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Table 1 Baseline characteristics of participants according to depressive symptoms status

From: Associations of multiple chronic disease and depressive symptoms with incident stroke among Chinese middle-aged and elderly adults: a nationwide population-based cohort study

Variables

Baseline survey (n = 8,389)

Depressive symptoms, n (%)

P-value#

Yes (n = 1659)

No (n = 6730)

Gender

  Male

3905 (46.5)

575 (34.7)

3330 (49.5)

 < 0.001

  Female

4478 (53.4)

1083 (65.3)

3395 (50.5)

 

  Missing data

6 (0.1)

   

Age, mean (SD), year

58.5 (9.1)

59.9 (9.0)

58.1 (9.0)

 < 0.001

Marital status

  Married

7521 (89.7)

1372 (82.7)

6149 (91.4)

 < 0.001

  Separated or divorced

81 (1.0)

35 (2.1)

46 (0.7)

 

  Widowed

745 (8.9)

239 (14.4)

506 (7.5)

 

  Never married

42 (0.5)

13 (0.8)

29 (0.4)

 

Education level

  Primary school or below

5554 (66.2)

1322 (79.7)

4232 (62.9)

 < 0.001

  Middle school

1814 (21.6)

246 (14.8)

1568 (23.3)

 

  High school or above

1015 (12.1)

91 (5.5)

924 (13.7)

 

  Missing data

6 (0.1)

   

Ever smoking

  No

5169 (61.6)

1120 (67.5)

4049 (60.2)

 < 0.001

  Yes

3220 (38.4)

539 (32.5)

2681 (39.8)

 

Last year drinking

  No

6223 (74.2)

1332 (80.3)

4891 (72.7)

 < 0.001

  Yes

2166 (25.8)

327 (19.7)

1839 (27.3)

 

Residence

  Rural

7601 (90.6)

1563 (94.2)

6038 (89.7)

 < 0.001

  Urban

787 (9.4)

96 (5.8)

691 (10.3)

 

  Missing data

1 (0)

   

BMI, mean (SD), kg/m2

23.73 (4.45)

23.25 (4.16)

23.85 (4.51)

 < 0.001

Systolic pressure, median (IQR), mmHg

126.67 (114.76, 141.33)

125.67 (113.67, 141.67)

127.00 (115.00, 141.33)

0.115

Diastolic pressure, median (IQR), mmHg

75.00 (67.33, 83.33)

74.33 (66.67, 82.67)

75.00 (67.67, 83.33)

0.040

hs-CRP, median (IQR), mg/dL

1.04 (0.54, 2.17)

1.02 (0.54, 2.31)

1.04 (0.55, 2.14)

0.874

FBG, mean (SD), mmol/L

6.11 (1.94)

6.05 (1.88)

6.13 (1.96)

0.144

HbA1c, mean (SD) (%)

5.28 (0.82)

5.31 (0.87)

5.27 (0.81)

0.078

Serum creatinine, mean (SD), μmol/L

69.05 (21.33)

65.91 (15.81)

69.83 (22.42)

 < 0.001

Total Cholesterol, mean (SD), mmol/L

5.02 (1.01)

5.07 (1.00)

5.01 (1.01)

0.035

Triglyceride, mean (SD), mmol/L

1.50 (1.21)

1.42 (1.03)

1.52 (1.25)

0.005

HDL-c, mean (SD), mmol/L

1.32 (0.40)

1.36 (0.41)

1.31 (0.39)

 < 0.001

LDL-c, mean (SD), mmol/L

3.04 (0.90)

3.10 (0.90)

3.03 (0.90)

0.005

Hemoglobin, mean (SD), g/dL

14.43 (2.18)

14.20 (2.17)

14.48 (2.18)

 < 0.001

Uric Acid, mean (SD), μmol/L

265.46 (75.17)

252.62 (72.76)

268.63 (75.42)

 < 0.001

Cystatin C, mean (SD), mg/L

1.01 (0.28)

1.02 (0.26)

1.01 (0.29)

0.119

Hypertension

  No

5249 (62.6)

1002 (60.4)

4247 (63.1)

0.041

  Yes

3140 (37.4)

657 (39.6)

2483 (36.9)

 

Dyslipidemia

  No

5885 (70.2)

1176 (70.9)

4709 (70.0)

0.465

  Yes

2504 (29.8)

483 (29.1)

2021 (30.0)

 

Heart problems

  No

7451 (88.8)

1369 (82.5)

6082 (90.4)

 < 0.001

  Yes

938 (11.2)

290 (17.5)

648 (9.6)

 

Diabetic Status

  Others

3494 (41.6)

722 (43.5)

2772 (41.2)

0.225

  Prediabetes

3783 (45.1)

725 (43.7)

3058 (45.4)

 

  Diabetes

1112 (13.3)

212 (12.8)

900 (13.4)

 

Chronic kidney disease

  No

7880 (93.9)

1495 (90.1)

6385 (94.9)

 < 0.001

  Yes

509 (6.1)

164 (9.9)

345 (5.1)

 

CESD-10 scores, median (IQR)

7.00 (3.00, 11.00)

16.00 (14.00, 20.00)

6.00 (3.00, 8.00)

 < 0.001

  1. Abbreviation: SD Standard deviation, IQR Interquartile range, hs-CRP High sensitivity C-reactive protein, FBG Fasting blood glucose, HDL-c HDL cholesterol, LDL-c LDL cholesterol, BMI Body mass index, CESD-10 The 10-item Center for Epidemiology Scale for Depression (CESD-10)
  2. # The Chi-square test for categorical variables and the t-test or Wilcoxon test for continuous variables were used to assess the differences between the groups