Structural brain network measures in elderly patients with cerebral small vessel disease and depressive symptoms

BMC Geriatrics

Table 1 Demographic and clinical characteristics

	Con n = 45	CSVD−D n = 34	CSVD+D n = 36	p-value
Demographic factors
Male (%)	20 (44.4)	19 (55.9)	19 (52.8)	0.569
Age, mean (SD)	63.33 (6.03)	63.06 (5.22)	63.42 (6.53)	0.966
Education, mean (SD)	10.60 (2.42)	10.56 (2.14)	10.25 (2.64)	0.788
Vascular risk factors
Hypercholesterolemia (%)	–	8 (23.5)	9 (25.0)	0.886
Diabetes Mellitus (%)	–	7 (20.6)	12 (33.3)	0.231
Hypertension (%)	–	17 (50.0)	20 (55.6)	0.642
Smoking (%)	–	17 (50.0)	17 (47.2)	0.816
Drinking (%)	–	15 (44.1)	16 (44.4)	0.978
Neuropsychological tests
MoCA, mean (SD)	27.80 (1.47)	27.59 (1.58)	27.42 (1.38)	0.513
HAMD, mean (SD)	1.91 (0.99)	2.29 (1.61)	11.53 (2.66)	< 0.001^a,b,c

Data represent number (percentage) and mean (standard deviation) for normally distributed data; SD, standard deviation; p-value < 0.05 was considered to be statistically significant
Abbreviations: CSVD Cerebral small vessel disease, CSVD−D CSVD without depression symptoms; CSVD+D CSVD with depression symptoms, Con Control group, MOCA Montreal Cognitive Assessment, HAMD Hamilton Depression Rating Scale; a–c: post hoc analysis revealed the source of ANOVA (a: Con vs. CSVD−D, b: Con vs. CSVD+D, and c: CSVD−D vs. CSVD+D)

ISSN: 1471-2318