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Table 2 Neuroimaging findings of CSVD patients

From: Structural brain network measures in elderly patients with cerebral small vessel disease and depressive symptoms

 

CSVD−D

n = 34

CSVD+D

n = 36

p-value

Total CSVD Burden

 CSVD score, median (IQR)

1 (1)

1.5 (1)

0.415

 Grade 1, n (%)

23 (67.6)

18 (50.0)

 

 Grade 2, n (%)

8 (23.5)

12 (33.3)

 

 Grade 3, n (%)

3 (8.8)

5 (13.9)

 

 Grade 4, n (%)

0 (0)

1 (2.8)

 

Cerebrovascular lesions

 WMH Fazekas 0–1, n (%)

9 (26.5)

4 (11.1)

0.099

 WMH Fazekas 2–3, n (%)

25 (73.5)

32 (88.9)

 Lacunes occurrence, n (%)

12 (35.3)

18 (50.0)

0.214

 CMBs occurrence, n (%)

8 (23.5)

9 (25.0)

0.886

 EPVS occurrence, n (%)

3 (8.8)

2 (5.6)

0.596

Neuroimaging measures

 Total GMV, mean (SD)

32.81 (2.33)

32.74 (2.11)

0.896

 Total WMV, mean (SD)

26.94 (3.21)

27.39 (2.56)

0.435

 Total WMHV, mean (SD)

3.14 (1.95)

4.01 (2.27)

0.091

  1. Data represent mean ± standard deviation or median (interquartile range). * means p-value < 0.05 was considered to be statistically significant
  2. Abbreviations: CSVD Cerebral small vessel disease; CSVD-D CSVD without depression symptoms, CSVD+D CSVD with depression symptoms, Con Control group, CMBs Cerebral microbleeds, WMH score White matter hyperintensity score; EPVS Enlarged perivascular spaces, TIV Total intracranial volume, Total GMV gray matter volume as % of TIV, Total WMV White matter hyperintensity as % of TIV, Total WMHV White matter hyperintensity volume as % of TIV, SD Standard deviation, IQR Interquartile range