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Table 3 Factors to consider for transplant evaluation of a patient who is unlikely to outlive the graft, 65 years or older, frail, or cognitively impaired

From: Defining the ethical considerations surrounding kidney transplantation for frail and cognitively impaired patients: a Delphi study of geriatric transplant experts

 

% of experts who rated the factor after two rounds as very important or important to consider when listing a KT candidate for transplantation who is:

Factor

Unlikely to outlive the graft

Aged ≥65 years

Frail

Cognitively impaired

Health Related Quality of Life (HRQOL)

95%

95%

85%

95%

Social Support

50%

100%

95%

100%

Medication adherence

***

100%

***

95%

Low or no frailty*

***

95%

***

***

Younger Age

85%

*

90%

70%

Good functional status*

***

100%

***

***

Benefit over dialysis to patient*

75%

***

***

***

Low comorbidity burden*

***

80%

***

***

No medical contraindications*

***

95%

90%

***

Symptoms on dialysis

60%

***

35%

***

Dependence in activities of daily living

40%

35%

**

**

Race/Ethnicity

**

**

**

**

Sex

**

**

**

**

Frailty could be reversible or improved (from transplant or prehab)

***

***

95%

***

Likelihood for success or benefit from surgery

***

***

95%

***

Degree of cognitive impairment (e.g., mild vs. dementia)

***

***

***

95%

Cognitive impairment related to ESRD/HD symptoms and not a primary neurocognitive disorder

***

***

***

75%

  1. *New factor that was suggested by ≥2 experts in round 1, then subsequently included in round 2
  2. ** Experts were not asked to rate factors in round 2 that were rated very important/important by < 25% in round 1
  3. *** Factor not relevant to this patient