV virologic suppression |  |  +  |
 CD4 nadir > 500 |  |  +  |
 Absence of AIDS diagnosis |  |  +  |
 Cumulative exposure to zalcitabine (ddC) |  +  |  |
 HIV duration > 20 years |  +  |  |