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Table 2 Univariate and multivariate analyses of factors associated with non-vaccination

From: Factors associated with COVID-19 vaccine uptake among French population aged 65 years and older: results from a national online survey

  Unvaccinated % Crude OR for non-vaccination p Adjusted OR for non-vaccination p
Age category
 65–74 20 1.63 1.22–2.16 <0.001 1.50 1.05–2.14 0.025
 75+ (reference) 13 1    1   
Female (vs male) 20 1.53 1.18–1.98 0.001 0.94 0.67–1.32 0.723
Region
 Auvergne-Rhône-Alpes 12 0.69 0.43–1.13 0.018 0.57 0.31–1.05 0.078
 Bourgogne-Franche-Comté 11 0.58 0.26–1.29   0.61 0.21–1.76  
 Bretagne 21 1.29 0.72–2.34   0.93 0.44–1.95  
 Centre-Val de Loire 22 1.43 0.78–2.62   1.43 0.67–3.03  
 Grand Est 10 0.54 0.28–1.07   0.47 0.22–1.00  
 Hauts-de-France 14 0.81 0.44–1.47   0.69 0.33–1.43  
 Ile-de-France (reference) 17 1    1   
 Normandie 13 0.72 0.31–1.68   0.91 0.37–2.29  
 Nouvelle Aquitaine 19 1.18 0.73–1.89   1.20 0.65–2.20  
 Occitanie 21 1.32 0.83–2.09   1.43 0.80–2.57  
 Pays de la Loire 26 1.70 0.99–2.90   1.32 0.65–2.68  
 Provence-Alpes-Côte d’Azur 21 1.35 0.83–2.18   1.20 0.65–2.22  
Population of residence area
  < 2000 inhabitants 21 1.63 1.17–2.27 0.005 1.78 1.18–2.68 0.053
 2000–20,000 inhabitants (reference) 14 1    1   
 20,000–100,000 inhabitants 15 1.03 0.71–1.48   1.20 0.76–1.88  
  > 100,000 inhabitants 19 1.42 1.01–1.99   1.31 0.85–2.02  
Former occupation
 Farmer, craftman, merchant, company director 24 2.08 1.20–3.59 0.004 1.99 0.99–3.98 0.086
 Executive or higher intellectual profession (reference) 13 1    1 1  
 Intermediate profession 17 1.36 0.98–1.87   1.09 0.73–1.61  
 Employee 21 1.73 1.22–2.46   1.37 0.89–2.11  
 Worker 22 1.84 1.02–3.31   0.93 0.41–2.13  
 Other non-working people 36 3.67 1.07–12.6   8.43 1.27–55.84  
At least one comorbidity associated with risk of severe COVID-19
 Yes 15 0.77 0.59–1.01 0.072 0.83 0.59–1.17 0.343
 No (reference) 18 1    1   
 Unsure 23 1.36 0.71–2.60   0.61 0.25–1.45  
Think previously had COVID-19 (unconfirmed) (yes vs no) 38 3.21 2.05–5.02 <0.0001 4.01 2.17–7.40 <0.001
Concern about catching the COVID-19
 Concerned (reference) 17 1   0.098 1   0.862
 Unconcerned 16 0.96 0.73–1.26   1.10 0.78–1.55  
 Unsure 25 1.65 1.00–2.71   1.04 0.52–2.06  
Suffered economic impact due to the pandemic (yes vs no) 33 2.82 1.99–3.98 <0.0001 2.63 1.71–4.04 <0.001
Following-up news on COVID-19 at least once a week (yes vs no) 16 0.41 0.28–0.59 <0.0001 1.21 0.71–2.08 0.480
General opinion about COVID-19 vaccine safety
 Safe (reference) 9 1   <0.0001 1   <0.001
 Unsafe 38 6.54 4.80–8.91   6.79 4.50–10.26  
 Unsure 23 3.25 2.26–4.66   2.78 1.88–4.09  
Attitude towards vaccination in general
 Supportive (reference) 12 1   <0.0001 1   <0.001
 Unsupportive 48 6.94 5.00–9.64   4.24 2.77–6.49  
 Unsure 46 6.23 3.22–12.07   5.12 1.98–13.23  
Trust in information on vaccines delivered by doctor (yes vs no) 15 0.14 0.09–0.21 <0.0001 0.28 0.16–0.48 <0.001
Trust in government’s actions to control the epidemic (yes vs no) 9 0.27 0.20–0.36 <0.0001 0.50 0.34–0.74 0.001
Political party affiliation
 Far-Left 22 2.21 1.22–4.03 <0.0001 1.12 0.52–2.38 0.043
 Left 13 1.15 0.68–1.95   0.70 0.37–1.32  
 Green 23 2.34 1.25–4.39   0.89 0.41–1.93  
 Center (reference) 11 1    1   
 Right 11 0.96 0.58–1.60   0.40 0.21–0.76  
 Far-Right 32 3.75 2.37–5.94   1.02 0.55–1.88  
 Other 25 2.72 0.92–8.03   0.79 0.16–3.81  
 Neither 20 2.06 1.35–3.14   0.66 0.38–1.14