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Table 5 Critical quality appraisal for included cohort studies according to the Critical Appraisal Skills Programme (CASP) [40]

From: Efficacy and safety of adrenergic alpha-1 receptor antagonists in older adults: a systematic review and meta-analysis supporting the development of recommendations to reduce potentially inappropriate prescribing

Authors (Year)

Cohort studies

Focused issue?

Acceptable recruitment of cohorts?

Accurate exposure measurement?

Accurate outcome measurement?

Relevant confounders identified?

Confounders considered in design/analysis?

Follow-ups complete?

Follow-up period long enough?

(Precision of) Results of study? *

Believe in results?

Results applicable?

Results fit evidence?

Chrischilles et al. (2001) [50]

Retrospective cohort study

Y

Y

U

N

N

N

Y

Y

 

N

N

U

Duan et al. (2018) [33]

Retrospective cohort study

Y

Y

Y

Y

Y

Y

Y

U

 

Y

Y

U

Hiremath et al. (2019) [54]

Retrospective cohort study

Y

Y

Y

Y

Y

Y

Y

Y

 

Y

Y

U

Hundemar et al. (2021) [32]

Retrospective cohort study

Y

Y

Y

Y

Y

Y

Y

Y

 

Y

Y

U

Siemens et al. (2021) [55]

Retrospective cohort study

Y

Y

Y

Y

N

N

Y

Y

 

U

U

U

Tae et al. (2019) [56]

Retrospective cohort study

Y

Y

Y

Y

Y

Y

Y

Y

 

Y

Y

U

Welk et al. (2015) [51]

Retrospective cohort study

Y

Y

Y

Y

Y

Y

Y

Y

 

Y

Y

U

  1. Y Yes, N No, U Unclear
  2. * Results are to be found in Table 2
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BMC Geriatrics

ISSN: 1471-2318

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