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Table 2 Neuroimaging findings of CSVD patients

From: Structural brain network measures in elderly patients with cerebral small vessel disease and depressive symptoms

  CSVD−D
n = 34
CSVD+D
n = 36
p-value
Total CSVD Burden
 CSVD score, median (IQR) 1 (1) 1.5 (1) 0.415
 Grade 1, n (%) 23 (67.6) 18 (50.0)  
 Grade 2, n (%) 8 (23.5) 12 (33.3)  
 Grade 3, n (%) 3 (8.8) 5 (13.9)  
 Grade 4, n (%) 0 (0) 1 (2.8)  
Cerebrovascular lesions
 WMH Fazekas 0–1, n (%) 9 (26.5) 4 (11.1) 0.099
 WMH Fazekas 2–3, n (%) 25 (73.5) 32 (88.9)
 Lacunes occurrence, n (%) 12 (35.3) 18 (50.0) 0.214
 CMBs occurrence, n (%) 8 (23.5) 9 (25.0) 0.886
 EPVS occurrence, n (%) 3 (8.8) 2 (5.6) 0.596
Neuroimaging measures
 Total GMV, mean (SD) 32.81 (2.33) 32.74 (2.11) 0.896
 Total WMV, mean (SD) 26.94 (3.21) 27.39 (2.56) 0.435
 Total WMHV, mean (SD) 3.14 (1.95) 4.01 (2.27) 0.091
  1. Data represent mean ± standard deviation or median (interquartile range). * means p-value < 0.05 was considered to be statistically significant
  2. Abbreviations: CSVD Cerebral small vessel disease; CSVD-D CSVD without depression symptoms, CSVD+D CSVD with depression symptoms, Con Control group, CMBs Cerebral microbleeds, WMH score White matter hyperintensity score; EPVS Enlarged perivascular spaces, TIV Total intracranial volume, Total GMV gray matter volume as % of TIV, Total WMV White matter hyperintensity as % of TIV, Total WMHV White matter hyperintensity volume as % of TIV, SD Standard deviation, IQR Interquartile range