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Table 2 The association between hormones and S-Klotho concentration among the U.S. males in NHANES 2011–2016

From: Association between testosterone and serum soluble α-klotho in U.S. males: a cross-sectional study

 

Number of Subjects

Unadjusted model

Adjusted modela

β, (95% CI)

p values

β, (95% CI)

p values

TT

3749

0.133 (0.056, 0.210)

0.001

0.165 (0.065,0.266)

0.004

E2

2526

1.963 (0.388, 3.538)

0.021

2.232 (0.588, 3.876)

0.032

SHBG

2356

1.235 (0.627, 1.843)

 < 0.001

2.013 (1.173, 2.583)

0.002

T/E2 ratio

2525

220.419 (-443.164, 884.002)

0.520

455.345 (-398.496, 1309.186)

0.331

TD

3749

-13.794 (-34.003, 6.416)

0.188

-18.062 (-40.968, 4.843)

0.135

  1. Abbreviation: NHANES The National Health and Nutrition Examination Survey, CI Confidence interval, TT Total testosterone, E2 Estradiol, SHBG The sex hormone-binding globulin, T/E2 ratio The ratio of testosterone to estradiol, TD Testosterone deficiency
  2. a The model was fully adjusted by age, race, education level, marital status, family income-poverty ratio, BMI, time of venipuncture, CAD score, smoking status, alcohol consumption, and physical activity