Osteosarcopenic obesity and its components—osteoporosis, sarcopenia, and obesity—are associated with blood cell count-derived inflammation indices in older Chinese people

Nie, Yi-zhen; Yan, Zhao-qi; Yin, Hui; Shan, Ling-han; Wang, Jia-hui; Wu, Qun-hong

doi:10.1186/s12877-022-03225-x

Table 3 Correlations of inflammation indices with common parameters for osteoporosis, obesity, and sarcopenia assessment

From: Osteosarcopenic obesity and its components—osteoporosis, sarcopenia, and obesity—are associated with blood cell count-derived inflammation indices in older Chinese people

		ASMI r P	HGS r P	GS r P	PBF r P	aBMD_L1-L4, r P	aBMD_{total hip} r P	aBMD_{femoral neck} r P
0	WBC	0.373	0.191	0.209	− 0.158	0.027	− 0.055	0.034
0		0.006	0.172	0.132	0.259	0.851	0.697	0.809
1		0.130	0.060	−0.068	− 0.080	0.030	− 0.037	0.014
1		0.068	0.400	0.341	0.265	0.678	0.604	0.840
2		0.097	0.029	−0.062	−0.065	− 0.001	− 0.048	− 0.066
2		0.097	0.626	0.295	0.270	0.983	0.414	0.262
3		−0.057	−0.059	0.104	0.095	−0.039	0.021	0.014
3		0.562	0.545	0.287	0.333	0.691	0.833	0.882
0	SIRI	0.142	0.076	0.196	0.080	0.090	−0.080	0.089
0		0.309	0.588	0.160	0.567	0.522	0.568	0.528
1		0.238	0.163	−0.112	−0.225	0.060	0.020	0.094
1		0.001	0.022	0.117	0.002	0.407	0.778	0.188
2		0.155	0.078	−0.153	−0.200	0.047	0.100	0.079
2		0.008	0.186	0.009	0.001	0.423	0.088	0.177
3		0.158	0.199	0.040	−0.013	0.015	0.083	0.069
3		0.105	0.040	0.683	0.893	0.882	0.395	0.482
0	AISI	0.173	−0.017	0.150	0.192	0.044	−0.136	0.058
0		0.216	0.905	0.285	0.169	0.753	0.333	0.679
1		0.163	0.082	−0.131	−0.133	0.003	0.004	0.083
1		0.022	0.251	0.066	0.063	0.965	0.960	0.250
2		0.084	0.029	−0.131	−0.135	−0.035	0.060	0.062
2		0.153	0.617	0.025	0.021	0.552	0.309	0.294
3		0.042	0.081	0.014	0.121	−0.052	0.075	0.027
3		0.668	0.408	0.889	0.214	0.595	0.440	0.785
0	NLR	−0.118	−0.035	0.130	0.160	−0.025	0.050	0.150
0		0.399	0.802	0.353	0.251	0.862	0.724	0.454
1		0.085	−0.002	−0.095	−0.103	0.110	0.153	0.167
1		0.238	0.972	0.185	0.152	0.125	0.032	0.019
2		−0.007	−0.043	− 0.219	−0.106	− 0.039	−0.033	− 0.099
2		0.905	0.464	<0.001	0.071	0.505	0.569	0.092
3		0.032	0.217	0.050	−0.023	0.028	0.144	0.142
3		0.745	0.025	0.607	0.812	0.777	0.139	0.144
0	PLR	−0.181	−0.173	−0.069	0.227	0.042	−0.044	0.031
0		0.195	0.216	0.623	0.101	0.768	0.754	0.827
1		−0.136	−0.175	−0.097	0.106	−0.067	0.038	0.062
1		0.057	0.014	0.175	0.139	0.353	0.599	0.392
2		−0.193	−0.125	−0.014	0.078	−0.097	− 0.0297	−0.010
2		0.001	0.033	0.807	0.184	0.099	0.614	0.860
3		−0.027	0.049	−0.019	0.097	−0.047	0.049	0.001
3		0.786	0.618	0.848	0.319	0.633	0.616	0.990
0	LMR	−0.088	−0.054	−0.093	− 0.150	−0.122	0.098	−0.104
0		0.532	0.701	0.508	0.284	0.384	0.485	0.459
1		−0.149	−0.132	0.111	0.126	−0.059	−0.022	− 0.099
1		0.038	0.066	0.120	0.078	0.411	0.76	0.169
2		−0.114	−0.049	0.094	0.164	−0.055	−0.105	− 0.114
2		0.052	0.401	0.110	0.005	0.347	0.074	0.051
3		−0.250	−0.202	0.135	0.035	−0.042	−0.133	− 0.105
3		0.009	0.037	0.165	0.723	0.667	0.172	0.281

Abbreviations: ASMI Appendicular skeletal muscle mass index, WBC White blood cells, SIRI Systemic inflammation response index, AISI Aggregate index of systemic inflammation, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, and LMR Lymphocyte-to-monocyte ratio, ASMI Appendicular lean mass index, HGS Handgrip strength, GS Gait speed, aBMD_L1–4, Bone mineral density at the lumbar spine1 to 4, aBMD_{total hip}, Bone mineral density at the total hip, aBMD_{femoral neck} Bone mineral density at femoral neck
Spearman’s r was used for correlations between non-normal distribution variables and Pearson’s r for correlations between normal distribution variables, and P < 0.05 was considered statistically significant

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