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Table 3 Results on the association between sarcopenia and the hospitalization-related outcomes, both at the cross-sectional level and at-follow up

From: Healthcare cost expenditures associated to frailty and sarcopenia

 

Cross-sectional analysis

At follow-up

Sarcopenia if frailty is measured via the Frailty Index

Sarcopenia if frailty is measured via the FTS5

Sarcopenia if frailty is measured via the Frailty Index

Sarcopenia if frailty is measured via the FTS5

Model 1

 OR on the probability of being admitted to hospital

1.557** (1.141–2.106)

1.469** (1.133–1.982)

 Coeff on number of hospital admissions

0.221 (− 0.358–0.799)

0.009 (− 0.366–0.384)

 Coeff on length of hospitalization

0.162 (− 0.221–0.545)

− 0.037 (− 0.343–0.269)

 Coeff on hospitalization costs

− 0.032 (− 0.320–0.255)

− 0.063 (− 0.295–0.168)

Model 2

 OR on the probability of being admitted to hospital

1.481* (1.034–2.104)

1.760*** (1.283–2.456)

 Coeff on number of hospital admissions

0.513 (− 0.271–1.298)

−0.011 (− 0.484–0.463)

 Coeff on length of hospitalization

0.159 (− 0.307–0.626)

− 0.140 (− 0.531–0.250)

 Coeff on hospitalization costs

0.055 (− 0.248–0.359)

− 0.051 (− 0.303–0.202)

Model 3

 OR on the probability of being admitted to hospital

1.318 (0.909–1.895)

1.456 (0.991–2.134)

1.629** (1.177–2.301)

1.477* (1.028–2.132)

 Coeff on number of hospital admissions

0.484 (− 0.387–1.355)

0.387 (− 0.507–1.281)

− 0.142 (− 0.669–0.385)

−0.231 (− 0.642–0.180)

 Coeff on length of hospitalization

− 0.033 (− 0.565–0.498)

−0.096 (− 0.599–0.406)

−0.298 (− 0.726–0.129)

−0.244 (− 0.705–0.216)

 Coeff on hospitalization costs

0.025 (− 0.282–0.333)

0.122 (− 0.227–0.471)

−0.093 (− 0.359–0.172)

−0.129 (− 0.374–0.116)

Model 4

 OR on the probability of being admitted to hospital

1.197 (0.824–1.726)

1.318 (0.897–1.934)

1.463* (1.059–2.074)

1.348 (0.941–1.944)

 Coeff on number of hospital admissions

0.357 (− 0.404–1.117)

0.264 (−0.533–1.061)

−0.180 (− 0.654–0.293)

−0.270 (− 0.637–0.097)

 Coeff on length of hospitalization

−0.092 (− 0.558–0.374)

−0.151 (− 0.585–0.283)

−0.035 (− 0.747–0.045)

−0.318 (− 0.735–0.099)

 Coeff on hospitalization costs

0.013 (− 0.283–0.309)

0.091 (− 0.241–0.423)

−0.126 (− 0.373–0.122)

−0.164 (− 0.403–0.075)

  1. 95% confidence intervals in parentheses. *** p < 0.001, ** p < 0.01, * p < 0.05
  2. Model 1 includes sarcopenia as the only independent variable. Model 2 enters sociodemographic characteristics (age and its square and gender) in addition to sarcopenia. Model 3 adds to Model 2 the frailty status, measured by the Frailty Index or the Frailty Trait Score. Models 4 adds the comorbidity severity of individual according to the Charlson Index, which is medium-low if the Charlson Index score is 1 or 2; and high if the Charlson Index score is three or higher. Moreover, polypharmacy is also included if the daily number of drugs the subject is taking is 5 or more