Fig. 4

Biological pathways exclusive to FRAF vs NORF. A. Significant IPA canonical pathways (y-axis) uniquely identified in the FRAF vs NORF comparison group are plotted by –Log₁₀ transformed p-values (x-axis). B. Significant GO biological processes (y-axis) exclusively identified in the FRAF vs NORF comparison group, plotted by Z-score (x-axis). C. All significant GO molecular functions (y-axis) identified in the FRAF vs NORF group, plotted by Z-score (x-axis). Refer to Additional files 7 and 13, 14, 15 for complete lists of IPA canonical pathways and GO terms. Abbreviations: “Reg. of the EMT by GFs Pathway” = Regulation of the Epithelial Mesenchymal Transition by Growth Factors Pathway; “DM” = Diabetes Mellitus; “ALS” = Amyotrophic lateral sclerosis; “(-)” = negative; “( +)” = positive; “REG.” = regulation; “FGFR” = fibroblast growth factor receptor; “GPCR” = G-protein coupled receptor